1. DIGITAL.CSIC

Sainz, Bruno Jr.

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Perfil

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Firma en Digital.CSIC (*)
Sainz, Bruno Jr.
 
Centro o Instituto
CSIC-UAM - Instituto de Investigaciones Biomédicas Alberto Sols (IIBM)
 
Departamento
Biología del Cáncer. Grupo: Células Madre de Cáncer y Microambiente Tumoral.
 
Categoría Profesional
Investigador Contratado
 
Especialización
Estudio de las CSCs en el contexto del adenocarcinoma ductal de páncreas (PDAC).
 
Email
b.sainz@iibm.uam.es
 
ORCID
 
Perfil en Google Scholar
 
WoS ResearcherID - Publons
 
Scopus AuthorID
 
Página web
 
Otros - ResearchGate
 
Otros identificadores (con url)
 

Publications

Results 1-20 of 42 (Search time: 0.043 seconds).

RightsPreviewIssue DateTitleAuthor(s)Type
1openAccessDec-2017A current perspective on cancer immune therapy: step-by-step approach to constructing the magic bulletD’Errico, Gabriele; Machado, Heather L.; Sainz, Bruno Jr. artículo de revisión
2openAccessBCL3_couples_cancer_AI_Preprint_Art2021.pdf.jpgJul-2021Bcl3 Couples Cancer Stem Cell Enrichment With Pancreatic Cancer Molecular SubtypesAi, Jiaoyu; Wörmann, Sonja M.; Görgülü, Kivanc; Vallespinós, Mireia CSIC; Zagorac, Sladjana; Alcalá, Sonia CSIC ORCID; Wu, Nan; Kabacaoglu, Derya; Berninger, Alexandra; Navarro, Diego CSIC; Kaya-Aksoy, Ezgi; Ruess, Dietrich A.; Ciecielski, Katrin J.; Kowalska, Marlena; Demir, Ihsan Ekin; Ceyhan, Güralp O.; Heid, Irina; Braren, Rickmer; Riemann, Marc; Schreiner, Sabrina; Hofmann, Samuel; Kutschke, Maria; Jastroch, Martin; Slotta-Huspenina, Julia; Muckenhuber, Alexander; Schlitter, Anna Melissa; Schmid, Roland M.; Steiger, Katja; Diakopoulos, Kalliope N.; Lesina, Marina; Sainz, Bruno Jr. ; Algül, Hanaartículo
3openAccessBiomarkers_Associated_with_Regorafenib_Conde_PV_Art2021.pdf.jpg2021Biomarkers Associated with Regorafenib First-Line Treatment Benefits in Metastatic Colorectal Cancer Patients: REFRAME Molecular StudyConde, Elisa; Earl, Julie; Crespo-Toro, Lorena; Blanco-Agudo, Carolina; Ramos-Muñoz, Edurne; Rodríguez-Serrano, Macarena; Martínez Ávila, Jose Carlos; Salinas-Muñoz, Laura; Serrano-Huertas, Silvia; Ferreiro, Reyes; Rodríguez-Garrote, Mercedes; Sainz, Bruno Jr. ; Massutí, Bartomeu; García Alfonso, Pilar; Benavides, Manuel; Aranda, Enrique; García-Bermejo, María Laura; Carrato, Alfredoartículo
4openAccesscanstemcell.pdf.jpg2016Cancer stem cells and macrophages: implications in tumor biology and therapeutic strategiesSainz, Bruno Jr. ; Carron, Emily; Vallespinós, Mireia CSIC; Machado, Heather L.artículo
5closedAccessaccesoRestringido.pdf.jpgNov-2016Current evidence for cancer stem cells in gastrointestinal tumors and future research perspectivesLópez-Gómez, Miriam; Casado, Enrique CSIC; Muñoz, Marta; Alcalá, Sonia CSIC ORCID; Moreno-Rubio, Juan; D’Errico, Gabriele; Jiménez-Gordo, Ana María; Salinas, Silvia; Sainz, Bruno Jr. artículo de revisión
6openAccessCROH17ReviSUB.pdf.jpg2018Current perspectives on the crosstalk between lung cancer stem cells and cancer-associated fibroblastsAlguacil-Núñez, Cristina; Ferrer-Ortiz, Inés; García-Verdú, Elena; López-Pirez, Pilar; Llorente-Cortijo, Irene Maria; Sainz, Bruno Jr. artículo
7openAccess92Cluster.pdf.jpg2016DNMT1 inhibition reprograms pancreatic cancer stem cells via upregulation of the miR-17-92 clusterZagorac, Sladjana; Alcalá, Sonia CSIC ORCID; Fraga, Mario F. CSIC ORCID; Heeschen, Christopher; Sainz, Bruno Jr. artículo
8openAccessDysregulated_splicing_factor_SF3B1_Alors_PV_Art2021.pdf.jpg2021Dysregulated splicing factor SF3B1 unveils a dual therapeutic vulnerability to target pancreatic cancer cells and cancer stem cells with an anti-splicing drugAlors-Perez, Emilia; Blázquez-Encinas, Ricardo; Alcalá, Sonia CSIC ORCID; Viyuela-García, Cristina; Pedraza-Arévalo, Sergio; Herrero-Aguayo, Vicente; Jiménez-Vacas, Juan M.; Mafficini, Andrea; Sánchez-Frías, Marina E.; Cano, María T.; Abollo-Jiménez, Fernando CSIC; Marín-Sanz, Juan A.; Cabezas-Sainz, Pablo; Lawlor, Rita T.; Luchini, Claudio; Sánchez, Laura; Sánchez-Hidalgo, Juan M.; Ventura, Sebastián; Martin-Hijano, Laura; Gahete, Manuel D.; Scarpa, Aldo; Arjona-Sánchez, Álvaro; Ibáñez-Costa, Alejandro; Sainz, Bruno Jr. ; Luque, Raúl M.; Castaño, Justo P.artículo
9openAccessEMTcells.pdf.jpg2019EMT and stemness—key players in pancreatic cancer stem cellsRodriguez-Aznar, Eva; Wiesmüller, Lisa; Sainz, Bruno Jr. ; Hermann, Patrick C.artículo
10openAccessExploiting _Valle_PV_Ar2020.pdf.jpg2020Exploiting oxidative phosphorylation to promote the stem and immunoevasive properties of pancreatic cancer stem cellsValle, Sandra; Alcalá, Sonia CSIC ORCID; Martin-Hijano, Laura; Cabezas-Sainz, Pablo; Navarro, Diego CSIC; Ramos, Edurne; Yuste Pérez, Lourdes CSIC; Tiwary, Kanishka; Walter, Karolin; Ruiz-Cañas, Laura CSIC; Alonso-Nocelo, Marta; Rubiolo, Juan A.; González-Arnay, Emilio; Heeschen, Christopher; García-Bermejo, María Laura; Hermann, Patrick C.; Sánchez, Laura; Sancho, Patricia CSIC ORCID; Fernández-Moreno, Miguel Ángel CSIC ORCID; Sainz, Bruno Jr. artículo
11openAccessExtensive preclinical validation of combined_Frank_PV_Art2022.pdf.jpg15-Nov-2022Extensive preclinical validation of combined RMC-4550 and LY3214996 supports clinical investigation for KRAS mutant pancreatic cancerFrank, Katrin J.; Mulero-Sánchez, Antonio; Berninger, Alexandra; Ruiz-Cañas, Laura CSIC; Bosma, Astrid; Görgülü, Kivanc; Wu, Nan; Diakopoulos, Kalliope N.; Kaya-Aksoy, Ezgi; Ruess, Dietrich A.; Kabacaoglu, Derya; Schmidt, Fränze; Kohlmann, Larissa; Tellingen, Olaf van; Thijssen, Bram; Van de Ven, Marieke; Proost, Natalie; Kossatz, Susanne; Weber, Wolfgang A.; Sainz, Bruno Jr. ; Bernards, Rene; Algül, Hana; Lesina, Marina; Mainardi, Saraartículo
12openAccessGlutathione_Jagust_PV_Art2020.pdf.jpg26-Nov-2020Glutathione metabolism is essential for self-renewal and chemoresistance of pancreatic cancer stem cellsJagust, Petra; Alcalá, Sonia CSIC ORCID; Sainz, Bruno Jr. ; Heeschen, Christopher; Sancho, Patricia CSIC ORCIDartículo
13openAccessacinar-ductal.pdf.jpg2017Human pluripotent stem cell-derived acinar/ductal organoids generate human pancreas upon orthotopic transplantation and allow disease modellingHohwieler, Meike; Illing, Anett; Hermann, Patrick C.; Mayer, Tobias; Stockmann, Marianne; Perkhofer, Lukas; Eiseler, Tim; Antony, Justin S.; Müller, Martin; Renz, Susanne; Kuo, Chao-Chung; Lin, Qiong; Sendler, Matthias; Breunig, Markus; Kleiderman, Susanne M.; Lechel, André; Zenker, Martin; Leichsenring, Michael; Rosendahl, Jonas; Zenke, Martin; Sainz, Bruno Jr. ; Mayerle, Julia; Costa, Ivan G.; Seufferlein, Thomas; Kormann, Michael; Wagner, Martin; Liebau, Stefan; Kleger, Alexanderartículo
14openAccessInduction_Cash_PV_Art2020.pdf.jpg4-Jul-2020Induction of Lysosome Membrane Permeabilization as a Therapeutic Strategy to Target Pancreatic Cancer Stem CellsCash, Timothy P.; Alcalá, Sonia CSIC ORCID; Rico-Ferreira, María del Rosario; Hernández Encinas, María Elena CSIC; García, Jennifer; Albarrán, María Isabel; Valle, Sandra; Muñoz, Javier CSIC ; Martínez-González, Sonia; Blanco-Aparicio, Carmen; Pastor, Joaquín; Serrano, Manuel; Sainz, Bruno Jr. artículo
15openAccessisgplasti.pdf.jpg2020ISG15 and ISGylation is required for pancreatic cancer stem cell mitophagy and metabolic plasticityAlcalá, Sonia CSIC ORCID; Sancho, Patricia CSIC ORCID; Martinelli, Paola; Navarro, Diego CSIC; Pedrero García, Coral; Martin-Hijano, Laura; Valle, Sandra; Earl, Julie; Rodríguez-Serrano, Macarena; Ruiz-Cañas, Laura CSIC; Rojas, Katerin; Carrato, Alfredo; García-Bermejo, María Laura; Fernández-Moreno, Miguel Ángel CSIC ORCID; Hermann, Patrick C.; Sainz, Bruno Jr. artículo
16openAccessLAMC2 marks_Delle_PV_Art2022.pdf.jpg2022LAMC2 marks a tumor-initiating cell population with an aggressive signature in pancreatic cancerDelle Cave, Donatella; Buonaiuto, Silvia; Sainz, Bruno Jr. ; Fantuz, Marco; Mangini, María; Carrer, Alessandro; Domenico, Annalisa Di; Lavazzo, Tea Teresa; Andolfi, Gennaro; Cortina, Carme; Sevillano, Marta; Heeschen, Christopher; Colonna, Vincenza; Corona, Marco; Cucciardi, Antonio; Guida, Martina Di; Batlle, Eduard; Luca, Annachiara De; Lonardo, Enzaartículo
17closedAccessaccesoRestringido.pdf.jpgJan-2019Levels of the Autophagy-Related 5 Protein Affect Progression and Metastasis of Pancreatic Tumors in MiceGörgülü, Kivanc; Diakopoulos, Kalliope N.; Ai, Jiaoyu; Schoeps, Benjamin; Kabacaoglu, Derya; Karpathaki, Angeliki F.; Ciecielski, Katrin J.; Kaya-Aksoy, Ezgi; Ruess, Dietrich A.; Berninger, Alexandra; Kowalska, Marlena; Stevanovic, Marija; Wörmann, Sonja M.; Wartmann, Thomas; Zhao, Yue; Halangk, Walter; Voronina, Svetlana; Tepikin, Alexey; Schlitter, Anna Melissa; Steiger, Katja; Artati, Anna; Adamski, Jerzy; Aichler, Michaela; Walch, Axel; Jastroch, Martin; Hartleben, Götz; Mantzoros, Christos S.; Weichert, Wilko; Schmid, Roland M.; Herzig, Stephan; Krüger, Achim; Sainz, Bruno Jr. ; Lesina, Marina; Algül, Hanaartículo
18openAccessMacrophages direct cancer_Alonso_PV_Art2022.pdf.jpg2022Macrophages direct cancer cells through a LOXL2-mediated metastatic cascade in pancreatic ductal adenocarcinomaAlonso-Nocelo, Marta; Ruiz-Cañas, Laura CSIC; Sancho, Patricia CSIC ORCID; Alcalá, Sonia CSIC ORCID; Pedrero García, Coral; Vallespinós, Mireia CSIC; López-Gil, Juan Carlos CSIC; Ochando, Marina; García-García, Elena; Trabulo, Sara María David; Martinelli, Paola; Sánchez-Tomero, Patricia; Sánchez-Palomo, Carmen; González-Santamaría, Patricia; Yuste Pérez, Lourdes CSIC; Wörmann, Sonja M.; Kabacaoglu, Derya; Earl, Julie; Martín, Alberto CSIC ORCID; Salvador, Fernando CSIC; Valle, Sandra; Martin-Hijano, Laura; Carrato, Alfredo; Erkan, Mert M.; García-Bermejo, María Laura; Hermann, Patrick C.; Algül, Hana; Moreno-Bueno, Gema CSIC ORCID; Heeschen, Christopher; Portillo, Francisco CSIC; Cano, Amparo CSIC; Sainz, Bruno Jr. artículo
19openAccessMEKvivo.pdf.jpg2019MEK inhibition targets cancer stem cells and impedes migration of pancreatic cancer cells in vitro and in vivoWalter, Karolin; Tiwary, Kanishka; Trajkovic-Arsic, Marija; Hidalgo-Sastre, Ana; Dierichs, Laura; Liffers, Sven T.; Gu, Jiangning; Gout, Johann; Schulte, Lucas-Alexander; Münch, Jan; Seufferlein, Thomas; Sainz, Bruno Jr. ; Siveke, Jens T.; Rodriguez-Aznar, Eva; Hermann, Patrick C.artículo
20openAccessmodelmicro.pdf.jpg2020Modeling cancer using zebrafish xenografts: Drawbacks for mimicking the human microenvironmentCabezas-Sainz, Pablo; Pensado-López, Alba; Sainz, Bruno Jr. ; Sánchez, Lauraartículo