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Clapés Saborit, Pere

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Perfil

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Firma en Digital.CSIC (*)
Clapés Saborit, Pere
 
Centro o Instituto
CSIC - Instituto de Quimica Avanzada de Cataluña (IQAC)
 
Especialización
Chemist specialized in biocatalysis and biotransformation in organic asymmetric synthesis of bioactive molecules. He’s published over 100 scientific papers and patents in the field of biocatalysis. He is currently head of the Biotransformation and Bioactive Molecules Group were he conducts research on the exploitation of biocatalysts in asymmetric carbon-carbon bond formation as a means to rapidly create chiral structures of high complexity to produce novel compounds for bioactivity testing. The research in close cooperation with the other participants of the group includes cascade chemoenzymatic synthesis, analysis, purification, computational models, and biological evaluation of products. Prof. Dr. Clapés product research is focused on cancer, particularly in metastasis, and the prevention of the metabolic syndrome, with particular focus on the control of blood sugar.
 
Email
pere.clapes@iqac.csic.es
 
ORCID
 
WoS ResearcherID - Publons
 
Scopus AuthorID
 
Página web
 
Otros - ResearchGate
 

Publications

Results 1-20 of 84 (Search time: 0.033 seconds).

RightsPreviewIssue DateTitleAuthor(s)Type
1openAccess2-Keto-3-Deoxy-L-Rhamnonate Aldolase (YfaU) as Catalyst in.pdf.jpg11-May-20172-Keto-3-Deoxy-L-Rhamnonate Aldolase (YfaU) as Catalyst in Aldol Additions of Pyruvate to Amino Aldehyde DerivativesHernández Sánchez, Karel CSIC; Gómez, Ariadna; Joglar Tamargo, Jesús CSIC ORCID; Bujons, Jordi; Parella, Teodor; Clapés Saborit, Pere CSIC ORCID artículo
2openAccess25-Jul-2021A cascade reaction for the synthesis of d-fagomine precursor revisited: Kinetic insight and understanding of the systemSudar, Martina; Česnik, Morana; Clapés Saborit, Pere CSIC ORCID ; Pohl, Martina; Vasić-Rački, Đurđa; Findrik Blažević, Zvjezdanaartículo
3closedAccessAcceso_restringido.pdf.jpg1988A comparative study of the performance of solid supported and soluble αchymotrypsin for the enzymatic synthesis of kyotorphinClapés Saborit, Pere CSIC ORCID ; Valencia Parera, Gregorio; Reig Isart, Francisca CSIC ; García-Antón, José María; Mata-Álvarez, Joanartículo
4closedAccess2010A Mutant D-Fructose-6-Phosphate Aldolase (Ala129Ser) with Improved Affinity towards Dihydroxyacetone for the Synthesis of Polyhydroxylated CompoundsCastillo Expósito, José Antonio; Guérard-Hélaine, Christine; Gutiérrez, Mariana CSIC; Garrabou, Xavier CSIC ORCID; Sancelme, Martine; Schürmann, Melanie; Inoue, Tomoyuki; Hélaine, Virgil; Charmantray, Franck; Gefflaut, Thierry; Hecquet, Laurence; Joglar Tamargo, Jesús CSIC ORCID; Clapés Saborit, Pere CSIC ORCID ; Sprenger, Georg A.; Lemaire, Marielleartículo
5openAccessc5ra14414k.pdf.jpg2015A new concept for production of (3S,4R)-6-[(benzyloxycarbonyl)amino]-5,6-dideoxyhex-2-ulose, a precursor of d-fagomineSudar, M.; Findrik Blažević, Zvjezdana; Vasić -Rački, D.; Soler, Anna; Clapés Saborit, Pere CSIC ORCID artículo
6closedAccess24-Jan-2005Aldol additions of dihydroxyacetone phosphate to N-Cbz-amino aldehydes catalyzed by L-fuculose-1-phosphate aldolase in emulsion systems: inversion of stereoselectivity as a function of the acceptor aldehydeEspelt, Laia; Bujons Vilàs, Jordi; Parella, Teodor; Calveras Ibáñez, Jordi; Joglar Tamargo, Jesús CSIC ORCID; Delgado Cirilo, Antonio; Clapés Saborit, Pere CSIC ORCID artículo
7openAccessAldolase-Catalyzed Asymmetric Synthesis of N-Heterocycles by Addition of Simple Aliphatic Nucleophiles to Aminoaldehydes.pdf.jpg28-Jan-2019Aldolase-Catalyzed Asymmetric Synthesis of N-Heterocycles by Addition of Simple Aliphatic Nucleophiles to AminoaldehydesRoldán, Raquel; Hernández Sánchez, Karel CSIC; Joglar Tamargo, Jesús CSIC ORCID; Bujons, Jordi; Parella, Teodor; Fessner, Wolf Dieter; Clapés Saborit, Pere CSIC ORCID artículo
8closedAccessaccesoRestringido.pdf.jpg2014Aldolase-catalyzed synthesis of conformationally constrained iminocyclitols: Preparation of polyhydroxylated benzopyrrolizidines and cyclohexapyrrolizidinesLaborda, Pedro CSIC ORCID; Sayago, Francisco J. CSIC ORCID; Cativiela, Carlos CSIC ORCID; Parella, Teodor; Joglar Tamargo, Jesús CSIC ORCID; Clapés Saborit, Pere CSIC ORCID artículo
9closedAccessAcceso_restringido.pdf.jpgJun-2004Amino acid-based surfactantsInfante, María Rosa CSIC ; Pérez, Lourdes CSIC ORCID ; Pinazo Gassol, Aurora; Clapés Saborit, Pere CSIC ORCID ; Morán, María del Carmen; Angelet, Marta; García, María Teresa; Vinardell, M. Pilar CSIC ORCIDartículo
10closedAccessAcceso_restringido.pdf.jpg2002Amino acid-based surfactants: Enzymatic synthesis, properties and potential applicationsClapés Saborit, Pere CSIC ORCID ; Infante, María Rosa CSIC artículo de revisión
11openAccess1-s2.0-S0009250920308447-main.pdf.jpg15-Feb-2021An innovative route for the production of atorvastatin side-chain precursor by DERA-catalysed double aldol additionŠvarc, Anera; Fekete, Melinda; Hernández, Karel; Clapés Saborit, Pere CSIC ORCID ; Findrik Blažević, Zvjezdana; Szekrenyi, Anna CSIC; Skendrović, Dino; Vasić-Rački, Đurđa; Charnock, Simon J.; Presečki, Ana Vrsalovićartículo
12closedAccessAcceso_restringido.pdf.jpgOct-1989Application of a recycle reactor to obtain kinetic data from progress curves immobilized-enzyme catalyzed reactionsClapés Saborit, Pere CSIC ORCID ; Mata-Álvarez, Joan; García-Antón, José María; Reig Isart, Francisca CSIC ; Valencia Parera, Gregorioartículo
13closedAccess2-Mar-2004Assessment of primary eye and skin irritants by in vitro cytotoxicity and phototoxicity models: an in vitro approach of new arginine-based surfactant-induced irritationBenavides, Tomás; Mitjans, Montserrat; Martínez, Verónica; Clapés Saborit, Pere CSIC ORCID ; Infante, María Rosa CSIC ; Clothier, Richard; Vinardell, M. Pilar CSIC ORCIDartículo
14closedAccess21-May-2004Assessment of the potential irritation and photoirritation of novel amino acid-based surfactants by in vitro methods as alternative to the animal testsBenavides, Tomás; Martínez, Verónica; Mitjans, Montserrat; Infante, María Rosa CSIC ; Morán, María del Carmen; Clapés Saborit, Pere CSIC ORCID ; Clothier, Richard; Vinardell, M. Pilar CSIC ORCIDartículo
15openAccessBiocatalytic Aldol Addition of Simple Aliphatic Nucleophiles to.pdf.jpg8-Aug-2018Biocatalytic Aldol Addition of Simple Aliphatic Nucleophiles to HydroxyaldehydesRoldán, Raquel; Hernández Sánchez, Karel CSIC; Joglar Tamargo, Jesús CSIC ORCID; Bujons, Jordi; Parella, Teodor; Sánchez-Moreno, Israel CSIC ; Hélaine, Virgil; Lemaire, Marielle; Guérard-Hélaine, Christine; Fessner, Wolf Dieter; Clapés Saborit, Pere CSIC ORCID artículo
16openAccessBiocatalytic construction JACS.pdf.jpg4-Nov-2020Biocatalytic Construction of Quaternary Centers by Aldol Addition of 3,3-Disubstituted 2-Oxoacid Derivatives to AldehydesMarín-Valls, Roser; Hernández Sánchez, Karel CSIC; Bolte, Michael; Parella, Teodor; Joglar Tamargo, Jesús CSIC ORCID; Bujons Vilàs, Jordi; Clapés Saborit, Pere CSIC ORCID artículo
17openAccessacscatal.3c00367.pdf.jpg1-Jan-2023Biocatalytic Synthesis of Homochiral 2-Hydroxy-4-butyrolactone Derivatives by Tandem Aldol Addition and Carbonyl ReductionMoreno, Carlos J.; Hernández, Karel; Gittings, Samantha; Bolte, Michael; Joglar, Jesús; Bujons, Jordi; Parella, Teodor; Clapés Saborit, Pere CSIC ORCID artículo
18openAccessAdv Synth Catal - 2023 - Pickl - Biocatalytic Transamination of Aldolase‐Derived 3‐Hydroxy Ketones.pdf.jpg1-Jan-2023Biocatalytic Transamination of Aldolase-Derived 3-Hydroxy KetonesPickl, Mathias; Ebner, Markus; Gittings, Samantha; Clapés Saborit, Pere CSIC ORCID ; Kroutil, Wolfgangartículo
19closedAccessBreaking the dogma of aldolase specificitypostprint.pdf.jpg11-Apr-2017Breaking the Dogma of Aldolase Specificity: Simple Aliphatic Ketones and Aldehydes are Nucleophiles for Fructose-6-phosphate AldolaseRoldán, Raquel; Sánchez-Moreno, Israel CSIC ; Scheidt, Thomas; Hélaine, Virgil; Lemaire, Marielle; Parella, T.; Clapés Saborit, Pere CSIC ORCID ; Fessner, Wolf Dieter; Guérard-Hélaine, Christineartículo
20openAccessCascade enzymatic synthesis of L -homoserine – mathematical modelling as a tool for process optimisation and design.pdf.jpg27-Jan-2020Cascade enzymatic synthesis of L -homoserine – mathematical modelling as a tool for process optimisation and designČesnik, Morana; Sudar, M.; Hernández, Karel; Charnock, Simon J.; Vasić-Rački, Đ.; Clapés Saborit, Pere CSIC ORCID ; Findrik Blažević, Zvjezdanaartículo