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Firma en Digital.CSIC (*)
Vicent, Guillermo P.
Centro o Instituto
CSIC - Instituto de Biologia Molecular de Barcelona (IBMB)
Molecular genomics
Categoría Profesional
Research Scientist CSIC
Guillermo Vicent obtained his PhD in Biological Sciences from the University of Buenos Aires. In 1998 he moved to the Institüt für Molekularbiologie und Tumorforschung (Marburg, Germany) as a postdoctoral fellow where he became interested in understanding the link between transcription and chromatin. In 2003 he moved to the Center for Genomic Regulation (Barcelona, Spain) where he developed his scientific career first as senior postdoc and then as staff scientist in the Gene Regulation, Stem Cells and Cancer Programme. In 2018 he obtained a position as Scientific Researcher of the Spanish Research Council. Guillermo Vicent’s research is focused on elucidate the mechanistic basis of hormone-dependent tumor proliferation in breast cancer. Using cell lines and spheroids that in the presence of estrogens and progestins proliferate and generate the expansion to stem cells with a more aggressive phenotype and with a worse prognosis, we will understand how the hormones participate and generate such drastic changes in cell identity. We pay particular attention to the cell signaling pathways, kinases, long non-coding RNAs (lncRNAs), chromatin remodeling and DNA repair machineries that may be involved in the regulation of key genes in the process of cell dedifferentiation and cancer.
WoS ResearcherID - Publons
Scopus AuthorID

Results 1-6 of 6 (Search time: 0.059 seconds).

RightsPreviewIssue DateTitleAuthor(s)Type
1openAccess16-Dec-2021A set of accessible enhancers enables the initial response of breast cancer cells to physiological progestin concentrationsZaurin, Roser; Ferrari, Roberto; Carbonell‐Caballero, José; Le Dily, Francois; Font-Mateu, Jofre; Llobet Cucalon, Lara Isabel de; Vidal, Enrique; Lioutas, Antonios; Beato, Miguel; Vicent, Guillermo P. CSIC ORCID artículo
2closedAccessaccesoRestringido.pdf.jpg16-Sep-2019C/EBPα mediates the growth inhibitory effect of progestins on breast cancer cellsNacht, Ana Silvina; Ferrari, Roberto; Zaurin, Roser; Scabia, Valentina; Carbonell‐Caballero, José; Le Dily, Francois; Quilez, Javier CSIC ORCID; Leopoldi, Alexandra; Brisken, Cathrin; Beato, Miguel; Vicent, Guillermo P. CSIC ORCID artículo
3openAccessGlucocorticoid_Rocha_Preprint2020.pdf.jpg2020Glucocorticoids uncover a critical role for ASH2L on BCL-X expression regulation in leukemia cellsRocha-Viegas, Luciana; Silberminsa, Micaela; Ogara, Maria F.; Pellegrini, Joaquín Miguel; Yanel Nuñez, Sol; García, Verónica Edith; Vicent, Guillermo P. CSIC ORCID ; Pecci, Adaliartículo
4openAccess2019Hormone-control regions mediate steroid receptor–dependent genome organizationLe Dily, Francois; Vidal, Enrique; Cuartero, Yasmina; Quilez, Javier CSIC ORCID; Nacht, A. Silvina; Vicent, Guillermo P. CSIC ORCID ; Carbonell-Caballero, José; Sharma, Priyanka; Villanueva-Cañas, José Luis CSIC ORCID CVN; Ferrari, Roberto; Llobet, Lara Isabel de; Verde, Gaetano; Wright, Roni H.G; Beato, Miguelartículo
5openAccessThe Chromatin Remodeler_CeballosChavez.pdf.jpg20-Apr-2015The Chromatin Remodeler CHD8 Is Required for Activation of Progesterone Receptor-Dependent EnhancersCeballos-Chávez, María CSIC ORCID; Subtil-Rodríguez, Alicia CSIC; Giannopoulou, Eugenia G.; Soronellas, Daniel; Vázquez-Chávez, Elena; Vicent, Guillermo P. CSIC ORCID ; Elemento, Olivier; Beato, Miguel; Reyes, José C. CSIC ORCID artículo
6openAccessGlucocorticoid_Ogara_Art2019.pdf.jpg18-Nov-2019The glucocorticoid receptor interferes with progesterone receptor-dependent genomic regulation in breast cancer cellsOgara, Maria F.; Rodríguez-Seguí, Santiago A.; Marini, Melisa; Nacht, Ana Silvina; Stortz, Martin; Levi, Valeria; Presman, Diego M.; Vicent, Guillermo P. CSIC ORCID ; Pecci, Adaliartículo