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Browsing by Author Vitorica, Javier

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closedAccessaccesoRestringido.pdf.jpgMay-2010Activity-Dependent Neuroprotective Protein (ADNP) Expression in the Amyloid Precursor Protein/Presenilin 1 Mouse Model of Alzheimer’s DiseaseFernández Montesinos, Rafael CSIC; Torres, Manuel; Baglietto-Vargas, David; Gutiérrez, Antonia; Gozes, Illana; Vitorica, Javier CSIC ORCID; Pozo, David CSIC ORCIDartículo
openAccessjournal.pone.0170345.pdf.jpg18-Jan-2017Acute and Chronic Sustained Hypoxia Do Not Substantially Regulate Amyloid-β Peptide Generation In VivoSerrano-Pozo, Alberto; Sánchez García, Manuel A.; Heras-Garvin, Antonio CSIC; March Díaz, Rosana CSIC; Navarro-Garrido, Victoria; Vizuete, Marisa; López-Barneo, José CSIC ORCID; Vitorica, Javier CSIC ORCID; Pascual Bravo, Alberto CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2011Age-dependent accumulation of soluble amyloid ß (Aß) oligomers reverses the neuroprotective effect of soluble amyloid precursor protein-α (sAPPα) by modulating phosphatidylinositol 3-kinase (PI3K)/Akt-GSK- 3ß pathway in Alzheimer mouse model.Jiménez, Sebastián; Torres, Manuel; Vizuete, Marisa; Carmona-Cuenca, Irene; Caballero, Cristina; Ruano, Diego; Vitorica, Javier CSIC ORCIDartículo
openAccessdystrophic_synapses.pdf.jpgJan-2021Amyloid‐β impairs the phagocytosis of dystrophic synapses by astrocytes in Alzheimer's diseaseSánchez‐Mico, María V.; Jiménez, Sebastián; Gómez-Arboledas, Ángela; Muñoz-Castro, Clara; Romero-Molina, Carmen; Navarro-Garrido, Victoria; Sanchez‐Mejías, Elisabeth; Núñez-Díaz, Cristina; Sánchez-Varo, Raquel; Galea, Elena; Dávila, José C.; Vizuete, Marisa; Gutiérrez, Antonia; Vitorica, Javier CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpgSep-2014Chronic hypoxia aggravates Alzheimer’s disease pathology by causing microglial dysfunctionMarch Díaz, Rosana CSIC; Heras-Garvin, Antonio CSIC; Viehweger, Adrian; Jiménez, Sebastián; Serrano-Pozo, Alberto; Navarro-Garrido, Victoria; Gerpe, Almudena; Vizuete, Marisa; Gutiérrez, Antonia; López-Barneo, José CSIC ORCID; Berra, Edurne; Vitorica, Javier CSIC ORCIDpóster de congreso
openAccessjournal.pone.0181510.pdf.jpg26-Jul-2017Correction: Acute and Chronic Sustained Hypoxia Do Not Substantially Regulate Amyloid-β Peptide Generation In VivoSerrano-Pozo, Alberto; Sánchez García, Manuel A.; Heras-Garvin, Antonio CSIC; March Díaz, Rosana CSIC; Navarro-Garrido, Victoria; Vizuete, Marisa; López-Barneo, José CSIC ORCID; Vitorica, Javier CSIC ORCID; Pascual Bravo, Alberto CSIC ORCID artículo
openAccessSanchez-Mejias_et_al-2020.pdf.jpgMar-2020Distinct disease‐sensitive GABAergic neurons in the perirhinal cortex of Alzheimer's mice and patientsSánchez-Mejias, Elisabeth; Núñez-Díaz, Cristina; Sánchez-Varo, Raquel; Gómez-Arboledas, Ángela; García-León, Juan Antonio; Fernández-Valenzuela, Juan J.; Mejías-Ortega, Marina; Trujillo-Estrada, Laura; Baglietto-Vargas, David; Moreno-González, Inés; Dávila, José C.; Vitorica, Javier CSIC ORCID; Gutiérrez, Antoniaartículo
openAccessfncel-12-00421.pdf.jpg14-Nov-2018Distinct Microglial Responses in Two Transgenic Murine Models of TAU PathologyRomero-Molina, Carmen; Navarro-Garrido, Victoria; Sánchez-Varo, Raquel; Jiménez, Sebastián; Fernández-Valenzuela, Juan J.; Sánchez-Mico, María V.; Muñoz-Castro, Clara; Gutiérrez, Antonia; Vitorica, Javier CSIC ORCID; Vizuete, Marisaartículo
openAccesss41598-017-10353-7.pdf.jpg30-Aug-2017Dual roles of Aβ in proliferative processes in an amyloidogenic model of Alzheimer’s diseaseBaglietto-Vargas, David; Sánchez-Mejias, Elisabeth; Navarro-Garrido, Victoria; Jiménez, Sebastián; Trujillo-Estrada, Laura; Gómez-Arboledas, Ángela; Sánchez-Mico, María V.; Sánchez-Varo, Raquel; Vizuete, Marisa; Dávila, José C.; García-Verdugo, José Manuel; Vitorica, Javier CSIC ORCID; Gutiérrez, Antoniaartículo
closedAccess11-Sep-2009Dysfunction of the unfolded protein response increases neurodegeneration in aged rat hippocampus following proteasome inhibitionGavilán, María P. CSIC ORCID; Pintado, Cristina; Gavilán, Elena CSIC ORCID; Jiménez, Sebastián; Ríos, Rosa M. CSIC ORCID; Vitorica, Javier CSIC ORCID; Castaño, Angélica; Ruano, Diegoartículo
openAccessmicrotubule_stabilization.pdf.jpg8-Sep-2020Enhancing microtubule stabilization rescues cognitive deficits and ameliorates pathological phenotype in an amyloidogenic Alzheimer’s disease modelFernández-Valenzuela, Juan J.; Sánchez-Varo, Raquel; Muñoz-Castro, Clara; Castro, Vanessa de; Sánchez-Mejias, Elisabeth; Navarro-Garrido, Victoria; Jiménez, Sebastián; Núñez-Díaz, Cristina; Gómez-Arboledas, Ángela; Moreno-González, Inés; Vizuete, Marisa; Dávila, José C.; Vitorica, Javier CSIC ORCID; Gutiérrez, Antoniaartículo
openAccessBoza-Serrano2019_Article_Galectin.pdf.jpg20-Apr-2019Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer’s diseaseBoza-Serrano, Antonio; Ruiz, Rocío; Sánchez-Varo, Raquel; García-Revilla, Juan; Yang, Yiyi; Jiménez-Ferrer, Itzia; Paulus, Agnes; Wennström, Malin; Vilalta, Anna; Allendorf, David; Dávila, José C.; Stegmayr, John; Jiménez, Sebastián; Roca-Ceballos, María Angustias; Navarro-Garrido, Victoria; Swanberg, Maria; Hsieh, Christine L.; Real, Luis Miguel; Englund, Elisabet; Linse, Sara; Leffler, Hakon; Nilsson, Ulf J.; Brown, Guy Charles; Gutiérrez, Antonia; Vitorica, Javier CSIC ORCID; Venero, José L.; Deierborg, Tomasartículo
openAccessDrug_Screening.pdf.jpg18-Sep-2020Human Pluripotent Stem Cell-Derived Neural Cells as a Relevant Platform for Drug Screening in Alzheimer’s DiseaseGarcía-León, Juan Antonio; Cáceres-Palomo, Laura; Sánchez-Mejias, Elisabeth; Mejías-Ortega, Marina; Núñez-Díaz, Cristina; Fernández-Valenzuela, Juan J.; Sánchez-Varo, Raquel; Dávila, José C.; Vitorica, Javier CSIC ORCID; Gutiérrez, Antoniaartículo de revisión
openAccessMarch-Diaz_et_al_Preprint.pdf.jpg15-Apr-2021Hypoxia compromises the mitochondrial metabolism of Alzheimer’s disease microglia via HIF1March Díaz, Rosana CSIC; Lara-Ureña, Nieves; Romero-Molina, Carmen; Heras-Garvin, Antonio CSIC; Ortega de San Luis, Clara; Alvarez-Vergara, Maria I.; Sánchez García, Manuel A.; Sánchez-Mejias, Elisabeth; Dávila, José C.; Rosales-Nieves, Alicia E.; Forja, Cristina; Navarro-Garrido, Victoria; Gómez-Arboledas, Ángela; Sánchez-Mico, María V.; Viehweger, Adrian; Gerpe, Almudena; Hodson, Emma J.; Vizuete, Marisa; Bishop, Tammie; Serrano-Pozo, Alberto; López-Barneo, José CSIC ORCID; Berra, Edurne; Vitorica, Javier CSIC ORCID; Pascual Bravo, Alberto CSIC ORCID preprint
openAccess2051-5960-1-73.pdf.jpg12-Nov-2013In vivo modification of Abeta plaque toxicity as a novel neuroprotective lithium-mediated therapy for Alzheimer¿s disease pathologyTrujillo-Estrada, Laura; Jiménez, Sebastián; De Castro, Vanessa; Torres, Manuel; Baglietto-Vargas, David; Moreno-González, Inés; Navarro-Garrido, Victoria; Sánchez-Varo, Raquel; Sánchez-Mejias, Elisabeth; Dávila, José C.; Vizuete, Marisa; Gutiérrez, Antonia; Vitorica, Javier CSIC ORCIDartículo
openAccessInflammatory_2008.pdf.jpg5-Nov-2008Inflammatory Response in the Hippocampus of PS1M146L/APP751SL Mouse Model of Alzheimer's Disease: Age-Dependent Switch in the Microglial Phenotype from Alternative to ClassicJiménez, Sebastián; Baglietto-Vargas, David; Caballero, Cristina; Moreno-González, Inés; Torres, Manuel; Sánchez-Varo, Raquel; Ruano, Diego; Vizuete, Marisa; Gutiérrez, Antonia; Vitorica, Javier CSIC ORCIDartículo
openAccessfnagi-10-00140.pdf.jpg11-May-2018Microglia in Alzheimer’s Disease: Activated, Dysfunctional or DegenerativeNavarro-Garrido, Victoria; Sánchez-Mejias, Elisabeth; Jiménez, Sebastián; Muñoz-Castro, Clara; Sánchez-Varo, Raquel; Dávila, José C.; Vizuete, Marisa; Gutiérrez, Antonia; Vitorica, Javier CSIC ORCIDartículo
openAccessnonvesse.pdf.jpg25-May-2021Non-productive angiogenesis disassembles Aß plaque-associated blood vesselsAlvarez-Vergara, Maria I.; Rosales-Nieves, Alicia E.; March-Diaz, Rosana; Rodriguez-Perinan, Guiomar; Lara-Ureña, Nieves; Ortega-de San Luis, Clara; Sanchez-Garcia, Manuel A.; Martin-Bornez, Miguel; Gómez-Gálvez, Pedro; Vicente-Munuera, Pablo; Fernandez-Gomez, Beatriz; Marchena, Miguel A.; Bullones-Bolanos, Andrea S.; Dávila, José C.; González-Martínez, Rocio; Trillo-Contreras, José Luis; Sanchez-Hidalgo, Ana C.; Toro, Raquel del; Scholl, Francisco G.; Herrera, Eloisa CSIC ORCID ; Trepel, Martin; Körbelin, Jakob; Escudero, Luis M. CSIC ORCID; Villadiego, Javier; Echevarria, Miriam; Castro Soubriet, Fernando de CSIC ORCID; Gutiérrez, Antonia; Rábano, Alberto; Vitorica, Javier CSIC ORCID; Pascual Bravo, Alberto CSIC ORCID artículo
openAccessPathology_Analysis.pdf.jpg4-Nov-2021Plaque-Associated Oligomeric Amyloid-Beta Drives Early Synaptotoxicity in APP/PS1 Mice Hippocampus: Ultrastructural Pathology AnalysisSánchez-Varo, Raquel; Sánchez-Mejias, Elisabeth; Fernández-Valenzuela, Juan José; Castro, Vanessa de; Mejías-Ortega, Marina; Gómez-Arboledas, Ángela; Jiménez, Sebastián; Sánchez-Mico, María Virtudes; Trujillo-Estrada, Laura; Moreno-González, Inés; Baglietto-Vargas, David; Vizuete, Marisa; Dávila, José Carlos; Vitorica, Javier CSIC ORCID; Gutiérrez, Antoniaartículo
openAccessregional_difference_inflammatory_pintado.pdf.jpg2011Regional difference in inflammatory response to LPS-injection in the brain: Role of microglia cell densityPintado, Cristina; Revilla, Elisa; Vizuete, Marisa; Jiménez, Sebastián; García Cuervo, Luisa; Vitorica, Javier CSIC ORCID; Ruano, Diego; Castaño, Angélicaartículo