2024-03-29T04:54:41Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/1661762018-06-13T00:56:22Zcom_10261_74com_10261_6col_10261_453
Cala, Antonio
Rial, Carlos
Fernández-Aparicio, Mónica
Molinillo, José M. G.
Valera, R. M.
Rubiales, Diego
Macías, Francisco A.
2018-06-12T12:01:56Z
2018-06-12T12:01:56Z
2015-07
XXXV Reunión Bienal de la Real Sociedad Española de Química (2015)
http://hdl.handle.net/10261/166176
http://dx.doi.org/10.13039/501100000780
http://dx.doi.org/10.13039/501100003329
Parasitic weeds cause high damage on crops production each year and their seed bank
is almost indestructible. The strategy of suicidal germination is based on the principle
of applying germination stimulants in the soil to make the parasites germinate before
sowing a crop to which they can attach. This process leads the parasitic seedlings to an
inevitable death due to nutrient starvation.
[1]
Synthetic analogues of germination-
inducing factors constitute a cheap and feasible strategy to control seed bank of
weeds, although, the stimulant should be easily synthesized and economical to afford
mass production.
We synthesized a family of N-substituted phthalimides with a lactone ring and
containing different substituents in the aromatic ring. The synthetic procedure is
simple and starts with commercially available phthalimides. We called this compounds
phthalimide-lactones. Recently, we have also synthetized new amide derivatives with
different chain sizes in positions 3 and 4. The complete collection (PL00-18) was
purified and assayed against parasitic weeds
O. minor, O. cumana
and
P. ramosa.
In summary, our structure-activity relationship analysis demonstrated high selectivity
according with the structural modification and parasitic species tested. Some of our
structural modifications induced levels of germination comparable with the positive
control GR-
24, a synthetic analogue of strigolactones, natural and most active host-
derived germination-inducing factors. The use of these compounds as new leads for
weed control is discussed.
eng
closedAccess
Parasitic weeds
Broomrape
Phthalimide
Strigolactone
Seed germination
Phthalimide-lactones stimulate germination of parasitic weeds
póster de congreso