2024-03-29T00:54:20Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/1318932018-10-29T14:36:06Zcom_10261_25com_10261_1col_10261_278
00925njm 22002777a 4500
dc
Nikel, Pablo I.
author
Martínez-García, Esteban
author
Lorenzo, Víctor de
author
2014-05
Much of contemporary synthetic biology research relies on the use of bacterial chassis for plugging-in and plugging-out genetic circuits and new-to-nature functionalities. However, the microorganisms that are the easiest to manipulate in the laboratory are often suboptimal for downstream industrial applications, which can involve physicochemical stress and harsh operating conditions. In this Review, we advocate the use of environmental Pseudomonas strains as model organisms that are pre-endowed with the metabolic, physiological and stress-endurance traits that are demanded by current and future synthetic biology and biotechnological needs.
Nature Reviews Microbiology, 12(5) : 368-70 (2014)
1740-1526
http://hdl.handle.net/10261/131893
10.1038/nrmicro3253
1740-1534
Synthetic biology
Biocatalysis
Chassis
Energy and redox balance
Stress resistance
Metabolic engineering
Biodegradation
Pseudomonas putida
Biotechnological domestication of pseudomonads using synthetic biology