2024-03-28T21:19:29Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/378912014-03-21T10:37:59Zcom_10261_38com_10261_5col_10261_291
00925njm 22002777a 4500
dc
Bellomo, Ana
author
Bonilla, Julia B.
author
López-Prados, Javier
author
Martín-Lomas, Manuel
author
González, David
author
2009-09-14
The first synthesis of two fagopyritol β-analogues (β-d-galactopyranosyl-(1′→1)-conduramine F-4 and β-d-galactopyranosyl-(1′→3)-4-aminodeoxy-l-chiro-inositol) has been accomplished by a chemoenzymatic route in satisfactory yields. The key step of the synthesis is the TMSOTf-promoted glycosylation reaction of a deoxyconduritol derivative. The methodology is amenable to scale-up and expandable to the preparation of other pseudofagopyritols.
Tetrahedron Asymmetry 17(8): 2061-2064 (2009)
0957-4166
http://hdl.handle.net/10261/37891
10.1016/j.tetasy.2009.08.011
Synthesis
fagopyritol β-analogues
Aminoinositol
Chemoenzymatic
Glycoside
Chemoenzymatic synthesis of glycosyl-deoxyinositol derivatives. First example of a fagopyritol β-analogue containing an aminoinositol unit