1. DIGITAL.CSIC

Abad, José Luis

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Perfil

dr-jose-luis-abad-rubam.jpg picture
 
Firma en Digital.CSIC (*)
Abad, José Luis
 
Centro o Instituto
CSIC - Instituto de Quimica Avanzada de Cataluña (IQAC)
 
Categoría Profesional
Senior Research Scientist
 
Especialización
Jose Luis Abad obtanied a Master’s degree in Organic Chemist in 1991 and a PhD from the University of Barcelona (UB) in 1995 in the field of the bioorganic chemistry of steroidogenesis. Then he joined the group of Prof. Roger A. Jones (Rutgers University, NJ, USA) where he worked on the synthesis and applications of mass labelled nucleotides. After three years at Rutgers, he returned to the CSIC and worked on the synthesis and use of stereospecifically deuterated fatty acids to decipher mechanistic aspects of acyl-CoA desaturase reactions. After becoming a staff member of CSIC, he focused on the synthesis of sphingolipid analogues. His research interests include the synthesis by both chemical and enzymatic methods of masslabelled lipids and lipid analogues for structural and biological studies. He is also interested in the development of synthetic methodology for the stereocontrolled synthesis of sphingolipid modulators and chemical probes.
 
Email
jlaqob@iqac.csic.es
 
ORCID
 
WoS ResearcherID - Publons
 
Scopus AuthorID
 

Publications

Refined By:
Autor:  Abad, José Luis

Resultados 1-20 de 51.

DerechosPreviewFecha Public.TítuloAutor(es)Tipo
1openAccessC5MB00852B_postprint.pdf.jpg22-abr-20163-Ketosphinganine provokes the accumulation of dihydroshingolipids and induces autophagy in cancer cells.Ordóñez, Yadira F.; González, Jèssica; Bedia, Carmen CSIC ORCID; Casas, Josefina CSIC ORCID ; Abad, José Luis CSIC ORCID ; Delgado Cirilo, Antonio CSIC ORCID; Fabriàs, Gemma CSIC ORCID artículo
2openAccessmar-2024A fluorogenic substrate for the detection of lipid amidases in intact cellsCasasampere, Mireia CSIC ORCID; Ung, Johnson; Iñáñez, Alejandro; Dufau, Carine; Tsuboi, Kazuhito; Casas, Josefina CSIC ORCID ; Tan, Su-Fern; Feith, David J.; Andrieu-Abadie, Nathalie; Segui, Bruno; Loughran, Thomas P.; Abad, José Luis CSIC ORCID ; Fabriàs, Gemma CSIC ORCID artículo
3openAccessA Mechanism-Based Sphingosine-1-phosphate Lyase Inhibitor.pdf.jpg17-ene-2020A Mechanism-Based Sphingosine-1-phosphate Lyase InhibitorPons, Guillem; Riba, Daniel; Casasampere, Mireia CSIC ORCID; Izquierdo, Eduardo; Abad, José Luis CSIC ORCID ; Fabriàs, Gemma CSIC ORCID ; Rodríguez Ortega, Pilar G.; Montejo, Manuel; López González, Juan J.; Casas, Josefina CSIC ORCID ; Delgado Cirilo, Antonio CSIC ORCIDartículo
4closedAccess2010A simple fluorogenic method for determination of acid ceramidase activity and diagnosis of Farber diseaseBedia, Carmen CSIC ORCID; Camacho, Luz CSIC ORCID; Abad, José Luis CSIC ORCID ; Fabriàs, Gemma CSIC ORCID ; Levade, Thierryartículo
5closedAccessaccesoRestringido.pdf.jpg19-feb-2013Acid ceramidase as a therapeutic target in metastatic prostate cancerCamacho, Luz CSIC ORCID; Meca-Cortés, Óscar CSIC ORCID; Abad, José Luis CSIC ORCID ; García, Simón CSIC; Rubio, Nuria CSIC; Celià-Terrassa, Toni CSIC ORCID; Cingolani, Francesca CSIC; Blanco, Jerónimo CSIC ORCID; Delgado Cirilo, Antonio CSIC ORCID; Casas, Josefina CSIC ORCID ; Thomson, Timothy M. CSIC ORCID artículo
6openAccessActivity of neutral and alkaline ceramidases on fluorogenic N -acylated coumarin-containing aminodiols.pdf.jpg1-oct-2015Activity of neutral and alkaline ceramidases on fluorogenic N -acylated coumarin-containing aminodiolsCasasampere, Mireia CSIC ORCID; Camacho, Luz CSIC ORCID; Casas, Josefina CSIC ORCID ; Cingolani, Francesca CSIC; Egido-Gabás, Meritxell CSIC; Abad, José Luis CSIC ORCID ; Bedia, Carmen CSIC ORCID; Fabriàs, Gemma CSIC ORCID artículo
7openAccess28-abr-2019Activity-Based Imaging of Acid Ceramidase in Living CellsOrdóñez, Yadira F.; Abad, José Luis CSIC ORCID ; Aseeri, Mazen; Casas, Josefina CSIC ORCID ; Garcia, Virginie; Casasampere, Mireia CSIC ORCID; Schuchman, Edward H.; Levade, Thierry; Delgado Cirilo, Antonio CSIC ORCID; Triola Guillem, Gemma CSIC ORCID; Fabriàs, Gemma CSIC ORCID artículo
8closedAccess2010An Unexpected Access to a New Sphingoid Base Containing a Vinyl Sulfide UnitNieves, Ingrid CSIC; Garrido, María CSIC; Abad, José Luis CSIC ORCID ; Delgado Cirilo, Antonio CSIC ORCIDartículo
9openAccessAnalysis of the neurotoxic effects of neuropathic organophosphorus compounds in adult zebrafish.pdf.jpg1-dic-2018Analysis of the neurotoxic effects of neuropathic organophosphorus compounds in adult zebrafishFaria, Melissa CSIC ORCID; Fuertes, Inmaculada CSIC ORCID; Prats, Eva CSIC ORCID ; Abad, José Luis CSIC ORCID ; Padrós, Francesc; Gómez-Canela, Cristian CSIC ORCID; Casas, Josefina CSIC ORCID ; Estévez, Jorge; Vilanova, Eugenio; Piña, Benjamín CSIC ORCID ; Raldúa, Demetrio CSIC ORCID artículo
10openAccessAbad_Jose_Luis_et_al.pdf.jpg8-oct-2004Arylacetic acid derivatization of 2,3- and internal erythro-squalene diols. Separation and absolute configuration determinationAbad, José Luis CSIC ORCID ; Camps Díez, Francisco CSICartículo
11openAccessAzide-tagged Sphingolipids.pdf.jpg12-nov-2018Azide-tagged sphingolipids for the proteome-wide identification of C16-ceramide-binding proteinsSchulte-Zweckel, Janine; Schneidewind, Tabea; Abad, José Luis CSIC ORCID ; Brockmeyer, Andreas; Janning, Petra; Triola Guillem, Gemma CSIC ORCIDartículo
12openAccess1-s2.0-S0022202X15354865-main.pdf.jpg2012Cellular changes that accompany shedding of human corneocytesLin, T.-K.; Crumrine, D.; Ackerman, L.D.; Santiago, J.-L.; Roelandt, T.; Uchida, Y.; Hupe, M.; Fabriàs, Gemma CSIC ORCID ; Abad, José Luis CSIC ORCID ; Rice, R.H.; Elias, P.M.artículo
13closedAccess2011Ceramidases in hematological malignancies: senseless or neglected target?Fabriàs, Gemma CSIC ORCID ; Bedia, Carmen CSIC ORCID; Casas, Josefina CSIC ORCID ; Abad, José Luis CSIC ORCID ; Delgado Cirilo, Antonio CSIC ORCIDartículo
14openAccessCeramide Analogue SACLAC Modulates Sphingolipid Levels and MCL-1 Splicing to Induce Apoptosis in Acute Myeloid Leukemia .pdf.jpgmar-2020Ceramide Analogue SACLAC Modulates Sphingolipid Levels and MCL-1 Splicing to Induce Apoptosis in Acute Myeloid LeukemiaPearson, Jennifer M.; Tan, Su-Fern; Sharma, Arati; Annageldiyev, Charyguly; Fox, Todd E.; Abad, José Luis CSIC ORCID ; Fabriàs, Gemma CSIC ORCID ; Desai, Dhimant; Amin, Shantu; Wang, Hong-Gang; Cabot, Myles C.; Claxton, David F.; Kester, Mark; Feith, David J.; Loughran, Thomas P.artículo
15closedAccess25-jun-2007Chemical tools to investigate sphingolipid metabolism and functionsDelgado Cirilo, Antonio CSIC ORCID; Casas, Josefina CSIC ORCID ; Llebaria, Amadeu CSIC ORCID; Abad, José Luis CSIC ORCID ; Fabriàs, Gemma CSIC ORCID artículo
16openAccessChemotherapy selection pressure alters sphingolipid composition and mitochondrial bioenergeticsin.pdf.jpgjul-2019Chemotherapy selection pressure alters sphingolipid composition and mitochondrial bioenergeticsin resistant HL-60 cellsLi-Pin Kao; Morad, Samy A.F.; Davis, Traci S.; MacDougall, Matthew R.; Kassai, Miki; Abdelmageed, Noha; Fox, Todd E.; Kester, Mark; Loughran Jr. Thomas P.; Abad, José Luis CSIC ORCID ; Fabriàs, Gemma CSIC ORCID ; Faith, David J.; Su-Fern Tan; Claxton, David F.; Spiegel, Sarah; Fisher-Wellman, Kelsey H.; Cabot, Myles C.artículo
17openAccess1-s2.0-S1386142521011082-main.pdf.jpg15-feb-2022Chirality-Puckering correlation and intermolecular interactions in Sphingosines: Rotational spectroscopy of jaspine B3 and its monohydrateSaragi, Rizalina T.; Juanes, Marcos; Abad, José Luis CSIC ORCID ; Pinacho, Ruth; Rubio, José E.; Lesarri, Albertoartículo
18openAccessd0sc03166f.pdf.jpg22-oct-2020Click and Count: Specific Detection of Acid Ceramidase Activity in Live CellsCasasampere, Mireia CSIC ORCID; Izquierdo, Eduardo; Casas, Josefina CSIC ORCID ; Abad, José Luis CSIC ORCID ; Liu, Xiao; Xu, Ruijuan; Mao, Cungui; Chang, Young-Tae; Delgado Cirilo, Antonio CSIC ORCID; Fabriàs, Gemma CSIC ORCID artículo
19closedAccess2010Control of metabolism and signaling of simple bioactive sphingolipids: Implications in diseaseGangoiti, Patricia; Camacho, Luz CSIC ORCID; Arana, Lide CSIC ORCID; Ouro, Alberto; Granado, María H.; Brizuela, Leyre; Casas, Josefina CSIC ORCID ; Fabriàs, Gemma CSIC ORCID ; Abad, José Luis CSIC ORCID ; Delgado Cirilo, Antonio CSIC ORCID; Gómez-Muñoz, Antonioartículo
20closedAccessaccesoRestringido.pdf.jpg2004Dedifferentiated adult articular chondrocytes: A population of human multipotent primitive cellsFuente, Ricardo de la; Abad, José Luis CSIC ORCID ; García-Castro, Javier; Fernández-Miguel, Gemma CSIC; Petriz, Jordi; Rubio, Daniel; Vicario-Abejón, Carlos CSIC ORCID ; Guillén, Pedro; González, Manuel A.; Bernad, Antonio CSIC ORCIDartículo