2024-03-28T09:29:20Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/1354642020-05-25T16:52:37Zcom_10261_125com_10261_2col_10261_1386
DIGITAL.CSIC
author
Álvarez Sieiro, Patricia
author
Álvarez Sieiro, María Cruz
author
Redruello, Begoña
author
Ladero Losada, Víctor Manuel
author
Fernández García, María
author
Álvarez González, Miguel Ángel
2016-08-10T11:18:09Z
2016-08-10T11:18:09Z
2015-11-26
WO2015177366 A1
http://hdl.handle.net/10261/135464
PCT/EP15/061467
The invention relates to a bacterial strain, Lactobacillus casei IPLA12038 with deposit number CECT 8590, and its use for the degradation of gluten, gliadin or derivative peptides. The strain has been isolated from an acidic dough used to make bread. Its advantages include the ability to use gliadin as nitrogen source, possess peptidase activities involved in the degradation of it and be able to completely degrade the immunotoxic (33) amino acid peptide involved in triggering of celiac disease in a short period of time. The fact of considering it a GRAS and QPS microorganism, isolated from a fermented food, sensitive to antimicrobial gastrointestinal agents and resistant to gastrointestinal conditions tested in vitro, guarantees its use as a probiotic or nutraceutical supplement.
eng
openAccess
New strain of lactobacillus casei with ability to degrade the immunotoxic peptide from gluten
solicitud de patente
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URL
https://digital.csic.es/bitstream/10261/135464/1/WO2015177366A1.pdf
File
MD5
5854eb5a68e5ee8165f40cc0236953e1
2057616
application/pdf
WO2015177366A1.pdf