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DerechosPreviewFecha Public.TítuloAutor(es)Tipo
openAccessSystematic_Approach_Uribe.pdf.jpg18-dic-2021A Systematic Approach to Assess the Activity and Classification of PCSK9 VariantsUribe, Kepa B. CSIC ORCID; Chemello, Kevin; Larrea, Asier CSIC ORCID; Benito-Vicente, Asier CSIC ORCID; Galicia-García, Unai CSIC ORCID; Bourane, Steeve; Jaafar, Ali K.; Lambert, Gilles; Martín, César CSIC ORCIDartículo
openAccessBoosting_Cholesterol_Jebari.pdf.jpg1-abr-2022Boosting Cholesterol Efflux from Foam Cells by Sequential Administration of rHDL to Deliver MicroRNA and to Remove Cholesterol in a Triple-Cell 2D Atherosclerosis ModelJebari-Benslaiman, Shifa CSIC ORCID CVN; Uribe, Kepa B. CSIC ORCID; Benito-Vicente, Asier CSIC ORCID; Galicia-García, Unai CSIC ORCID; Larrea, Asier CSIC ORCID; Santin, Izortze; Alloza, Iraide; Vanderbroeck, Koen; Ostolaza, Helena CSIC ORCID; Martín, César CSIC ORCIDartículo
openAccessCholesterol_Efflux_Jebari_Benslaiman.pdf.jpgoct-2020Cholesterol Efflux Efficiency of Reconstituted HDL Is Affected by Nanoparticle Lipid CompositionJebari-Benslaiman, Shifa CSIC ORCID CVN; Uribe, Kepa B. CSIC ORCID; Benito-Vicente, Asier CSIC ORCID; Galicia-García, Unai CSIC ORCID; Larrea, Asier CSIC ORCID; Alloza, Iraide; Vandenbroeck, Koen; Ostolaza, Helena CSIC ORCID; Martín, César CSIC ORCIDartículo
openAccessCholesterol_stimulates_Gonzalez.pdf.jpgdic-2021Cholesterol stimulates the lytic activity of Adenylate Cyclase Toxin on lipid membranes by promoting toxin oligomerization and formation of pores with a greater effective sizeGonzález‐Bullón, David CSIC ORCID; Uribe, Kepa B. CSIC ORCID; Amuategi, Jone CSIC ORCID; Martín, César CSIC ORCID; Ostolaza, Helena CSIC ORCIDartículo
closedAccessAcceso_restringido.pdf.jpgjun-2023Contribution of APOE Genetic Variants to DyslipidemiaBea, Ana M.; Larrea, Asier CSIC ORCID; Marco Benedí, Victoria; Uribe, Kepa B. CSIC ORCID; Galicia-García, Unai CSIC ORCID; Lamiquiz-Moneo, Itziar; Laclaustra, Martín; Moreno-Franco, Belén; Fernández-Corredoira, Pablo; Olmos, Salvador; Civeira, Fernando; Martín, César CSIC ORCID; Cenarro, Anaartículo
closedAccessAcceso_restringido.pdf.jpgjul-2022Leu22_Leu23 Duplication at the Signal Peptide of PCSK9 Promotes Intracellular Degradation of LDLr and Autosomal Dominant HypercholesterolemiaBenito-Vicente, Asier CSIC ORCID; Uribe, Kepa B. CSIC ORCID; Larrea, Asier CSIC ORCID; Palacios, Lourdes; Cenarro, Ana; Calle, Xabier; Galicia-García, Unai CSIC ORCID; Jebari-Benslaiman, Shifa CSIC ORCID CVN; Sánchez-Hernández, Rosa M.; Stef, Marianne; Lambert, Gilles; Civeira, Fernando; Martín, César CSIC ORCIDartículo
openAccessMLb_LDLr_Larrea.pdf.jpgnov-2021MLb-LDLr: A Machine Learning Model for Predicting the Pathogenicity of LDLr Missense VariantsLarrea, Asier CSIC ORCID; Benito-Vicente, Asier CSIC ORCID; Fernández-Higuero, José Ángel CSIC ORCID; Jebari-Benslaiman, Shifa CSIC ORCID CVN; Galicia-García, Unai CSIC ORCID; Uribe, Kepa B. CSIC ORCID; Cenarro, Ana; Ostolaza, Helena CSIC ORCID; Civeira, Fernando; Arrasate, Sonia; González-Díaz, Humberto CSIC ORCID; Martín, César CSIC ORCIDartículo
openAccessMutation_type_Galicia_Garcia.pdf.jpg3-feb-2020Mutation type classification and pathogenicity assignment of sixteen missense variants located in the EGF-precursor homology domain of the LDLRGalicia-García, Unai CSIC ORCID; Benito-Vicente, Asier CSIC ORCID; Uribe, Kepa B. CSIC ORCID; Jebari-Benslaiman, Shifa CSIC ORCID CVN; Larrea, Asier CSIC ORCID; Alonso-Estrada, Rocío CSIC; Aguilo-Arce, Joseba; Ostolaza, Helena CSIC ORCID; Palacios, Lourdes; Martín, César CSIC ORCIDartículo
closedAccessAcceso_restringido.pdf.jpgfeb-2021Novel PCSK9 (Proprotein Convertase Subtilisin Kexin Type 9) Variants in Patients With Familial Hypercholesterolemia From Cape TownHuijgen, Roeland; Blom, Dirk; Hartgers, Merel L.; Chemello, Kevin; Benito-Vicente, Asier CSIC ORCID; Uribe, Kepa B. CSIC ORCID; Behardien, Zorena; Blackhurst, Dee M.; Brice, Brigitte C.; Defesche, Joep C.; Jong, Annemiek G. de; Jooste, Rosemary J.; Solomon, Gabriele A. E.; Wolmarans, Karen H.; Kees Hovingh, G.; Martín, César CSIC ORCID; Lambert, Gilles; Marais, A. Davidartículo
openAccessPredictive-Modeling_CAR_2023_OA.pdf.jpgnov-2023Predictive Modeling and Structure Analysis of Genetic Variants in Familial Hypercholesterolemia: Implications for Diagnosis and Protein Interaction StudiesLarrea, Asier CSIC ORCID; Jebari-Benslaiman, Shifa CSIC ORCID CVN; Galicia-García, Unai CSIC ORCID; San Jose-Urteaga, Ane; Uribe, Kepa B. CSIC ORCID; Benito-Vicente, Asier CSIC ORCID; Martín, César CSIC ORCIDartículo de revisión
openAccess(r)HDL_Uribe.pdf.jpg7-may-2021(r)HDL in theranostics: how do we apply HDL's biology for precision medicine in atherosclerosis management?Uribe, Kepa B. CSIC ORCID; Benito-Vicente, Asier CSIC ORCID; Martín, César CSIC ORCID; Blanco-Vaca, Francisco; Rotllan, Noemíartículo de revisión
openAccessO-glycosylation.pdf.jpg11-may-2018Site-specific O-glycosylation of members of the low-density lipoprotein receptor superfamily enhances ligand interactionsWang, Shengjun; Mao, Yang; Narimatsu, Yoshiki; Ye, Zilu; Tian, Weihua; Goth, Christoffer K.; Lira-Navarrete, Erandi; Pedersen, Nis B.; Benito-Vicente, Asier CSIC ORCID; Martín, César CSIC ORCID; Uribe, Kepa B. CSIC ORCID; Hurtado-Guerrero, Ramón CSIC ORCID; Christoffersen, Christina; Seidah, Nabil G.; Nielsen, R.; Christensen, Erik I.; Hansen, Lars; Bennett, Eric P.; Vakhrushev, Sergey Y.; Schjoldager, Katrine T.; Clausen, Henrikartículo
closedAccessAcceso_restringido.pdf.jpgjul-2022Supplemental Material Leu22_Leu23 duplication at the signal peptide of PCSK9 promotes intracellular degradation of LDLr and autosomal dominant hypercholesterolemiaBenito-Vicente, Asier CSIC ORCID; Uribe, Kepa B. CSIC ORCID; Larrea, Asier CSIC ORCID; Palacios, Lourdes; Cenarro, Ana; Calle, Xabier; Galicia-García, Unai CSIC ORCID; Jebari-Benslaiman, Shifa CSIC ORCID CVN; Sánchez-Hernández, Rosa M.; Stef, Marianne; Lambert, Gilles; Civeira, Fernando; Martín, César CSIC ORCIDdataset
openAccessSupporting_information_Boosting_Cholesterol.pdf.jpg1-abr-2022Supporting Information for Small, DOI: 10.1002/smll.202105915 Boosting Cholesterol Efflux from Foam Cells by Sequential Administration of rHDL to Deliver MicroRNA and to Remove Cholesterol in a Triple-Cell 2D Atherosclerosis ModelJebari-Benslaiman, Shifa CSIC ORCID CVN; Uribe, Kepa B. CSIC ORCID; Benito-Vicente, Asier CSIC ORCID; Galicia-García, Unai CSIC ORCID; Larrea, Asier CSIC ORCID; Santin, Izortze; Alloza, Iraide; Vanderbroeck, Koen; Ostolaza, Helena CSIC ORCID; Martín, César CSIC ORCIDdataset