1. DIGITAL.CSIC

Gavira Gallardo, J. A.

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Perfil

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Firma en Digital.CSIC (*)
Gavira Gallardo, J. A.
 
Centro o Instituto
CSIC - Instituto Andaluz de Ciencias de la Tierra (IACT)
 
Departamento
Laboratorio De Estudios Cristalográficos
 
Categoría Profesional
Científico Titular
 
Especialización
I graduated in Chemistry (Biochemistry) at the University of Granada (UGR) and obtained his PhD in protein crystallization in diffusion mass transport media working at the Spanish National Research Council (CSIC). My PhD thesis was awarded with the First Prize within the PhD Chemistry programme of the UGR. As Postdoctoral fellow I worked at the University of Huntsville (UAH) in Alabama (USA) and the Marshal Space Flight Centre (NASA) in protein crystallization methodologies and in situ resources utilization projects. In 2003, I joined the Laboratory of Crystallographic Studies (LEC) to lead the bio-crystallography research line, where I got a permanent position as Research Scientist of CSIC. My main research line focuses in the biotechnological applications of protein/enzyme crystals for drug formulations, as self-supported catalysts and as biosensors. I also maintain active collaborations with several groups in crystallographic studies to better understand structural biology of chemosensory pathway signalling proteins and enzyme fitness.
 
Email
jgavira@iact.ugr-csic.es
 
ORCID
 
Perfil en Google Scholar
 
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Scopus AuthorID
 
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Otros identificadores (con url)
 

Publications

Results 1-20 of 46 (Search time: 0.051 seconds).

RightsPreviewIssue DateTitleAuthor(s)Type
1closedAccessaccesoRestringido.pdf.jpg1-Jan-2019A novel cysteine carbamoyl-switch is responsible for the inhibition of formamidase, a nitrilase superfamily memberMartínez Rodríguez, Sergio; Conejero Muriel, Mayte CSIC ORCID; Gavira Gallardo, J. A. artículo
2openAccessIUCr.pdf.jpg19-Apr-2019A simple and versatile microfluidic device for efficient biomacromolecule crystallization and structural analysis by serial crystallographyDe Wijn, Raphäel; Henning, Oliver; Roche, Jennifer; Engilberge, Sylvain; Rollet, Kevin; Fernández Millán, Pablo; Brillet, Karl; Betat, Heike; Mörl, Mario; Roussel, Alain; Girard, Eric; Mueller Dieckmann, Christoph; Fox, Gavin C.; Olieric, Vincent; Gavira Gallardo, J. A. ; Lorber, Bernard; Sauter, Claudeartículo
3closedAccessaccesoRestringido.pdf.jpg2020Agarose Gel as a Medium for Growing and Tailoring Protein CrystalsArtusio, Fiora; Castellví, Albert CSIC ORCID; Sacristán, Anabel; Pisano, Roberto; Gavira Gallardo, J. A. artículo
4openAccessGavi_ActaCryst_D76_751.pdf.jpg27-Jul-2020Attaining atomic resolution from in situ data collection at room temperature using counter-diffusion-based low-cost microchipsGavira Gallardo, J. A. ; Rodríguez-Ruiz, I.; Martínez Rodríguez, Sergio; Basu, Shibom; Teychené, Sébastien; McCarthy, Andrew A.; Mueller-Dieckman, Christophartículo
5closedAccessOct-2005Binding curves by continuous gradient flow-mix calorimetryMartínez, José C.; López-Mayorga, Obdulio; Parody-Morreale, Antonio; Gavira Gallardo, J. A. artículo
6closedAccessMar-2006Capillary Crystallization and molecular replacement solution of Haemoglobin II of the Clam Lucina pectinataGavira Gallardo, J. A. ; Jesús, W. de; Cámara-Artigas, Ana; López-Garriga, J.; García Ruiz, Juan Manuel CSIC ORCIDartículo
7closedAccessaccesoRestringido.pdf.jpg7-Dec-2018Catalytic and Electron Conducting Carbon Nanotube–Reinforced Lysozyme CrystalsContreras Montoya, Rafael; Escolano, Gillermo; Roy, Subhasish; López López, Modesto; Delgado López, José Manuel CSIC ORCID; Cuerva, Juan M.; Díaz Mochón, Juan José; Ashkenasy, Nurit; Gavira Gallardo, J. A. ; Álvarez de Cienfuegos, Luisartículo
8openAccess2022_Matilla_mBio_OA.pdf.jpg2022Chemotaxis of the human pathogen Pseudomonas aeruginosa to the neurotransmitter AcetylcholineMatilla, Miguel A.; Velando, Félix; Tajuelo, Ana; Martín-Mora, David; Xu, Wenhao; Sourjik, Victor; Gavira Gallardo, J. A. ; Krell, Tinoartículo
9openAccessaccesoRestringido.pdf.jpg8-May-2020Coarse-grained molecular simulations of the binding of the SARS-CoV 2 spike protein RBD to the ACE2 cell receptorDe Sancho, David; Gavira Gallardo, J. A. ; Pérez-Jiménez, Raúlartículo
10openAccessJ_Mol_biol_433_2021_Gavira.pdf.jpg3-Dec-2021Combining Ancestral Reconstruction with Folding-Landscape Simulations to Engineer Heterologous Protein Expression: Engineering heterologous protein expressionGamiz-Arco, Gloria; Risso, Valeria A.; Gaucher, Eric A.; Gavira Gallardo, J. A. ; Naganathan, Athi N. CSIC ORCID; Ibarra-Molero, Beatriz; Sánchez-Ruiz, Jose M.artículo
11closedAccessJan-2008Crystallization and preliminary crystallographic studies of an active-site mutant hydantoin racemase from Sinorhizobium meliloti CECT4114.Martínez-Rodríguez, Sergio; González-Ramírez, L. A.; Clemente-Jiménez, J. M.; Rodríguez-Vico, F.; Las Heras-Vázquez, F. J.; Gavira Gallardo, J. A. ; García Ruiz, Juan Manuel CSIC ORCIDartículo
12closedAccessMay-2007Crystallization by capillary counter-diffusion and structure determination of the N114A mutant of the SH3 domain of Abl tyrosine kinase complexed with a high-affinity peptide ligandCámara-Artigas, Ana; Palencia, A.; Martínez, José C.; Luque, Irene; Gavira Gallardo, J. A. ; García Ruiz, Juan Manuel CSIC ORCIDartículo
13openAccessfulltext.pdf.jpg19-Sep-2008Crystallization of proteins on functionalized surfaces.Tosi, G.; Fermani, S.; Falini, G.; Gavira Gallardo, J. A. ; García Ruiz, Juan Manuel CSIC ORCIDartículo
14openAccessGavi ncomms16113.pdf.jpg18-Jul-2017De novo active sites for resurrected Precambrian enzymesRisso, Valeria A.; Martínez-Rodríguez, Sergio; Candel, Adela M.; Krüger, Dennis M.; Pantoja-Uceda, D.; Ortega-Muñoz, Mariano; Santoyo-González, Francisco; Gaucher, Eric A.; Kamerlin, Shina C.L.; Bruix, M. CSIC ORCID ; Gavira Gallardo, J. A. ; Sánchez López, Jose M.artículo
15openAccessScientific Report 9 3117.pdf.jpg28-Feb-2019Efficacy of aldose reductase inhibitors is affected by oxidative stress induced under X-ray irradiationCastellví, Albert CSIC ORCID; Crespo, Isidro; Crosas, Eva; Cámara-Artigas, Ana; Gavira Gallardo, J. A. ; Aranda, M. A. G.; Parés, Xavier; Juanhuix, J.artículo
16closedAccessaccesoRestringido.pdf.jpg31-Oct-2017Efficient Screening Methodology for Protein Crystallization Based on the Counter-Diffusion TechniqueGonzález-Ramírez, Luis A.; Ruiz-Martínez, Carlos R.; Estremera-Andújar, Rafael A.; Nieves-Marrero, Carlos A.; García Caballero, Alfonso; Gavira Gallardo, J. A. ; López-Garriga, J.; García Ruiz, Juan Manuel CSIC ORCIDartículo
17closedAccessaccesoRestringido.pdf.jpg21-May-2019Enhanced Stability against Radiation Damage of Lysozyme Crystals Grown in Fmoc-CF HydrogelsContreras Montoya, Rafael; Castellví, Albert CSIC ORCID; Escolano-Casado, Guillermo; Juanhuix, Judith; Conejero Muriel, Mayte CSIC ORCID; López López, Modesto; Cuerva, Juan M.; Álvarez de Cienfuegos, Luis; Gavira Gallardo, J. A. artículo
18openAccessGavi_JA_HumanMolGen26_3531.pdf.jpg6-Jul-2017Enhanced vulnerability of human proteins towards disease-associated inactivation through divergent evolutionMedina-Carmona, Encarnación; Fuchs, Julian E.; Gavira Gallardo, J. A. ; Mesa Torres, Noel; Neira, José L.; Salido, Eduardo; Palomino-Morales, Rogelio; Burgos, Miguel; Timson, David; Pey, Ángel L.artículo
19openAccessGavi_Chem._Sci_11_613.pdf.jpg19-May-2020Enhancing a: De novo enzyme activity by computationally-focused ultra-low-throughput screeningRisso, Valeria A.; Romero-Rivera, Adrian; Gutierrez-Rus, Luis I.; Ortega-Muñoz, Mariano; Santoyo-González, Francisco; Gavira Gallardo, J. A. ; Sanchez-Ruiz, José M.; Kamerlin, Shina C.L.artículo
20openAccessGarciaRuiz_PNAS109_18926.pdf.jpg13-Nov-2012Evidence for chemoreceptors with bimodular ligand binding regions harboring two signal binding sitesPineda-Molina, Estela; Reyes-Darias, José Antonio; Lacal, Jesús CSIC ORCID; Ramos, Juan L.; García Ruiz, Juan Manuel CSIC ORCID; Gavira Gallardo, J. A. ; Krell, Tinoartículo