2024-03-28T16:48:24Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/1827652021-12-27T16:42:10Zcom_10261_25com_10261_1com_10261_11773col_10261_278col_10261_11774
00925njm 22002777a 4500
dc
Valencia, Estela-Ynes
author
Espósito, Fernanda
author
Spira, Beny
author
Blázquez Gómez, Jesús
author
Galhardo, Rodrigo
author
2017-03
Resistance to antibiotics is a global health problem. Activation of the SOS response, and the subsequent elevation in mutagenesis, contributes to the appearance of resistance mutations. Among currently used drugs, quinolones are the most potent inducers of the SOS response. In the present study, we show that amikacin inhibits ciprofloxacin-mediated SOS induction and mutagenesis in Pseudomonas aeruginosa.
Antimicrobial Agents and Chemotherapy 61(3): 02107-16 (2017)
0066-4804
http://hdl.handle.net/10261/182765
10.1128/AAC.02107-16
1098-6596
http://dx.doi.org/10.13039/501100004587
http://dx.doi.org/10.13039/501100003593
http://dx.doi.org/10.13039/501100000780
http://dx.doi.org/10.13039/501100003329
http://dx.doi.org/10.13039/501100001807
28031197
Pseudomonas aeruginosa
SOS response
Ciprofloxacin
recA
Ciprofloxacin-Mediated Mutagenesis Is Suppressed by Subinhibitory Concentrations of Amikacin in Pseudomonas aeruginosa