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openAccessproceedings-22-00108 (1).pdf.jpg15-May-20194,4-Disubstituted N-benzylpiperidines: a novel class of fusion inhibitors of influenza virus H1N1 targeting a new binding site in hemagglutininCastro, Sonia de; Vanderlinden, E.; Ginex, Tiziana CSIC ORCID ; Laporte, M.; Stevaert, L.; Naesens, L.; Luque, F. Javier; Camarasa Rius, María José CSIC ORCID; Velázquez, Sonsoles CSIC ORCID CVNcomunicación de congreso
closedAccess1998Abasic analogues of TSAO-T as the first sugar derivatives that specifically inhibit HIV-1 reverse transcriptaseVelázquez, Sonsoles CSIC ORCID CVN; Chamorro, Cristina; Pérez Pérez, María Jesús; Alvarez, Rosa; Jimeno, M. Luisa; Martín Domenech, Angel; Pérez, Carlos; Gago, Federico; De Clercq, Erik; Balzarini, Jan; San-Félix, Ana CSIC ORCID CVN; Camarasa Rius, María José CSIC ORCIDartículo
openAccessOncotarget.pdf.jpg20-May-2016Antivascular and antitumor properties of the tubulin-binding chalcone TUB091Canela, María-Dolores CSIC; Noppen, Sam; Bueno, Oskía; Prota, Andrea E.; Bargsten, Katja; Sáez-Calvo, Gonzalo; Jimeno, M. Luisa CSIC ORCID; Benkhei, Mohammed; Ribatti, Domenico; Velázquez, Sonsoles CSIC ORCID CVN; Camarasa Rius, María José CSIC ORCID; Díaz, José Fernando CSIC ORCID ; Steinmetz, Michel O.; Priego, Eva María CSIC ORCID; Peréz-Pérez, María-Jesús CSIC ORCID ; Liekens, Sandraartículo
openAccessMJC-4.pdf.jpg2015Comparison of hydrocarbon-and lactam-bridged cyclic peptides as dimerization inhibitors of Leishmania infantum trypanothione reductaseSánchez-Murcia, Pedro A. CSIC ORCID; Ruiz-Santaquiteria, Marta CSIC ORCID; Toro, Miguel A.; Lucio, H. de; Jiménez, M. Angeles CSIC ORCID ; Gago, Federico CSIC ORCID; Jiménez-Ruiz, Antonio; Camarasa Rius, María José CSIC ORCID; Velázquez, Sonsoles CSIC ORCID CVNartículo
closedAccess2011Dipeptidyl peptidase IV dependent water-soluble prodrugs of highly lipophilic bicyclic nucleoside analoguesDiez-Torrubia, Alberto CSIC; Balzarini, Jan; Andrei, G; Snoeck, R.; De Meester, Ingrid; Camarasa Rius, María José CSIC ORCID; Velázquez, Sonsoles CSIC ORCID CVNartículo
closedAccess2012Dipeptidyl Peptidase IV-Activated Prodrugs of Anti- Varicella Zoster Virus Bicyclic Nucleoside Analogues Containing Different Self-Cleavage Spacer SystemsDiez-Torrubia, Alberto CSIC; Cabrera, Silvia CSIC ORCID; De Meester, Ingrid; Camarasa Rius, María José CSIC ORCID; Balzarini, Jan; Velázquez, Sonsoles CSIC ORCID CVNartículo
openAccessMJC-2.pdf.jpg2015Dipeptidyl-peptidase IV (DPP IV/CD26)-activated prodrugs: A successful strategy for improving water solubility and oral bioavailabilityVelázquez, Sonsoles CSIC ORCID CVN; Castro, Sonia de; Diez-Torrubia, Alberto CSIC; Balzarini, Jan; Camarasa Rius, María José CSIC ORCIDartículo
closedAccess3-Feb-2012Dipeptidyl-peptidase IV (DPPIV/CD26)-based prodrugs of hydroxy-containing drugsDiez-Torrubia, Alberto CSIC; Cabrera, Silvia CSIC ORCID; Lambeir, Anne-Marie; Balzarini, Jan; Camarasa Rius, María José CSIC ORCID; Velázquez, Sonsoles CSIC ORCID CVNartículo
closedAccessaccesoRestringido.pdf.jpg2014Discovery and SAR studies of a novel class of cytotoxic 1,4-disubstituted piperidines via Ugi reactionCastro, Sonia de; Camarasa Rius, María José CSIC ORCID; Balzarini, Jan; Velázquez, Sonsoles CSIC ORCID CVNartículo
openAccess556-1027-1-PB-3.pdf.jpg2014Diseño y desarrollo de una novedosa estrategia profármaco basada en la enzima DPPIV/CD26Camarasa Rius, María José CSIC ORCID; Castro, Sonia de; Velázquez, Sonsoles CSIC ORCID CVNartículo
openAccessacs.jmedchem.1c00206.pdf.jpg2021Efficient Dimerization Disruption of Leishmania infantum Trypanothione Reductase by Triazole-phenyl-thiazolesRevuelto, Alejandro; Lucio, Héctor de; García-Soriano, Juan Carlos; Sánchez-Murcia, Pedro A. CSIC ORCID; Gago, Federico CSIC ORCID; Jiménez-Ruiz, Antonio; Camarasa Rius, María José CSIC ORCID; Velázquez, Sonsoles CSIC ORCID CVNartículo
openAccessaccesoRestringido.pdf.jpg2017First example of peptides targeting the dimer interface of Leishmania infantum trypanothione reductase with potent in vitro antileishmanial activity#Ruiz-Santaquiteria, Marta CSIC ORCID; Sánchez-Murcia, Pedro A. CSIC ORCID; Toro, Miguel A.; Lucio, H. de; Gutierrez, Kilian Jesús.; Castro, Sonia de; Carneiro, Filipa A. C.; Gago, Federico; Jiménez-Ruiz, Antonio; Camarasa Rius, María José CSIC ORCID; Velázquez, Sonsoles CSIC ORCID CVNartículo
closedAccess2011From β-Amino-γ-sultone to Unusual Bicyclic Pyridine and Pyrazine Heterocyclic Systems: Synthesis and Cytostatic and Antiviral ActivitiesCastro, Sonia de; Familiar, Olga CSIC; Andrei, G; Snoeck, R.; Balzarini, Jan; Camarasa Rius, María José CSIC ORCID; Velázquez, Sonsoles CSIC ORCID CVNartículo
closedAccess2000HIV-1 specific reverse transcriptase inhibitors: Why are TSAO-nucleosides so unique?Camarasa Rius, María José CSIC ORCID; San-Felix, Alejandra; Pérez Pérez, María Jesús; Velázquez, Sonsoles CSIC ORCID CVN; Álvarez, Rosa; Chamorro, Cristina; Jimeno, M. Luisa CSIC ORCID; Perez, Carlos; Gago, Federico CSIC ORCID; De Clercq, Erik; Balzarini, Janartículo
openAccessSV-EJMC 2017- preprint.pdf.jpg21-Sep-2017Improved proteolytic stability and potent activity against Leishmania infantum trypanothione reductase of α/β-peptide foldamers conjugated to cell-penetrating peptidesLucio, Héctor de; Gamo, Ana María CSIC; Ruiz-Santaquiteria, Marta CSIC ORCID; Castro, Sonia de; Sánchez-Murcia, Pedro A. CSIC ORCID; Toro, Miguel A.; Gutiérrez, Kilian Jesús; Gago, Federico CSIC ORCID; Jiménez- Ruiz, Antonio; Camarasa Rius, María José CSIC ORCID; Velázquez, Sonsoles CSIC ORCID CVNartículo
openAccessWO2009030410A1.pdf.jpg12-Mar-2009Improvements in or relating to compositions for the treatment or prophylaxis of viral infectionsBalzarini, Jan; Camarasa Rius, María José CSIC ORCID; Velázquez, Sonsoles CSIC ORCID CVNpatente
openAccessSVelazquez_manuscript-ACSID 2020_compressed.pdf.jpg2020N-benzyl 4,4-disubstituted piperidines as a potent class of influenza H1N1 virus inhibitors showing a novel mechanism of hemagglutinin fusion peptide interactionCastro, Sonia de; Ginex, Tiziana CSIC ORCID ; Vanderlinden, E.; Laporte, M.; Stevaert, A.; Cumella, José; Gago, F.; Camarasa Rius, María José CSIC ORCID; Luque, F. J.; Naesens, L.; Velázquez, Sonsoles CSIC ORCID CVNartículo
closedAccess2013Novel water-soluble prodrugs of acyclovir cleavable by the dipeptidyl-peptidase IV (DPP IV/CD26) enzymeDiez-Torrubia, Alberto CSIC; Cabrera, Silvia CSIC ORCID; Castro, Sonia de; García-Aparicio, Carlos CSIC; Mulder, Gwenn; De Meester, Ingrid; Camarasa Rius, María José CSIC ORCID; Balzarini, Jan; Velázquez, Sonsoles CSIC ORCID CVN; Diez-Torrubia, Alberto CSICartículo
openAccessWO2021099659A1.pdf.jpg27-May-2021Peptides containing -Dalanine (D-ala) or related amino alcoholsGarcía del Portillo, Francisco CSIC ORCID ; Rico Pérez, Gadea; Ramos Marquès, Estel; San-Félix, Ana CSIC ORCID CVN; Velázquez, Sonsoles CSIC ORCID CVN; Puente-Secades, Sofía de la; García Doyagüez, Elisasolicitud de patente
openAccessACSMCL2020_RT-dimeriz-inhibs-3(revised-for publication).pdf.jpg2020Peptides mimicking the β7/β8 loop of HIV'1 reverse transcriptase p51 as “hotspot-targeted” dimerization inhibitorsSánchez-Murcia, Pedro A. CSIC ORCID; Castro, Sonia de; García-Aparicio, Carlos CSIC; Jiménez, M. Angeles CSIC ORCID ; Corona, A.; Tramontano, Enzo; Sluis-Cremer, N.; Menéndez-Arias, Luis CSIC ORCID ; Velázquez, Sonsoles CSIC ORCID CVN; Gago, Federico CSIC ORCID; Camarasa Rius, María José CSIC ORCIDartículo