dr-jose-luis-abad-rubam.jpg picture
 
Firma en Digital.CSIC (*):
Abad, José Luis
 
Centro o Instituto:
CSIC - Instituto de Quimica Avanzada de Cataluña (IQAC)
 
Categoría Profesional:
Senior Research Scientist
 
Especialización:
Jose Luis Abad obtanied a Master’s degree in Organic Chemist in 1991 and a PhD from the University of Barcelona (UB) in 1995 in the field of the bioorganic chemistry of steroidogenesis. Then he joined the group of Prof. Roger A. Jones (Rutgers University, NJ, USA) where he worked on the synthesis and applications of mass labelled nucleotides. After three years at Rutgers, he returned to the CSIC and worked on the synthesis and use of stereospecifically deuterated fatty acids to decipher mechanistic aspects of acyl-CoA desaturase reactions. After becoming a staff member of CSIC, he focused on the synthesis of sphingolipid analogues. His research interests include the synthesis by both chemical and enzymatic methods of masslabelled lipids and lipid analogues for structural and biological studies. He is also interested in the development of synthetic methodology for the stereocontrolled synthesis of sphingolipid modulators and chemical probes.
 
Email:
jlaqob@iqac.csic.es
 
 
WoS ResearcherID - Publons:
 
Scopus AuthorID:
 

Results 1-20 of 43 (Search time: 0.001 seconds).

RightsPreviewIssue DateTitleAuthor(s)Type
1openAccessC5MB00852B_postprint.pdf.jpg22-Apr-20163-Ketosphinganine provokes the accumulation of dihydroshingolipids and induces autophagy in cancer cells.Ordoñez, Yadira F.; González, Jèssica; Bedia, Carmen CSIC ORCID; Casas, Josefina CSIC ORCID ; Abad, José Luis CSIC ORCID ; Delgado Cirilo, Antonio; Fabriàs, Gemma CSIC ORCIDartículo
2openAccessA Mechanism-Based Sphingosine-1-phosphate Lyase Inhibitor.pdf.jpg17-Jan-2020A Mechanism-Based Sphingosine-1-phosphate Lyase InhibitorPons, Guillem; Riba, Daniel; Casasampere, Mireia; Izquierdo, Eduardo; Abad, José Luis CSIC ORCID ; Fabriàs, Gemma CSIC ORCID; Rodríguez Ortega, Pilar G.; Montejo, Manuel; López González, Juan J.; Casas, Josefina CSIC ORCID ; Delgado Cirilo, Antonioartículo
3closedAccess2010A simple fluorogenic method for determination of acid ceramidase activity and diagnosis of Farber diseaseBedia, Carmen CSIC ORCID; Camacho, Luz CSIC ORCID; Abad, José Luis CSIC ORCID ; Fabriàs, Gemma CSIC ORCID; Levade, Thierryartículo
4closedAccessaccesoRestringido.pdf.jpg19-Feb-2013Acid ceramidase as a therapeutic target in metastatic prostate cancerCamacho, Luz CSIC ORCID; Meca-Cortés, Óscar CSIC ORCID; Abad, José Luis CSIC ORCID ; García, Simón; Rubio, Nuria; Celià-Terrassa, Toni CSIC ORCID; Cingolani, Francesca; Blanco, Jerónimo CSIC ORCID; Delgado Cirilo, Antonio; Casas, Josefina CSIC ORCID ; Thomson, Timothy M. CSIC ORCID artículo
5openAccessActivity of neutral and alkaline ceramidases on fluorogenic N -acylated coumarin-containing aminodiols.pdf.jpg1-Oct-2015Activity of neutral and alkaline ceramidases on fluorogenic N -acylated coumarin-containing aminodiolsCasasampere, Mireia; Camacho, Luz CSIC ORCID; Casas, Josefina CSIC ORCID; Cingolani, Francesca; Egido-Gabás, Meritxell CSIC; Abad, José Luis CSIC ORCID ; Bedia, Carmen CSIC ORCID; Fabriàs, Gemma CSIC ORCIDartículo
6openAccess28-Apr-2019Activity-Based Imaging of Acid Ceramidase in Living CellsOrdóñez, Yadira F.; Abad, José Luis CSIC ORCID ; Aseeri, Mazen; Casas, Josefina CSIC ORCID ; Garcia, Virginie; Casasampere, Mireia; Schuchman, Edward H.; Levade, Thierry; Delgado Cirilo, Antonio; Triola Guillem, Gemma CSIC ORCID; Fabriàs, Gemma CSIC ORCIDartículo
7closedAccess2010An Unexpected Access to a New Sphingoid Base Containing a Vinyl Sulfide UnitNieves, Ingrid; Garrido, María; Abad, José Luis CSIC ORCID ; Delgado Cirilo, Antonioartículo
8openAccessAnalysis of the neurotoxic effects of neuropathic organophosphorus compounds in adult zebrafish.pdf.jpg1-Dec-2018Analysis of the neurotoxic effects of neuropathic organophosphorus compounds in adult zebrafishFaria, Melissa CSIC ORCID CVN; Fuertes, Inmaculada; Prats, Eva CSIC ORCID ; Abad, José Luis CSIC ORCID ; Padrós, Francesc; Gómez-Canela, Cristian CSIC ORCID; Casas, Josefina CSIC ORCID ; Estévez, Jorge; Vilanova, Eugenio; Piña, Benjamín CSIC ORCID ; Raldúa, Demetrio CSIC ORCID artículo
9openAccessAbad_Jose_Luis_et_al.pdf.jpg8-Oct-2004Arylacetic acid derivatization of 2,3- and internal erythro-squalene diols. Separation and absolute configuration determinationAbad, José Luis CSIC ORCID ; Camps Díez, Franciscoartículo
10openAccessAzide-tagged Sphingolipids Sup. Material.pdf.jpg12-Nov-2018Azide-tagged sphingolipids for the proteome-wide identification of C16-ceramide-binding proteinsSchulte-Zweckel, Janine; Schneidewind, Tabea; Abad, José Luis CSIC ORCID ; Brockmeyer, Andreas; Janning, Petra; Triola Guillem, Gemma CSIC ORCIDartículo
11openAccess1-s2.0-S0022202X15354865-main.pdf.jpg2012Cellular changes that accompany shedding of human corneocytesLin, T.-K.; Crumrine, D.; Ackerman, L.D.; Santiago, J.-L.; Roelandt, T.; Uchida, Y.; Hupe, M.; Fabriàs, Gemma CSIC ORCID; Abad, José Luis CSIC ORCID ; Rice, R.H.; Elias, P.M.artículo
12closedAccess2011Ceramidases in hematological malignancies: senseless or neglected target?Fabriàs, Gemma CSIC ORCID; Bedia, Carmen CSIC ORCID; Casas, Josefina CSIC ORCID ; Abad, José Luis CSIC ORCID ; Delgado Cirilo, Antonioartículo
13openAccessCeramide analog SACLAC modulates sphingolipid levels and Mcl-1 splicing topdf.pdf.jpgMar-2020Ceramide Analogue SACLAC Modulates Sphingolipid Levels and MCL-1 Splicing to Induce Apoptosis in Acute Myeloid LeukemiaPearson, Jennifer M.; Tan, Su-Fern; Sharma, Arati; Annageldiyev, Charyguly; Fox, Todd E.; Abad, José Luis CSIC ORCID ; Fabriàs, Gemma CSIC ORCID; Desai, Dhimant; Amin, Shantu; Wang, Hong-Gang; Cabot, Myles C.; Claxton, David F.; Kester, Mark; Feith, David J.; Loughran, Thomas P.artículo
14closedAccess25-Jun-2007Chemical tools to investigate sphingolipid metabolism and functionsDelgado Cirilo, Antonio; Casas, Josefina CSIC ORCID ; Llebaria, Amadeu CSIC ORCID; Abad, José Luis CSIC ORCID ; Fabriàs, Gemma CSIC ORCIDartículo
15openAccessChemotherapy selection pressure alters sphingolipid composition and mitochondrial bioenergeticsin.pdf.jpgJul-2019Chemotherapy selection pressure alters sphingolipid composition and mitochondrial bioenergeticsin resistant HL-60 cellsLi-Pin Kao; Morad, Samy A.F.; Davis, Traci S.; MacDougall, Matthew R.; Kassai, Miki; Abdelmageed, Noha; Fox, Todd E.; Kester, Mark; Loughran Jr. Thomas P.; Abad, José Luis CSIC ORCID ; Fabriàs, Gemma CSIC ORCID; Faith, David J.; Su-Fern Tan; Claxton, David F.; Spiegel, Sarah; Fisher-Wellman, Kelsey H.; Cabot, Myles C.artículo
16openAccessd0sc03166f.pdf.jpg22-Oct-2020Click and Count: Specific Detection of Acid Ceramidase Activity in Live CellsCasasampere, Mireia; Izquierdo, Eduardo; Casas, Josefina CSIC ORCID ; Abad, José Luis CSIC ORCID ; Liu, Xiao; Xu, Ruijuan; Mao, Cungui; Chang, Young-Tae; Delgado Cirilo, Antonio; Fabriàs, Gemma CSIC ORCIDartículo
17closedAccess2010Control of metabolism and signaling of simple bioactive sphingolipids: Implications in diseaseGangoiti, Patricia; Camacho, Luz CSIC ORCID; Arana, Lide; Ouro, Alberto; Granado, María H.; Brizuela, Leyre; Casas, Josefina CSIC ORCID ; Fabriàs, Gemma CSIC ORCID; Abad, José Luis CSIC ORCID ; Delgado Cirilo, Antonio; Gómez-Muñoz, Antonioartículo
18closedAccessaccesoRestringido.pdf.jpg2004Dedifferentiated adult articular chondrocytes: A population of human multipotent primitive cellsFuente, Ricardo de la; Abad, José Luis CSIC ORCID ; García-Castro, Javier; Fernández-Miguel, Gemma; Petriz, Jordi; Rubio, Daniel; Vicario-Abejón, Carlos CSIC ORCID ; Guillén, Pedro; González, Manuel A.; Bernad, Antonioartículo
19openAccessDefinition_Toran_PV_Art2019.pdf.jpg2019Definition of a cell surface signature for human cardiac progenitor cells after comprehensive comparative transcriptomic and proteomic characterizationTorán, José Luis; López, Juan Antonio; Gomes-Alves, Patricia; Aguilar, Susana; Torroja, Carlos CSIC ORCID; Trevisan-Herraz, Marco; Moscoso, Isabel; Sebastião, Maria João; Serra, Margarida; Brito, Catarina; Cruz, Francisco Miguel; Sepúlveda, Juan Carlos; Abad, José Luis CSIC ORCID ; Galán-Arriola, Carlos; Ibáñez, Borja; Martínez, Fernando CSIC ORCID; Fernández, María Eugenia; Fernández-Avilés, Francisco; Palacios, Itziar CSIC; Borlado, Luis R.; Vázquez, Jesús CSIC ORCID CVN; Alves, Paula M.; Bernad, Antonioartículo
20closedAccess28-Feb-2006Detection of DNA Adducts Derived from the Reactive Metabolite of Furan cis-2-Butene-1,4-diaByrns, Michael C.; Vu, Choua C.; Neidigh, Jonathan W.; Abad, José Luis CSIC ORCID ; Jones, Roger A.; Peterson, Lisa A.artículo