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Browsing by Author Trigili, Chiara

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Showing results 1 to 18 of 18
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closedAccessaccesoRestringido.pdf.jpg14-Jun-2011Corrigendum: Mechanism of Action of the Cytotoxic Macrolides Amphidinolide X and JTrigili, Chiara CSIC; Pera, Benet CSIC; Barbazanges, Marion; Cossy, Janine; Meyer, Christophe; Pineda, Oriol; Rodríguez-Escrich, Carles; Urpí, Félix; Vilarrasa, Jaume; Díaz, José Fernando CSIC ORCID ; Barasoain, Isabel CSIC corrigenda
closedAccessMay-2011Design and Synthesis of Pironetin Analogues with Simplified Structure and Study of Their Interactions with MicrotubulesMarco, J. Alberto; García-Pla, Jorge; Carda, Miguel; Murga, Juan; Falomir, Eva; Trigili, Chiara CSIC; Notararigo, Sara CSIC; Díaz, José Fernando CSIC ORCID ; Barasoain, Isabel CSIC artículo
closedAccess15-Aug-2011Effects of C7 Substitutions in a High Affinity Microtubule-Binding Taxane on Antitumor Activity and Drug TransportXiao, Xi; Wu, Ju; Trigili, Chiara CSIC; Chen, Hui; Chu, Joseph W.K.; Zhao, Ying; Lu, Peihua; Sheng, Li; Li, Yan; Sharom, Frances J.; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Fang, Wei-shuo S.artículo
openAccessTesis_Chiara_Trigili_2013.pdf.jpg2013Estudio y caracterización del mecanismo de acción bioquímico y celular de compuestos antitumorales dirigidos contra el citoesqueletoTrigili, Chiara CSICtesis doctoral
closedAccessrestringido.pdf.jpgMay-2011Highly Stereoselective Total Synthesis of (+)-9-epi-Dictyostatin and (–)-12,13-bis-epi-Dictyostatin Eur. JZanato, Chiara; Pignataro, Luca; Ambrosi, Andrea; Hao, Zhongyan; Trigili, Chiara CSIC; Díaz, José Fernando CSIC ORCID ; Barasoain, Isabel CSIC ; Gennari, Cesareartículo
openAccess2011 Canales_et_al.pdf.jpg19-Aug-2011Insights into the interaction of discodermolide and docetaxel with tubulin. Mapping the binding sites of microtubule-stabilizing agents by using an integrated NMR and computational approachCanales, Ángeles CSIC ORCID; Rodríguez-Salarichs, Javier; Trigili, Chiara CSIC; Nieto, Lidia CSIC; Coderch, Claire; Andreu, José Manuel CSIC ORCID ; Paterson, Ian; Jiménez-Barbero, Jesús CSIC ORCID; Díaz, José Fernando CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg1-Jun-2011Mecanismo de accion de los macrolidos citotoxicos amphinolidas X y JTrigili, Chiara CSIC; Pera, Benet CSIC; Barbazanges, Marion; Cossy, Janine; Meyer, Christophe; Pineda, Oriol; Rodríguez-Escrich, Carles; Urpí, Félix; Vilarrasa, Jaume; Díaz, José Fernando CSIC ORCID ; Barasoain, Isabel CSIC póster de congreso
closedAccess2-May-2011Mechanism of Action of Cytotoxic Macrolides Amphidinolide X and J.Trigili, Chiara CSIC; Pera, Benet CSIC; Barbazanges, Marion; Cossy, Janine; Meyer, Christophe; Pineda, Oriol; Rodríguez-Escrich, Carles; Urpí, Félix; Vilarrasa, Jaume; Díaz, José Fernando CSIC ORCID ; Barasoain, Isabel CSIC artículo
closedAccess16-Aug-2010Molecular recognition of peloruside A by microtubules. The C24 primary alcohol is essential for biological activity.Pera, Benet CSIC; Razzak, Mina; Trigili, Chiara CSIC; Pineda, Oriol; Canales, Ángeles CSIC ORCID; Martínez Buey, Rubén CSIC ORCID CVN; Jiménez-Barbero, Jesús CSIC ORCID; Northcote, Peter; Paterson, Ian; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg26-Mar-2010Probing the Pore Drug Binding Site of Microtubules with Fluorescent Taxanes: Evidence of Two Binding PosesBarasoain, Isabel CSIC ; García-Carril, Ana M.; Matesanz, Ruth CSIC ; Maccari, Giorgio; Trigili, Chiara CSIC; Mori, Mattia; Shi, Jing-Zhe; Fang, Wei-shuo S.; Andreu, José Manuel CSIC ORCID ; Botta, Maurizio; Díaz, José Fernando CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg13-Dec-2016Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer CellsTrigili, Chiara CSIC; Barasoain, Isabel CSIC ; Sánchez-Murcia, Pedro A. CSIC ORCID; Bargsten, Katja; Redondo-Horcajo, Mariano CSIC ORCID ; Nogales, Aurora CSIC ORCID; Gardner, Nicola M.; Meyer, Arndt; Naylor, Guy J.; Gomez-Rubio, Elena; Gago, Federico CSIC ORCID; Steinmetz, Michel O.; Paterson, Ian; Prota, Andrea E.; Díaz, José Fernando CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpgNov-2012Structure-activity relationships of novel substituted naphthalene diimides as anticancer agentsMilelli, Andrea; Tumiatti, Vicenzo; Micco, Marialuisa; Rosini, Michela; Zuccari, Guendalina; Raffaghello, Lizzia; Bianchi, Giovanna; Pistoia, Vito; Pistoia, Vito; Díaz, José Fernando CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Pera, Benet CSIC; Trigili, Chiara CSIC; Barasoain, Isabel CSIC ; Musetti, Caterina; Toniolo, Marianna; Sissi. Claudia; Alcaro, Stefano; Moraca, Federica; Zini, Maddalena; Stefanelli, Claudio; Minarini, Annaartículo
closedAccessaccesoRestringido.pdf.jpg21-May-2012Synthesis and Antimitotic and Tubulin Interaction Profiles of Novel Pinacol Derivatives of PodophyllotoxinsAbad, Andrés; López-Pérez, José Luis; Olmo, Esther del; García-Fernández, Luis F.; Francesch, Andrés; Trigili, Chiara CSIC; Barasoain, Isabel CSIC ; Andreu, José Manuel CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; San Feliciano, Arturoartículo
closedAccessaccesoRestringido.pdf.jpg28-Feb-2013Synthesis and biological evaluation as microtubule-active agents of several tetrahydrofuran and spiroacetal derivativesCarda, Miguel; Murga, Juan; Paños, Julián; Angulo-Pachón, C.A.; García-Pla, Jorge; Díaz-Oltra, Santiago; Marco, J. Alberto; Trigili, Chiara CSIC; Redondo-Horcajo, Mariano CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Barasoain, Isabel CSIC artículo
closedAccessaccesoRestringido.pdf.jpgFeb-2013Synthesis and Biological Evaluation of α-Tubulin-Binding Pironetin Analogues with Enhanced LipophilicityCarda, Miguel; Murga, Juan; Díaz-Oltra, Santiago; García-Pla, Jorge; Paños, Julián; Falomir, Eva; Trigili, Chiara CSIC; Díaz, José Fernando CSIC ORCID ; Barasoain, Isabel CSIC ; Marco, J. Albertoartículo
openAccessMatesanz et al_2014 _Bioorganic Medicinal Chemistry.pdf.jpg19-Jun-2014Taxanes with high potency inducing tubulin assembly overcome tumoural cell resistancesMatesanz, Ruth CSIC ; Trigili, Chiara CSIC; Rodríguez-Salarichs, Javier; Pera, Benet CSIC; Jiménez-Barbero, Jesús CSIC ORCID; Canales, Ángeles CSIC ORCID; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg1-Jun-2011Zampanolida, un novedoso agente estabilizador de microtubulos quew se une covalentemente al sitio de paclitaxelField, Jessica J.; Pera, Benet CSIC; Canales, Ángeles CSIC ORCID; Zuwerra, D.; Trigili, Chiara CSIC; Kanakkanthara, Arun; Wakefield, St. John; Singh, A. Jonathan; Jiménez-Barbero, Jesús CSIC ORCID; Northcote, Peter; Miller, J.; López, Juan Antonio; Hamel, Ernest; Barasoain, Isabel CSIC ; Altmann, Karl-Heinz; Díaz, José Fernando CSIC ORCID póster de congreso
openAccessField et al 2012_Chemistry and Biology.pdf.jpg22-Jun-2012Zampanolide, a potent new microtubule stabilizing agent, covalently reacts with the taxane luminal site in both tubulin alpha-beta-heterodimers and microtubulesField, Jessica J.; Pera, Benet CSIC; Calvo, Enrique; Canales, Ángeles CSIC ORCID; Zurwerra, Didier; Trigili, Chiara CSIC; Rodríguez-Salarichs, Javier; Matesanz, Ruth CSIC ; Kanakkanthara, Arun; Wakefield, St. John; Singh, A. Jonathan; Jiménez-Barbero, Jesús CSIC ORCID; Northcote, Peter; Miller, John H.; López, Juan Antonio; Hamel, Ernest; Barasoain, Isabel CSIC ; Altmann, Karl-Heinz; Díaz, José Fernando CSIC ORCID artículo