2024-03-29T10:37:49Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/1281962016-10-20T06:36:49Zcom_10261_135com_10261_4com_10261_54com_10261_1col_10261_388col_10261_307
About the vibrational spectroscopy in the diagnosis of Alzheimer's disease | Sobre la espectroscopía vibracional en el diagnóstico de la enfermedad de Alzheimer
Carmona, Pedro
López-Tobar, Eduardo
Molina, Marina
Toledano Gasca, Adolfo
Consejo Superior de Investigaciones Científicas (España)
6 pags.; 6 figs.
Two-dimensional correlation vibrational spectroscopy is emerging as an alternative technique to detect relatively small alterations in composition and molecular structure of complex biological systems such as blood plasma resulting from pathological, physical and chemical processes occuring in body. In this paper the main concepts considered in the use of infrared and Raman spectroscopies in their two-dimensional form and their application in the search for markers for the diagnosis of Alzheimer's disease are described. Some examples of representation of spectral markers in ROC curves showing accuracies in classifications of samples greater than 80% are also discussed.
Gran parte de los trabajos aquí mencionados han sido
subvencionados con un proyecto del Plan Nacional 2009 y
un proyecto INNPACTO 2012, así como con un
Convenio/Contrato CSIC-Lab. Raman-Health.
Peer Reviewed
2015
2016-01-27T11:13:28Z
artículo
http://purl.org/coar/resource_type/c_6501
issn: 1697-428X
Anales de la Real Academia Nacional de Farmacia 81: 19- 24 (2015)
http://hdl.handle.net/10261/128196
http://dx.doi.org/10.13039/501100003339
Publisher's version
Sí
none
Real Academia Nacional de Farmacia (España)