2024-03-29T00:22:22Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/314152020-03-12T09:59:17Zcom_10261_28com_10261_4com_10261_10252com_10261_3col_10261_281col_10261_10253
http://hdl.handle.net/10261/31415
10.1088/0957-4484/20/33/335501
32065
Plasma-activated multi-walled carbon nanotube–polystyrene composite substrates for biosensing
Institute of Physics Publishing
2009
artículo
Fernández Sánchez, César
rp10881
Pellicer, Eva
Orozco, Jahir
Jiménez-Jorquera, Cecilia
rp05601
Lechuga, Laura M.
rp13404
Mendoza Gómez, Ernest
2009-08
7 páginas, 6 figuras, 2 tablas.-- PACS 87.80.-y Biophysical techniques (research methods)
52.77.Bn Etching and cleaning
85.35.Kt Nanotube devices
07.07.Mp Transducers
79.60.-i Photoemission and photoelectron spectra.
Carbon nanotube–polymer composites have shown to be suitable materials for the fabrication of
electrochemical transducers. The exposed surface of these materials is commonly passivated by
a very thin layer of the polymer component that buries the conductive carbon particles. Working
with multi-walled carbon nanotube–polystyrene (MWCNT–PS) composite structures, it was
previously described how a simple low power oxygen plasma process produced an effective
etching of the composite surface, thereby exposing the conductive surface of CNTs. This work
shows how this plasma process not only gave rise to a suitable composite conductive surface for
electrochemical sensing but simultaneously exposed and created a high density of
oxygen-containing functional groups at both the CNT and the PS components, without affecting
the material’s mechanical stability. These chemical groups could be effectively modified for the
stable immobilization of biological receptors. A detailed chemical characterization of the
plasma-activated composite surface was possible using x-ray photoelectron spectroscopy. The
material reactivity towards the tethering of a protein was studied and protein–protein
interactions were then evaluated on the modified composite transducers by scanning electron
microscopy. Finally, an amperometric immunosensor approach for the detection of rabbit
Immunoglobulin G target analyte was described and a minimum concentration of 3 ng ml−1
was easily measured.
Ministerio de Ciencia e Innovación (España)
Ministerio de Educación y Ciencia (España)
Consejo Superior de Investigaciones Científicas (España)
European Commission
Nanotechnology
2009
20
335501