1. DIGITAL.CSIC

Abad, José Luis

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Perfil

dr-jose-luis-abad-rubam.jpg picture
 
Firma en Digital.CSIC (*)
Abad, José Luis
 
Centro o Instituto
CSIC - Instituto de Quimica Avanzada de Cataluña (IQAC)
 
Categoría Profesional
Senior Research Scientist
 
Especialización
Jose Luis Abad obtanied a Master’s degree in Organic Chemist in 1991 and a PhD from the University of Barcelona (UB) in 1995 in the field of the bioorganic chemistry of steroidogenesis. Then he joined the group of Prof. Roger A. Jones (Rutgers University, NJ, USA) where he worked on the synthesis and applications of mass labelled nucleotides. After three years at Rutgers, he returned to the CSIC and worked on the synthesis and use of stereospecifically deuterated fatty acids to decipher mechanistic aspects of acyl-CoA desaturase reactions. After becoming a staff member of CSIC, he focused on the synthesis of sphingolipid analogues. His research interests include the synthesis by both chemical and enzymatic methods of masslabelled lipids and lipid analogues for structural and biological studies. He is also interested in the development of synthetic methodology for the stereocontrolled synthesis of sphingolipid modulators and chemical probes.
 
Email
jlaqob@iqac.csic.es
 
ORCID
 
WoS ResearcherID - Publons
 
Scopus AuthorID
 

Publications

Refined By:
Palabras Clave:  Ceramide

Resultados 1-6 de 6.

DerechosPreviewFecha Public.TítuloAutor(es)Tipo
1closedAccessaccesoRestringido.pdf.jpg19-feb-2013Acid ceramidase as a therapeutic target in metastatic prostate cancerCamacho, Luz CSIC ORCID; Meca-Cortés, Óscar CSIC ORCID; Abad, José Luis CSIC ORCID ; García, Simón CSIC; Rubio, Nuria CSIC; Celià-Terrassa, Toni CSIC ORCID; Cingolani, Francesca CSIC; Blanco, Jerónimo CSIC ORCID; Delgado Cirilo, Antonio CSIC ORCID; Casas, Josefina CSIC ORCID ; Thomson, Timothy M. CSIC ORCID artículo
2openAccessChemotherapy selection pressure alters sphingolipid composition and mitochondrial bioenergeticsin.pdf.jpgjul-2019Chemotherapy selection pressure alters sphingolipid composition and mitochondrial bioenergeticsin resistant HL-60 cellsLi-Pin Kao; Morad, Samy A.F.; Davis, Traci S.; MacDougall, Matthew R.; Kassai, Miki; Abdelmageed, Noha; Fox, Todd E.; Kester, Mark; Loughran Jr. Thomas P.; Abad, José Luis CSIC ORCID ; Fabriàs, Gemma CSIC ORCID ; Faith, David J.; Su-Fern Tan; Claxton, David F.; Spiegel, Sarah; Fisher-Wellman, Kelsey H.; Cabot, Myles C.artículo
3openAccess#EJMC_revised final UNmarked.pdf.jpg24-feb-2021Discovery of deoxyceramide analogs as highly selective ACER3 inhibitors in live cellsBielsa, Núria; Casasampere, Mireia CSIC ORCID; Aseeri, Mazen; Casas, Josefina CSIC ORCID ; Delgado Cirilo, Antonio CSIC ORCID; Abad, José Luis CSIC ORCID ; Fabriàs, Gemma CSIC ORCID artículo
4openAccessHigh throughput discovery of novel small molecule inhibitors of acid Ceramidase.pdf.jpgdic-2023High-throughput discovery of novel small-molecule inhibitors of acid CeramidaseAseeri, Mazen; Abad, José Luis CSIC ORCID ; Delgado Cirilo, Antonio CSIC ORCID; Fabriàs, Gemma CSIC ORCID; Triola, Gemma; Casas, Josefina CSIC ORCID artículo
5openAccess1-jul-2017Inhibitors of ceramide de novo biosynthesis rescue damages induced by cigarette smoke in airways epitheliaZulueta, Aida; Caretti, Anna; Campisi, Giuseppe Matteo; Brizzolari, Andrea; Abad, José Luis CSIC ORCID ; Paroni, R.; Signorelli, Paola; Ghidoni, Riccardoartículo
6openAccesscancers-15-01883.pdf.jpg21-mar-2023Simultaneous Inhibition of Ceramide Hydrolysis and Glycosylation Synergizes to Corrupt Mitochondrial Respiration and Signal Caspase Driven Cell Death in Drug-Resistant Acute Myeloid LeukemiaFisher-Wellman, Kelsey H.; Kassai, Miki; Hagen, James T.; Neufer, P Darrell; Kester, Mark; Loughran, Thomas P.; Chalfant, Charles E.; Feith, David J.; Tan, Su-Fern; Fox, Todd E.; Ung, Johnson; Fabriàs, Gemma CSIC ORCID ; Abad, José Luis CSIC ORCID ; Sharma, Arati; Golla, Upendarrao; Claxton, David F.; Shaw, Jeremy J. P.; Bhowmick, Debajit; Cabot, Myles C.artículo