2024-03-29T12:01:47Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/1327592022-07-01T09:35:57Zcom_10261_7102com_10261_1col_10261_7103
Martín, Guiomar
Leivar, Pablo
Ludevid, M. Dolors
Tepperman, James
Quail, Peter H.
Monte, Elena
2016-05-30T11:18:49Z
2016-05-30T11:18:49Z
2016-05-06
Nature Communications 7: 11431 (2016)
2041-1723
http://hdl.handle.net/10261/132759
10.1038/ncomms11431
http://dx.doi.org/10.13039/501100004837
http://dx.doi.org/10.13039/501100003329
http://dx.doi.org/10.13039/501100003176
http://dx.doi.org/10.13039/501100002809
http://dx.doi.org/10.13039/501100000780
http://dx.doi.org/10.13039/100000002
http://dx.doi.org/10.13039/100007917
http://dx.doi.org/10.13039/100000199
27150909
Plastid-to-nucleus retrograde signals emitted by dysfunctional chloroplasts impact photomorphogenic development, but the molecular link between retrograde- and photosensory-receptor signalling has remained unclear. Here, we show that the phytochrome and retrograde signalling (RS) pathways converge antagonistically to regulate the expression of the nuclear-encoded transcription factor GLK1, a key regulator of a light-induced transcriptional network central to photomorphogenesis. GLK1 gene transcription is directly repressed by PHYTOCHROME-INTERACTING FACTOR (PIF)-class bHLH transcription factors in darkness, but light-activated phytochrome reverses this activity, thereby inducing expression. Conversely, we show that retrograde signals repress this induction by a mechanism independent of PIF mediation. Collectively, our data indicate that light at moderate levels acts through the plant’s nuclear-localized sensory-photoreceptor system to induce appropriate photomorphogenic development, but at excessive levels, sensed through the separate plastid-localized RS system, acts to suppress such development, thus providing a mechanism for protection against photo-oxidative damage by minimizing the tissue exposure to deleterious radiation.
eng
http://creativecommons.org/licenses/by/4.0/
openAccess
Phytochrome and retrograde signalling pathways converge to antagonistically regulate a light-induced transcriptional network
artículo