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Firma en Digital.CSIC (*):
Clapés Saborit, Pere
 
Centro o Instituto:
CSIC - Instituto de Quimica Avanzada de Cataluña (IQAC)
 
Especialización:
Chemist specialized in biocatalysis and biotransformation in organic asymmetric synthesis of bioactive molecules. He’s published over 100 scientific papers and patents in the field of biocatalysis. He is currently head of the Biotransformation and Bioactive Molecules Group were he conducts research on the exploitation of biocatalysts in asymmetric carbon-carbon bond formation as a means to rapidly create chiral structures of high complexity to produce novel compounds for bioactivity testing. The research in close cooperation with the other participants of the group includes cascade chemoenzymatic synthesis, analysis, purification, computational models, and biological evaluation of products. Prof. Dr. Clapés product research is focused on cancer, particularly in metastasis, and the prevention of the metabolic syndrome, with particular focus on the control of blood sugar.
 
Email:
pere.clapes@iqac.csic.es
 
 
WoS ResearcherID - Publons:
 
Scopus AuthorID:
 
Página web:
 
Otros - ResearchGate:
 

Results 1-20 of 52 (Search time: 0.001 seconds).

RightsPreviewIssue DateTitleAuthor(s)Type
1openAccess2-Keto-3-Deoxy-L-Rhamnonate Aldolase (YfaU) as Catalyst in.pdf.jpg11-May-20172-Keto-3-Deoxy-L-Rhamnonate Aldolase (YfaU) as Catalyst in Aldol Additions of Pyruvate to Amino Aldehyde DerivativesHernández Sánchez, Karel ; Gómez, Ariadna; Joglar Tamargo, Jesús ; Bujons, Jordi; Parella, Teodor; Clapés Saborit, Pere  artículo
2closedAccess2010A Mutant D-Fructose-6-Phosphate Aldolase (Ala129Ser) with Improved Affinity towards Dihydroxyacetone for the Synthesis of Polyhydroxylated CompoundsCastillo Expósito, José A.; Guérard-Hélaine, Christine; Gutiérrez, Mariana ; Garrabou, Xavier ; Sancelme, Martine; Schürmann, Melanie; Inoue, Tomoyuki; Hélaine, Virgil; Charmantray, Franck; Gefflaut, Thierry; Hecquet, Laurence; Joglar Tamargo, Jesús ; Clapés Saborit, Pere  ; Sprenger, Georg A.; Lemaire, Marielleartículo
3openAccessc5ra14414k.pdf.jpg2015A new concept for production of (3S,4R)-6-[(benzyloxycarbonyl)amino]-5,6-dideoxyhex-2-ulose, a precursor of d-fagomineSudar, M.; Findrik, Z.; Vasić -Rački, D.; Soler, Anna; Clapés Saborit, Pere  artículo
4closedAccess24-Jan-2005Aldol additions of dihydroxyacetone phosphate to N-Cbz-amino aldehydes catalyzed by L-fuculose-1-phosphate aldolase in emulsion systems: inversion of stereoselectivity as a function of the acceptor aldehydeEspelt, Laia; Bujons Vilàs, Jordi ; Parella, Teodor; Calveras Ibáñez, Jordi; Joglar Tamargo, Jesús ; Delgado Cirilo, Antonio ; Clapés Saborit, Pere  artículo
5openAccessAldolase-Catalyzed Asymmetric Synthesis of N-Heterocycles by Addition of Simple Aliphatic Nucleophiles to Aminoaldehydes.pdf.jpg28-Jan-2019Aldolase-Catalyzed Asymmetric Synthesis of N-Heterocycles by Addition of Simple Aliphatic Nucleophiles to AminoaldehydesRoldán, Raquel; Hernández Sánchez, Karel ; Joglar Tamargo, Jesús ; Bujons, Jordi; Parella, Teodor; Fessner, Wolf Dieter; Clapés Saborit, Pere  artículo
6closedAccessaccesoRestringido.pdf.jpg2014Aldolase-catalyzed synthesis of conformationally constrained iminocyclitols: Preparation of polyhydroxylated benzopyrrolizidines and cyclohexapyrrolizidinesLaborda, Pedro ; Sayago, Francisco J. ; Cativiela, Carlos ; Parella, Teodor; Joglar Tamargo, Jesús ; Clapés Saborit, Pere  artículo
7closedAccess2-Mar-2004Assessment of primary eye and skin irritants by in vitro cytotoxicity and phototoxicity models: an in vitro approach of new arginine-based surfactant-induced irritationBenavides, Tomás; Mitjans, Montserrat; Martínez, Verónica; Clapés Saborit, Pere  ; Infante, María Rosa ; Clothier, Richard; Vinardell, M. Pilar artículo
8closedAccess21-May-2004Assessment of the potential irritation and photoirritation of novel amino acid-based surfactants by in vitro methods as alternative to the animal testsBenavides, Tomás; Martínez, Verónica; Mitjans, Montserrat; Infante, María Rosa ; Morán, María del Carmen; Clapés Saborit, Pere  ; Clothier, Richard; Vinardell, M. Pilar artículo
9openAccessBiocatalytic Aldol Addition of Simple Aliphatic Nucleophiles to.pdf.jpg8-Aug-2018Biocatalytic Aldol Addition of Simple Aliphatic Nucleophiles to HydroxyaldehydesRoldán, Raquel; Hernández Sánchez, Karel ; Joglar Tamargo, Jesús ; Bujons, Jordi; Parella, Teodor; Sánchez-Moreno, Israel ; Hélaine, Virgil; Lemaire, Marielle; Guérard-Hélaine, Christine; Fessner, Wolf Dieter; Clapés Saborit, Pere  artículo
10embargoedAccessja0c09994_si_002.pdf.jpg4-Nov-2020Biocatalytic Construction of Quaternary Centers by Aldol Addition of 3,3-Disubstituted 2-Oxoacid Derivatives to AldehydesMarín-Valls, Roser; Hernández Sánchez, Karel ; Bolte, Michael; Parella, Teodor; Joglar Tamargo, Jesús ; Bujons Vilàs, Jordi ; Clapés Saborit, Pere  artículo
11closedAccessBreaking the dogma of aldolase specificitypostprint.pdf.jpg11-Apr-2017Breaking the Dogma of Aldolase Specificity: Simple Aliphatic Ketones and Aldehydes are Nucleophiles for Fructose-6-phosphate AldolaseRoldán, Raquel; Sánchez-Moreno, Israel ; Scheidt, Thomas; Hélaine, Virgil; Lemaire, Marielle; Parella, T.; Clapés Saborit, Pere  ; Fessner, Wolf Dieter; Guérard-Hélaine, Christineartículo
12openAccessCascade enzymatic synthesis of L -homoserine – mathematical modelling as a tool for process optimisation and design.pdf.jpg27-Jan-2020Cascade enzymatic synthesis of L -homoserine – mathematical modelling as a tool for process optimisation and designČesnik, M.; Sudar, M.; Hernández, Karel; Charnock, S.; Vasić-Rački, Đ.; Clapés Saborit, Pere  ; Findrik Blažević, Z.artículo
13openAccesscs9b01646_si_001.pdf.jpg8-Jul-2019Chemoenzymatic Hydroxymethylation of Carboxylic Acids by Tandem Stereodivergent Biocatalytic Aldol Reaction and Chemical DecarboxylationMarín-Valls, Roser; Hernández Sánchez, Karel ; Bolte, Michael; Joglar Tamargo, Jesús ; Bujons, Jordi; Clapés Saborit, Pere  artículo
14openAccessadsc202100145-sup-0001-misc_information.pdf.jpg22-Mar-2021Chemoenzymatic Production of Enantiocomplementary 2‐Substituted 3‐Hydroxycarboxylic Acids from l‐α‐Amino AcidsPickl, Mathias; Marín‐Valls, Roser; Joglar, Jesús; Bujons, Jordi; Clapés Saborit, Pere  artículo
15closedAccess14-Sep-2006Chemoenzymatic Synthesis and Antimicrobial and Haemolytic Activities of Amphiphilic Bis(phenylacetylarginine) DerivativesCastillo Expósito, José A.; Infante, María Rosa ; Manresa, Ángeles; Vinardell, M. Pilar ; Mitjans, Montserrat; Clapés Saborit, Pere  artículo
16closedAccess17-Jul-2007Chemoenzymatic Synthesis and Inhibitory Activities of Hyacinthacines A1 and A2 Stereoisomers.Calveras Ibáñez, Jordi; Casas, Josefina  ; Parella, Teodor; Joglar Tamargo, Jesús ; Clapés Saborit, Pere  artículo
17openAccessACS_catalysis_2017_1707.pdf.jpgFeb-2017Combining aldolases and transaminases for the synthesis of 2‑amino-4-hydroxybutanoic acidHernández Sánchez, Karel ; Bujons, Jordi; Joglar Tamargo, Jesús ; Charnock, Simon J.; Domínguez de María, Pablo; Fessner, Wolf Dieter; Clapés Saborit, Pere  artículo
18closedAccess30-Jun-2006Comparative behaviour of proteinases from the latex of Carica papaya and Funastrum clausum as catalysts for the synthesis of Z-Ala-Phe-OMeMorcelle, Susana R.; Barberis, Sonia; Priolo, Nora; Caffini, Néstor O.; Clapés Saborit, Pere  artículo
19openAccessCastillo_Jose_et_al.pdf.jpg8-Feb-2006Comparative study of the antimicrobial activity of bis(Nα-caproyl-L-arginine)-1,3- propanediamine dihydrochloride and chlorhexidine dihydrochloride against Staphylococcus aureus and Escherichia coliCastillo Expósito, José A.; Clapés Saborit, Pere  ; Infante, María Rosa ; Comas, Jaume; Manresa, Ángelesartículo
20openAccessComplete switch of reaction specificity of an aldolase by directed.pdf.jpg8-Jun-2018Complete switch of reaction specificity of an aldolase by directed evolution in vitro: Synthesis of generic aliphatic aldol productsJunker, Sebastian; Roldán, Raquel; Joosten, Henk-Jan; Clapés Saborit, Pere  ; Fessner, Wolf-Dieterartículo