1. DIGITAL.CSIC

Díaz, José Fernando

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Perfil

FerCIB.jpg picture
 
Firma en Digital.CSIC (*)
Díaz, José Fernando
 
Centro o Instituto
CSIC - Centro de Investigaciones Biologicas Margarita Salas (CIB)
 
Departamento
Biología Estructural y Química
 
Especialización
Agentes estabilizantes de microtúbulos
 
Email
fer@cib.csic.es
 
ORCID
 
WoS ResearcherID - Publons
 
Scopus AuthorID
 

Publications

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Fecha de Publicación:  [2000 TO 2025]

Resultados 1-20 de 130.

DerechosPreviewFecha Public.TítuloAutor(es)Tipo
1openAccessNature Communications_Menchon_2018.pdf.jpg29-may-2018A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulinMenchon, Grégory; Lucena-Agell, Daniel CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Steinmetz, Michel O.artículo
2closedAccessaccesoRestringido.pdf.jpg12-oct-2020A method for the stereoselective construction of the hemiaminal center in zampanolidesBrütsch, Tobias M.; Berardozzi, Simone; Rothe, Marlene L.; Redondo-Horcajo, Mariano CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Altmann, Karl-Heinzartículo
3openAccesstubulin_binding_Coderch.pdf.jpgmar-2013A structure-based design of new C2- and C13-substituted taxanes: Tubulin binding affinities and extended quantitative structure-activity relationships using comparative binding energy (COMBINE) analysisCoderch, Claire; Tang, Yong; Klett, Javier CSIC ORCID; Zhang, Shu-En; Ma, Yung-Tao; Shaorong, Wang; Matesanz, Ruth CSIC ; Pera, Benet CSIC; Canales, Ángeles CSIC ORCID; Jiménez-Barbero, Jesús CSIC ORCID; Morreale, Antonio; Díaz, José Fernando CSIC ORCID ; Fang, Wei-shuo S.; Gago, Federico CSIC ORCIDartículo
4openAccessJ. Biol. Chem.-2001-D__az-17307-15.pdf.jpg18-may-2001Activation of cell division protein FtsZ. Control of switch loop T3 conformation by the nucleotide gamma-phosphateDíaz, José Fernando CSIC ORCID ; Kralicek, Andrew; Mingorance, Jesús CSIC ORCID; Palacios, Juan Manuel; Vicente, Miguel CSIC ORCID; Andreu, José Manuel CSIC ORCID artículo
5closedAccessaccesoRestringido.pdf.jpg26-ago-2016Aggregated compound biological signatures facilitate phenotypic drug discovery and target elucidationCortés Cabrera, Álvaro CSIC ORCID; Lucena-Agell, Daniel CSIC ORCID ; Redondo-Horcajo, Mariano CSIC ORCID ; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Fasching, Bernhard; Petrone, Paula M.artículo
6openAccessacsomega_oliva_2023.pdf.jpg13-ene-2023Alternative approaches to understand microtubule cap morphology and functionOliva, María A. CSIC ORCID ; Gago, Federico CSIC ORCID; Kamimura, Shinji; Díaz, José Fernando CSIC ORCID artículo
7openAccessOncotarget.pdf.jpg20-may-2016Antivascular and antitumor properties of the tubulin-binding chalcone TUB091Canela, María-Dolores CSIC; Noppen, Sam; Bueno, Oskia CSIC; Prota, Andrea E.; Bargsten, Katja; Sáez-Calvo, Gonzalo CSIC; Jimeno, M. Luisa CSIC ORCID; Benkhei, Mohammed; Ribatti, Domenico; Velázquez, Sonsoles CSIC ORCID CVN; Camarasa Rius, María José CSIC ORCID; Díaz, José Fernando CSIC ORCID ; Steinmetz, Michel O.; Priego, Eva María CSIC ORCID; Peréz-Pérez, María-Jesús CSIC ORCID ; Liekens, Sandraartículo
8closedAccessrestringido.pdf.jpgjul-2008Apo-Hsp90 coexists in two open conformational states in solutionBron, P.; Giudice, E.; Rolland, J.P.; Martínez Buey, Rubén CSIC ORCID; Barbier, Pascale; Díaz, José Fernando CSIC ORCID ; Peyrot, Vincent; Thomas, D.; Garnier, Cyrilleartículo
9closedAccess2007Arylthioindole inhibitors of tubulin polymerization. 3. Biological evaluation, structure-activity relationships and molecular modeling studiesLa Regina, Giuseppe; Edler, Michael C.; Brancale, Andrea; Kandil, Sahar; Coluccia, Antonio; Piscitelli, Francesco; Hamel, Ernest; De Martino, Gabriella; Matesanz, Ruth CSIC ; Díaz, José Fernando CSIC ORCID ; Scovassi, Anna Ivana; Prosperi, Ennio; Lavecchia, Antonio; Novellino, Ettore; Artico, Marino; Silvestri, Romanoartículo
10closedAccessaccesoRestringido.pdf.jpg15-mar-2018Au@p4VP core@shell pH-sensitive nanocomposites suitable for drug entrapmentClara-Rahola, Joaquim; Moscoso, Ana; Ruiz-Muelle, Ana Belén; Laurenti, Marco; Formanek, Petr; Lopez-Romero, Juan M.; Fernández, Ignacio CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Rubio-Retama, Jorge; Fery, A.; Contreras-Cáceres, Rafaelartículo
11closedAccess2007Characterizing Ligand-Microtubule binding by competition methodsDíaz, José Fernando CSIC ORCID ; Martínez Buey, Rubén CSIC ORCIDartículo
12openAccessStructure_Estévez-Gallego_2022.pdf.jpg5-ene-2023Chemical modulation of microtubule structure through the laulimalide/peloruside siteEstévez-Gallego, Juan CSIC ORCID ; Álvarez-Bernad, Beatriz CSIC; Benet, Pera; Wullschleger, Christoph; Raes, Olivier; Menche, Dirk; Martínez, Juan Carlos; Lucena-Agell, Daniel CSIC ORCID ; Prota, Andrea E.; Bonato, Francesca CSIC ORCID; Bargsten, Katja; Cornelus, Jelle; Giménez-Abián, Juan F. CSIC ; Northcote, Peter; Steinmetz, Michel O.; Kamimura, Shinji; Altmann, Karl-Heinz; Paterson, Ian; Gago, Federico CSIC ORCID; Van der Eycken, Johan; Díaz, José Fernando CSIC ORCID ; Oliva, María A. CSIC ORCID artículo
13openAccessDevelopemental Cell_2021_ Thakkar paper.pdf.jpg6-dic-2021CLIP-170S is a microtubule +TIP variant that confers resistance to taxanes by impairing drug-target engagementThakkar, Prashant V.; Kita, Katsuhiro; Del Castillo, Urko; Galletti, Giuseppe; Madhukar, Neel; Vila Navarro, Elena; Barasoain, Isabel CSIC ; Goodson, Holly V.; Sackett, Dan L.; Díaz, José Fernando CSIC ORCID ; Lu, Yao CSIC ORCID; RoyChoudhary, Arindam; Molina, Henrik; Elemento, Olivier; Shah, Manish A.; Giannakakou, Paraskeviartículo
14closedAccessaccesoRestringido.pdf.jpg2012Comparative Binding Energy (COMBINE) Analysis Supports a Proposal for the Binding Mode of Epothilones to β-TubulinCoderch, Claire; Klett, Javier CSIC ORCID; Morreale, Antonio; Díaz, José Fernando CSIC ORCID ; Gago, Federico CSIC ORCIDartículo
15openAccessaccesoRestringido.pdf.jpg2018Conformational mimetics of the α-methyl chalcone TUB091 binding tubulin: Design, synthesis and antiproliferative activityBueno, Oskia CSIC; Tobajas, Gloria; Quesada, Ernesto CSIC ORCID ; Estévez-Gallego, Juan CSIC ORCID ; Noppen, Sam; Camarasa Rius, María José CSIC ORCID; Díaz, José Fernando CSIC ORCID ; Liekens, Sandra; Priego, Eva María CSIC ORCID; Peréz-Pérez, María-Jesús CSIC ORCID artículo
16openAccessJ. Biol. Chem.-2010-Bustamante-33184-96.pdf.jpg22-oct-2010Cpl-7, a Lysozyme Encoded by a Pneumococcal Bacteriophage with a Novel Cell Wall-Binding MotifBustamante, Noemí CSIC; Campillo, Nuria E. CSIC ORCID ; García, Ernesto CSIC ORCID ; Gallego-Páramo, Cristina CSIC; Pera, Benet CSIC; Diakun, Gregory P.; Sáiz, José Luis CSIC; García, Pedro CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Menéndez, Margarita CSIC ORCIDartículo
17openAccessijms-20-01392.pdf.jpg20-mar-2019Crystal Structure of the Cyclostreptin-Tubulin Adduct: Implications for Tubulin Activation by Taxane-Site LigandsBalaguer, Francisco de Asís CSIC ORCID; Mühlethaler, Tobias; Estévez-Gallego, Juan CSIC ORCID ; Calvo, Enrique; Giménez-Abián, Juan F. CSIC ; Risinger, April L.; Sorensen, Erik J.; Vanderwal, Christopher D.; Altmann, Karl-Heinz; Mooberry, Susan; Steinmetz, Michel O.; Oliva, María A. CSIC ORCID ; Prota, Andrea E.; Díaz, José Fernando CSIC ORCID artículo
18closedAccessaccesoRestringido.pdf.jpg30-ago-2005Cyclostreptin (FR182877), an Antitumour Tubulin-Polymerizing Agent Deficient in Enhancing Tubulin Assembly Despite Its High Affinity for the Taxoid SiteEdler, Michael C.; Martínez Buey, Rubén CSIC ORCID; Gussio, Rick; Marcus, Adam I.; Vanderwal, Christopher D.; Sorensen, Erik J.; Díaz, José Fernando CSIC ORCID ; Giannakakou, Paraskevi; Hamel, Ernestartículo
19openAccesscyclostreptin_Buey.pdf.jpgene-2007Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sitesMartínez Buey, Rubén CSIC ORCID; Calvo, Enrique; Barasoain, Isabel CSIC ; Pineda, Oriol; Edler, Michael C.; Matesanz, Ruth CSIC ; Cerezo, Gemma; Vanderwal, Christopher D.; Day, Billy W.; Sorensen, Erik J.; López, Juan Antonio; Andreu, José Manuel CSIC ORCID ; Hamel, Ernest; Díaz, José Fernando CSIC ORCID artículo
20closedAccessrestringido.pdf.jpgene-2012Cyclostreptin Derivatives Specifically Target Cellular Tubulin and Further Map the Paclitaxel SiteCalvo, Enrique; Barasoain, Isabel CSIC ; Matesanz, Ruth CSIC ; Pera, Benet CSIC; Camafeita, Emilio; Pineda, Oriol; Hamel, Ernest; Vanderwal, Christopher D.; Andreu, José Manuel CSIC ORCID ; López, Juan Antonio; Díaz, José Fernando CSIC ORCID artículo