2024-03-28T09:23:52Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/2009422021-12-28T16:52:40Zcom_10261_54com_10261_1col_10261_307
Romero-Ramírez, Lorenzo
Nieto-Sampedro, Manuel
Barreda-Manso, M. Asunción
2020-02-17T13:16:18Z
2020-02-17T13:16:18Z
2017
BioMed Research International 2017: 6953156 (2017)
2314-6133
http://hdl.handle.net/10261/200942
10.1155/2017/6953156
2314-6141
28536699
Central nervous system (CNS) injuries, caused by cerebrovascular pathologies or mechanical contusions (e.g., traumatic brain injury, TBI) comprise a diverse group of disorders that share the activation of the integrated stress response (ISR). This pathway is an innate protective mechanism, with encouraging potential as therapeutic target for CNS injury repair. In this review, we will focus on the progress in understanding the role of the ISR and we will discuss the effects of various small molecules that target the ISR on different animal models of CNS injury.
http://creativecommons.org/licenses/by/4.0/
openAccess
Integrated Stress Response as a Therapeutic Target for CNS Injuries
artículo de revisión