2024-03-19T05:41:29Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/1625232020-12-10T16:52:12Zcom_10261_56com_10261_3col_10261_309
00925njm 22002777a 4500
dc
Mora-Boza, Ana
author
Puertas-Bartolomé, María
author
Vázquez-Lasa, Blanca
author
San Román, Julio
author
Pérez-Caballer, Antonio
author
Olmeda-Lozano, Marta
author
2017
An overview of the most relevant crosslinking processes and agents that are being developed for regenerative medicine, including different hydrogel modifications as well as several interesting and advanced applications. The functionality and reactivity of polysaccharides and in particular hyaluronic acid in combination with proteins like gelatin, collagen and many others offer very interesting opportunities for the new trends in regenerative medicine. The biomimetic approaches for the application in regenerative processes and tissue engineering have enormous possibilities because of the excellent response of these biomimetic materials and their bioactive and biodegradable character in the human body. These characteristics together with the possibility of application by minimally invasive surgery offer very interesting applications in regeneration of tissues and organs, as well as in targeting and releasing of bioactive compounds applications as drug delivery systems. In addition, the growing of clinical applications of these macromolecular components as assemblies opens new and advanced opportunities in regenerative medicine and drug delivery fields.
European Polymer Journal 95: 11-26 (2017)
http://hdl.handle.net/10261/162523
10.1016/j.eurpolymj.2017.07.039
http://dx.doi.org/10.13039/501100010198
Contribution of bioactive hyaluronic acid and gelatin to regenerative medicine. Methodologies of gels preparation and advanced applications