Vicent, Guillermo P.
Firma en Digital.CSIC (*)
Vicent, Guillermo P.
Centro o Instituto
CSIC - Instituto de Biologia Molecular de Barcelona (IBMB)
Departamento
Molecular genomics
Categoría Profesional
Research Scientist CSIC
Especialización
Guillermo Vicent obtained his PhD in Biological Sciences from the University of Buenos Aires. In 1998 he moved to the Institüt für Molekularbiologie und Tumorforschung (Marburg, Germany) as a postdoctoral fellow where he became interested in understanding the link between transcription and chromatin. In 2003 he moved to the Center for Genomic Regulation (Barcelona, Spain) where he developed his scientific career first as senior postdoc and then as staff scientist in the Gene Regulation, Stem Cells and Cancer Programme. In 2018 he obtained a position as Scientific Researcher of the Spanish Research Council. Guillermo Vicent’s research is focused on elucidate the mechanistic basis of hormone-dependent tumor proliferation in breast cancer. Using cell lines and spheroids that in the presence of estrogens and progestins proliferate and generate the expansion to stem cells with a more aggressive phenotype and with a worse prognosis, we will understand how the hormones participate and generate such drastic changes in cell identity. We pay particular attention to the cell signaling pathways, kinases, long non-coding RNAs (lncRNAs), chromatin remodeling and DNA repair machineries that may be involved in the regulation of key genes in the process of cell dedifferentiation and cancer.
Email
gvmbmc@ibmb.csic.es
ORCID
WoS ResearcherID - Publons
Scopus AuthorID