26bebbf092424f6f8fa2df626ba1d33b.jpg.200x200_q95_crop_detail_upscale.jpg picture
 
Firma en Digital.CSIC (*)
Vicent, Guillermo P.
 
Centro o Instituto
CSIC - Instituto de Biologia Molecular de Barcelona (IBMB)
 
Departamento
Molecular genomics
 
Categoría Profesional
Research Scientist CSIC
 
Especialización
Guillermo Vicent obtained his PhD in Biological Sciences from the University of Buenos Aires. In 1998 he moved to the Institüt für Molekularbiologie und Tumorforschung (Marburg, Germany) as a postdoctoral fellow where he became interested in understanding the link between transcription and chromatin. In 2003 he moved to the Center for Genomic Regulation (Barcelona, Spain) where he developed his scientific career first as senior postdoc and then as staff scientist in the Gene Regulation, Stem Cells and Cancer Programme. In 2018 he obtained a position as Scientific Researcher of the Spanish Research Council. Guillermo Vicent’s research is focused on elucidate the mechanistic basis of hormone-dependent tumor proliferation in breast cancer. Using cell lines and spheroids that in the presence of estrogens and progestins proliferate and generate the expansion to stem cells with a more aggressive phenotype and with a worse prognosis, we will understand how the hormones participate and generate such drastic changes in cell identity. We pay particular attention to the cell signaling pathways, kinases, long non-coding RNAs (lncRNAs), chromatin remodeling and DNA repair machineries that may be involved in the regulation of key genes in the process of cell dedifferentiation and cancer.
 
Email
gvmbmc@ibmb.csic.es
 
 
WoS ResearcherID - Publons
 
Scopus AuthorID
 

Results 1-5 of 5 (Search time: 0.007 seconds).

RightsPreviewIssue DateTitleAuthor(s)Type
1closedAccessaccesoRestringido.pdf.jpg16-Sep-2019C/EBPα mediates the growth inhibitory effect of progestins on breast cancer cellsNacht, A. Silvina; Ferrari, Roberto; Zaurin, Roser; Scabia, Valentina; Carbonell‐Caballero, José; Le Dily, Francois; Quilez, Javier CSIC ORCID; Leopoldi, Alexandra; Brisken, Cathrin; Beato, Miguel; Vicent, Guillermo P. CSIC ORCID artículo
2openAccessGlucocorticoid_Rocha_Preprint2020.pdf.jpg2020Glucocorticoids uncover a critical role for ASH2L on BCL-X expression regulation in leukemia cellsRocha-Viegas, Luciana; Silberminsa, Micaela; Ogara, Maria F.; Pellegrini, Joaquín Miguel; Yanel Nuñez, Sol; García, Verónica Edith; Vicent, Guillermo P. CSIC ORCID ; Pecci, Adaliartículo
3openAccess2019Hormone-control regions mediate steroid receptor–dependent genome organizationLe Dily, Francois; Vidal, Enrique; Cuartero, Yasmina; Quilez, Javier CSIC ORCID; Nacht, A. Silvina; Vicent, Guillermo P. CSIC ORCID ; Carbonell-Caballero, José; Sharma, Priyanka; Villanueva-Cañas, José Luis; Ferrari, Roberto; Llobet, Lara Isabel de; Verde, Gaetano; Wright, Roni H.G; Beato, Miguelartículo
4openAccessThe Chromatin Remodeler_CeballosChavez.pdf.jpg20-Apr-2015The Chromatin Remodeler CHD8 Is Required for Activation of Progesterone Receptor-Dependent EnhancersCeballos-Chávez, María CSIC ORCID; Subtil-Rodríguez, Alicia CSIC; Giannopoulou, Eugenia G.; Soronellas, Daniel; Vázquez-Chávez, Elena; Vicent, Guillermo P. CSIC ORCID ; Elemento, Olivier; Beato, Miguel; Reyes, José C. CSIC ORCID artículo
5openAccessGlucocorticoid_Ogara_Art2019.pdf.jpg18-Nov-2019The glucocorticoid receptor interferes with progesterone receptor-dependent genomic regulation in breast cancer cellsOgara, Maria F.; Rodríguez-Seguí, Santiago A.; Marini, Melisa; Silvina Nacht, Ana; Stortz, Martin; Levi, Valeria; Presman, Diego M.; Vicent, Guillermo P. CSIC ORCID ; Pecci, Adaliartículo