2024-03-28T09:52:17Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/2257022021-07-06T08:49:31Zcom_10261_131com_10261_2col_10261_384
2020-12-28T14:20:14Z
urn:hdl:10261/225702
Preliminary Studies on an Innovative Bioactive Skin Soluble Beauty Mask Made by Combining Electrospinning and Dry Powder Impregnation
Teno, Jorge
Pardo-Figuerez, María
Hummel, Nancy
Bonin, Vincent
Fusco, Alessandra
Ricci, Claudio
Donnarumma, Giovanna
Coltelli, Maria-Beatrice
Danti, Serena
Lagarón Cabello, José María
Bio-Based Industries
European Commission
Pullulan
Chitin nanofibril
Glycyrrhetinic acid
Nanolignin
Antiaging
The world of cosmetics is now aiming at biobased materials which are skin-compatible and can be used to generate more sustainable beauty masks with enhanced bioactivity. This work presents, in this line of interest, the combination of two innovative technologies, namely electrospinning and dry powder impregnation, to generate biobased skin soluble electrospun pullulan carriers dry impregnated with chitin nanofibrils-nanolignin-glycyrrethinic acid (CLA) complexes, as effective biobased and skin compatible beauty masks. The scalability of the pullulan electrospun carrier and bioactive complexes impregnation were optimized and the morphology evaluated. Subsequently, skin compatibility and mask effectiveness were investigated in vitro and in vivo. The results showed that cell viability was optimal for both impregnated and neat pullulan fibers. Additionally, the CLA impregnated pullulan fibers were able to upregulate the endogenous antimicrobial molecule HBD-2. Preliminary studies in vivo indicated that the beauty mask containing the CLA complexes significantly decreased area, length and depth of forehead and crow’s feet wrinkles, and significantly increased moisturizing levels in the skin. The developed beauty mask was also seen to increase skin firmness, while it did not show skin irritation after the test. The work demonstrates that the combination of these two technologies may open new alternatives to more sustainable bioactive cosmetic products for the skin.
2020-12-28T14:20:14Z
2020-12-28T14:20:14Z
2020-12-11
2020-12-28T14:20:15Z
artículo
Cosmetics 7(4): 96 (2020)
http://hdl.handle.net/10261/225702
10.3390/cosmetics7040096
2079-9284
http://dx.doi.org/10.13039/501100000780
Publisher's version
Sí
info:eu-repo/grantAgreement/EC/H2020/745839
https://creativecommons.org/licenses/by/4.0/
openAccess
Multidisciplinary Digital Publishing Institute