dr-jose-luis-abad-rubam.jpg picture
 
Firma en Digital.CSIC (*)
Abad, José Luis
 
Centro o Instituto
CSIC - Instituto de Quimica Avanzada de Cataluña (IQAC)
 
Categoría Profesional
Senior Research Scientist
 
Especialización
Jose Luis Abad obtanied a Master’s degree in Organic Chemist in 1991 and a PhD from the University of Barcelona (UB) in 1995 in the field of the bioorganic chemistry of steroidogenesis. Then he joined the group of Prof. Roger A. Jones (Rutgers University, NJ, USA) where he worked on the synthesis and applications of mass labelled nucleotides. After three years at Rutgers, he returned to the CSIC and worked on the synthesis and use of stereospecifically deuterated fatty acids to decipher mechanistic aspects of acyl-CoA desaturase reactions. After becoming a staff member of CSIC, he focused on the synthesis of sphingolipid analogues. His research interests include the synthesis by both chemical and enzymatic methods of masslabelled lipids and lipid analogues for structural and biological studies. He is also interested in the development of synthetic methodology for the stereocontrolled synthesis of sphingolipid modulators and chemical probes.
 
Email
jlaqob@iqac.csic.es
 
 
WoS ResearcherID - Publons
 
Scopus AuthorID
 

Publications

Refined By:
Autor:  Casasampere, Mireia

Resultados 1-10 de 10.

DerechosPreviewFecha Public.TítuloAutor(es)Tipo
1openAccessmar-2024A fluorogenic substrate for the detection of lipid amidases in intact cellsCasasampere, Mireia CSIC ORCID; Ung, Johnson; Iñáñez, Alejandro; Dufau, Carine; Tsuboi, Kazuhito; Casas, Josefina CSIC ORCID ; Tan, Su-Fern; Feith, David J.; Andrieu-Abadie, Nathalie; Segui, Bruno; Loughran, Thomas P.; Abad, José Luis CSIC ORCID ; Fabriàs, Gemma CSIC ORCID artículo
2openAccessA Mechanism-Based Sphingosine-1-phosphate Lyase Inhibitor.pdf.jpg17-ene-2020A Mechanism-Based Sphingosine-1-phosphate Lyase InhibitorPons, Guillem; Riba, Daniel; Casasampere, Mireia CSIC ORCID; Izquierdo, Eduardo; Abad, José Luis CSIC ORCID ; Fabriàs, Gemma CSIC ORCID ; Rodríguez Ortega, Pilar G.; Montejo, Manuel; López González, Juan J.; Casas, Josefina CSIC ORCID ; Delgado Cirilo, Antonio CSIC ORCIDartículo
3openAccessActivity of neutral and alkaline ceramidases on fluorogenic N -acylated coumarin-containing aminodiols.pdf.jpg1-oct-2015Activity of neutral and alkaline ceramidases on fluorogenic N -acylated coumarin-containing aminodiolsCasasampere, Mireia CSIC ORCID; Camacho, Luz CSIC ORCID; Casas, Josefina CSIC ORCID ; Cingolani, Francesca CSIC; Egido-Gabás, Meritxell CSIC; Abad, José Luis CSIC ORCID ; Bedia, Carmen CSIC ORCID; Fabriàs, Gemma CSIC ORCID artículo
4openAccess28-abr-2019Activity-Based Imaging of Acid Ceramidase in Living CellsOrdóñez, Yadira F.; Abad, José Luis CSIC ORCID ; Aseeri, Mazen; Casas, Josefina CSIC ORCID ; Garcia, Virginie; Casasampere, Mireia CSIC ORCID; Schuchman, Edward H.; Levade, Thierry; Delgado Cirilo, Antonio CSIC ORCID; Triola Guillem, Gemma CSIC ORCID; Fabriàs, Gemma CSIC ORCID artículo
5openAccessd0sc03166f.pdf.jpg22-oct-2020Click and Count: Specific Detection of Acid Ceramidase Activity in Live CellsCasasampere, Mireia CSIC ORCID; Izquierdo, Eduardo; Casas, Josefina CSIC ORCID ; Abad, José Luis CSIC ORCID ; Liu, Xiao; Xu, Ruijuan; Mao, Cungui; Chang, Young-Tae; Delgado Cirilo, Antonio CSIC ORCID; Fabriàs, Gemma CSIC ORCID artículo
6openAccess#EJMC_revised final UNmarked.pdf.jpg24-feb-2021Discovery of deoxyceramide analogs as highly selective ACER3 inhibitors in live cellsBielsa, Núria; Casasampere, Mireia CSIC ORCID; Aseeri, Mazen; Casas, Josefina CSIC ORCID ; Delgado Cirilo, Antonio CSIC ORCID; Abad, José Luis CSIC ORCID ; Fabriàs, Gemma CSIC ORCID artículo
7openAccessJaspine B induces nonapoptotic cell death in gastric cancer cells independently of its inhibition of ceramide synthase.pdf.jpgago-2017Jaspine B induces nonapoptotic cell death in gastric cancer cells independently of its inhibition of ceramide synthaseCingolani, Francesca CSIC; Simbari, Fabio CSIC; Abad, José Luis CSIC ORCID ; Casasampere, Mireia CSIC ORCID; Fabriàs, Gemma CSIC ORCID ; Futerman, Anthony H.; Casas, Josefina CSIC ORCID artículo
8openAccessijms-23-07257-v2.pdf.jpg29-jun-2022Methuosis Contributes to Jaspine-B-Induced Cell DeathBielsa, Núria; Casasampere, Mireia CSIC ORCID; Abad, José Luis CSIC ORCID ; Enrich, Carlos; Delgado Cirilo, Antonio CSIC ORCID; Fabriàs, Gemma CSIC ORCID ; Lizcano, José M.; Casas, Josefina CSIC ORCID artículo
9openAccessNew fluorogenic probes for neutral and alkaline ceramidases-preprint version.pdf.jpg29-mar-2019New fluorogenic probes for neutral and alkaline ceramidasesCasasampere, Mireia CSIC ORCID; Bielsa, Núria; Riba, Daniel; Bassas, Laura; Ruijuan, Xu; Cungui, Mao; Fabriàs, Gemma CSIC ORCID ; Abad, José Luis CSIC ORCID ; Delgado Cirilo, Antonio CSIC ORCID; Casas, Josefina CSIC ORCID artículo
10openAccessd1ob00113b.pdf.jpg23-feb-2021Synthesis and characterization of bichromophoric 1-deoxyceramides as FRET probesIzquierdo, Eduardo; Casasampere, Mireia CSIC ORCID; Fabriàs, Gemma CSIC ORCID ; Abad, José Luis CSIC ORCID ; Casas, Josefina CSIC ORCID ; Delgado Cirilo, Antonio CSIC ORCIDartículo