2024-03-29T00:50:15Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/549682018-08-16T11:45:12Zcom_10261_47com_10261_8col_10261_300
00925njm 22002777a 4500
dc
Prado-Álvarez, María
author
Rotllant, Josep
author
Gestal, C.
author
Novoa, Beatriz
author
Figueras Huerta, Antonio
author
2009
The alternative pathway is considered to be the most ancient route for activation of the complement
system. Herein, we report the characterization of C3 and factor B-like proteins in the clam Ruditapes
decussatus, termed Rd-C3 and Rd-Bf-like. The Rd-C3 is a three-chain protein, similar to other protoC3
proteins, and the Rd-Bf-like is composed of two complement control protein modules (CCP domains)
that differ from other described Bf proteins. The inoculation of clams with live bacteria did not result in
induction of these functions, but inhibited the expression of Rd-C3 and Rd-Bf-like.
Fish and Shellfish Immunology 26(2): 305-315 (2009)
1050-4648
http://hdl.handle.net/10261/54968
10.1016/j.fsi.2008.11.015
Clam
Ruditapes decussatus
Complement
C3
Factor B
Gene expression
Characterization of a C3 and a factor B-like in the carpet-shell clam, Ruditapes decussatus