2024-03-29T00:24:41Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/1676992020-12-13T09:03:48Zcom_10261_56com_10261_3col_10261_309
00925njm 22002777a 4500
dc
Grabchev, Ivo
author
Vasileva-Tonkova, E.
author
Staneva, Desislava
author
Bosch, Paula
author
Kukeva, R.
author
Stoyanova, R.
author
2018
A new polyamidoamine metallodendrimer modified with eight 1,8-naphthalimide units was synthesized. The Cu(II) complex has been investigated by EPR spectroscopy and it has shown that 17 copper ions have involved in the dendrimer complex. To confirm the presence of metallodendrimers on the cotton surface, scanning electron microscopy characterization has been used. In vitro antimicrobial activity of the metallodendrimer against different pathogens was investigated and compared to the dendrimer ligand free of copper ions. Both dendrimers were deposited on a cotton fabric and antibacterial activity of the treated cotton samples was investigated against model Gram-positive and Gram-negative bacteria. It has been shown that the studied dendrimers reduce bacterial growth and prevent the formation of biofilms. The metallodendrimer showed stronger antimicrobial and biofilm inhibiting abilities than those of the free of Cu(II) ions ligand.
International Journal of Polymer Analysis and Characterization 23: 45-57 (2018)
http://hdl.handle.net/10261/167699
10.1080/1023666X.2017.1387025
http://dx.doi.org/10.13039/501100003335
http://dx.doi.org/10.13039/501100010198
Antibacterial textile
SEM
Metallodendrimers
Biofilms
1,8-Naphthalimides
Synthesis, spectral characterization, and in vitro antimicrobial activity in liquid medium and applied on cotton fabric of a new PAMAM metallodendrimer