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Browsing by Author Varela, Ignacio

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RightsPreviewIssue DateTitleAuthor(s)Type
openAccessfunctionalTLR10.pdf.jpg2016A functional variant of TLR10 modifies the activity of NFkB and may help predict a worse prognosis in patients with rheumatoid arthritisTorices, Silvia; Varela, Ignacio CSIC ORCID; Fernández-Luna, J. L.artículo
openAccessBrafV600E.pdf.jpg2013A genetic progression model of BrafV600E-induced intestinal tumorigenesis reveals targets for therapeutic interventionRad, Roland; Varela, Ignacio CSIC ORCID; Calvanese, Vincenzo; Bradley, Allanartículo
openAccesspancreaticancer.pdf.jpg2014A next-generation dual-recombinase system for time and host specific targeting of pancreatic cancerSchönhuber, Nina; Varela, Ignacio CSIC ORCID; Saur, Dieterartículo
closedAccessaccesoRestringido.pdf.jpg2014A novel mutation in ADAMTS13 of a child with Upshaw-Schulman SyndromePérez-Rodríguez, A.; Batlle-López, Ana; Blanco, Rosa CSIC; Varela, Ignacio CSIC ORCID; León, Javier CSIC ORCID CVN; Delgado, M. Dolores CSIC ORCID; López-Fernández, M. F.artículo
closedAccessaccesoRestringido.pdf.jpg2020A spotlight on cancer researchers in Spain: new paradigms and disruptive ideasRamón y Cajal, S.; Sancho, P.; Soucek, L.; Peinado, H.; Abad, M.; Valiente, M.; Efeyan, A.; Pardo, J.; Quesada, V.; Jimeno, J.; Duque, P. M.; Antón, A.; Varela, Ignacio CSIC ORCID; Schuhmacher, A. J.editorial
closedAccessaccesoRestringido.pdf.jpg2016Activated KRAS cooperates with MLLAF4 to promote extramedullary engraftment and migration of cord blood CD34+ HSPC but is insufficient to initiate leukemiaPrieto, Cristina; Agraz-Doblas, Antonio; Varela, Ignacio CSIC ORCID; Menendez, Pabloartículo
openAccessclaritychallenge.pdf.jpg2014An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY ChallengeBrownstein, Catherine A.; Beggs, Alan H.; Barrera, Jorge CSIC ORCID; García-Lobo, Juan M. CSIC ORCID; González-Lamuño, Domingo; Llorca, Javier; Rodríguez, María Cruz CSIC; Varela, Ignacio CSIC ORCID; Kohane, Isaac S.; Margulies, David M.artículo
openAccessanalytarge.pdf.jpg2017Analysis of the mutational landscape of classic Hodgkin lymphoma identifies disease heterogeneity and potential therapeutic targetsMata, Elena; Sánchez-Beato, Margarita; Varela, Ignacio CSIC ORCID; Piris, Miguel A.; García, Juan F.artículo
closedAccessaccesoRestringido.pdf.jpg2020Analysis pipelines for cancer genome sequencing in miceLange, Sebastian; Engleitner, Thomas; Mueller, Sebastian; Maresch, Roman; Zwiebel, Maximilian; González-Silva, Laura; Schneider, Günter; Banerjee, Ruby; Yang, Fengtang; Vassiliou, George S.; Friedrich, Mathias; Saur, Dieter; Varela, Ignacio CSIC ORCID; Rad, Rolandartículo
openAccessBone_Diaz_Art2020.pdf.jpg2020Bone marrow clonogenic myeloid progenitors from NPM1-mutated AML patients do not harbor the NPM1 mutation: Implication for the cell-of-origin of NPM1+ AMLDíaz de la Guardia, Rafael; González-Silva, Laura; López-Millán, Belén; Rodríguez-Sevilla, Juan José; Baroni, Matteo L.; Bueno, Clara; Anguita, Eduardo; Vives, Susana; Palomo, Laura; Lapillonne, Helene; Varela, Ignacio CSIC ORCID; Menéndez, Pabloartículo
openAccessCD133-directed_Bueno_Art2019.pdf.jpg2019CD133-directed CAR T-cells for MLL leukemia: on-target, off-tumor myeloablative toxicityBueno, Clara; Velasco-Hernández, Talia CSIC ORCID; Gutiérrez-Agüera, Francisco; Zanetti, Samanta Romina; Baroni, Matteo L.; Sánchez-Martínez, Diego; Molina, Oscar; Closa, Adria; Agraz-Doblas, Antonio; Marín, Pedro; Eyras, Eduardo; Varela, Ignacio CSIC ORCID; Menendez, Pabloartículo
openAccessClonal_Collord_PV_Art2018.pdf.jpgMay-2018Clonal haematopoiesis is not prevalent in survivors of childhood cancerCollord, Grace; Park, Naomi; Podestà, Marina; Dagnino, Monica; Cilloni, Daniela; Jones, David; Varela, Ignacio CSIC ORCID; Frassoni, Francesco; Vassiliou, George S.artículo
openAccessAdenocarcinoma Specimens.PDF.jpg2015Colorectal adenomas contain multiple somatic mutations that do not coincide with synchronous adenocarcinoma specimensVaqué, José P.; Varela, Ignacio CSIC ORCID; Moreno, Thaidy; Piris, Miguel A.artículo
openAccesstargeted DNA capture.pdf.jpg2013Detailed molecular characterisation of acute myeloid leukaemia with a normal karyotype using targeted DNA captureVarela, Ignacio CSIC ORCID; Moreno, Teresa CSIC ORCID ; Rad, Roland; Vassiliou, George S.artículo
closedAccessaccesoRestringido.pdf.jpg2016Development and validation of a comprehensive genomic diagnostic tool for myeloid malignanciesMcKerrell, Thomas; Moreno, Thaidy; Varela, Ignacio CSIC ORCID; Vassiliou, George S.artículo
closedAccessaccesoRestringido.pdf.jpg2016Development of new cell genetic tracing tools for the study of intratumour heterogeneityQuevedo, Laura; González-Silva, Laura; Moreno, Thaidy; Revilla, Carlos CSIC; Saur, Dieter; Rad, Roland; Varela, Ignacio CSIC ORCIDpóster de congreso
openAccesssynchronous VHL.pdf.jpg2014Development of synchronous VHL syndrome tumors reveals contingencies and constraints to tumor evolution.Fisher, Rosalie; Gerlinger, Marco; Varela, Ignacio CSIC ORCID; Swanton, Charlesartículo
openAccessdevelopluri.pdf.jpg2016Development refractoriness of MLL-rearranged human B cell acute leukemias to reprogramming into pluripotencyMuñoz-López, Alvaro; Prieto, Cristina; Agraz-Doblas, Antonio; Varela, Ignacio CSIC ORCID; Menendez, Pabloartículo
closedAccessaccesoRestringido.pdf.jpg26-Sep-2019Discovery of a CD10-negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programsO’Byrne, Sorcha; Elliott, Natalina; Rice, Siobhan; Buck, Gemma; Fordham, Nicholas; Garnett, Catherine; Godfrey, Laura; Crump, Nicholas T.; Wright, Gary; Inglott, Sarah; Hua, Peng; Psaila, Bethan; Povinelli, Benjamin; Knapp, David J. H. F.; Agraz-Doblas, Antonio; Bueno, Clara; Varela, Ignacio CSIC ORCID; Bennett, Phillip; Koohy, Hashem; Watt, Suzanne M.; Karadimitris, Anastasios; Mead, Adam J.; Ancliff, Phillip; Vyas, Paresh; Menéndez, Pablo; Milne, Thomas A.; Roberts, Irene; Roy, Aninditaartículo
openAccessEnhanced_Bueno_Art2019.pdf.jpgJun-2019Enhanced hemato-endothelial specification during human embryonic differentiation through developmental cooperation between AF4-MLL and MLL-AF4 fusionsBueno, Clara; Calero-Nieto, Fernando J.; Wang, Xiaonan; Valdés-Mas, Rafael; Gutiérrez-Agüera, Francisco; Roca-Ho, Heleia; Ayllón, Verónica; Real, Pedro J.; Arambilet, David; Espinosa, Lluis; Torres-Ruiz, Raul; Agraz-Doblas, Antonio; Varela, Ignacio CSIC ORCID; Boer, Jasper de; Bigas, Anna; Gottgens, Bertie; Marschalek, Rolf; Menendez, Pabloartículo