2024-03-28T12:03:16Zhttp://digital.csic.es/dspace-oai/requestoai:digital.csic.es:10261/2169072022-10-01T04:30:49Zcom_10261_5062com_10261_5col_10261_5064
http://hdl.handle.net/10261/216907
10.1016/j.envpol.2020.114846
397645
Hydrocarbon-induced hormesis: 101 years of evidence at the margin?
Elsevier
2020
artículo
Agathokleous, Evgenios
Barceló, Damià
Tsatsakis, Aristidis
Calabrese, Edward J.
Barceló, Damià [0000-0002-8873-0491]
Environmental pollution
Dose-response relationship
Global environmental change
Hormesis
Hydrocarbon contamination
Organismic stress
2020-10
Hydrocarbons are used worldwide for an array of purposes ranging from transportation to making plastics and synthetic fibers. Hydrocarbons pollution can occur from local to global scales, becoming a focus of regulatory authorities since a long time ago. While studies show numerous adverse effects on biota, such effects usually occur at very high doses. This paper collates significant evidence showing that hydrocarbons induce hormesis in biota, with dual effects of low versus high doses. Hydrocarbon-induced hormetic responses should be considered in relevant dose-response studies as well as in risk assessment. Dismissing hormesis could lead to incorrect predictions of hydrocarbons effects, which can occur at doses up to 100 times smaller than the traditional toxicological threshold, and would raise serious concerns regarding human and ecological health safety.
Environmental Pollution 265 (Part B)
2020
114846