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openAccess1-s2.0-S2213231721002111-main.pdf.jpgsep-2021Acid ceramidase improves mitochondrial function and oxidative stress in Niemann-Pick type C disease by repressing STARD1 expression and mitochondrial cholesterol accumulationTorres, Sandra CSIC ORCID; Solsona-Vilarrasa, Estel CSIC ORCID; Nuñez, Susana CSIC; Matías, Nuria CSIC; Insausti, Naroa CSIC ORCID; Castro, Fernanda; Casasempere, Mireia; Fabriàs, Gemma CSIC ORCID ; Casas, Josefina CSIC ORCID ; Enrich, Carlos; Fernández-Checa, José C. CSIC ORCID; García-Ruiz, Carmen CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpgnov-2014ASMase regulates autophagy and lysosomal membrane permeabilization and its inhibition prevents early stage non-alcoholic steatohepatitisFucho, Raquel CSIC ORCID; Martínez, Laura CSIC; Baulies, Anna CSIC ORCID; Torres, Sandra CSIC ORCID; Tarrats, Núria CSIC; Fernández, Anna; Ribas, Vicent CSIC ORCID; Astudillo, Alma M. CSIC ORCID; Balsinde, Jesús CSIC ORCID ; Fernández-Checa, José C. CSIC ORCID; García-Ruiz, Carmen CSIC ORCID artículo
openAccessCholesterolenrichme_Solsona.pdf.jpgjun-2019Cholesterol enrichment in liver mitochondria impairs oxidative phosphorylation and disrupts the assembly of respiratory supercomplexesSolsona-Vilarrasa, Estel CSIC ORCID; Fucho, Raquel CSIC ORCID; Torres, Sandra CSIC ORCID; Nuñez, Susana CSIC; Nuño-Lámbarri, Natalia; Enrich, Carlos; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg9-nov-2018Cholesterol loading in liver mitochondria alters mitochondrial morphology, respiration and respiratory supercomplexes assemblySolsona-Vilarrasa, Estel CSIC ORCID; Fucho, Raquel CSIC ORCID; Torres, Sandra CSIC ORCID; Nuñez, Susana CSIC; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDcomunicación de congreso
closedAccessaccesoRestringido.pdf.jpg9-nov-2018Chronic alcohol feeding increases mitochondrial respiration in frg mice with humanized liverInsausti, Naroa CSIC ORCID; Solsona-Vilarrasa, Estel CSIC ORCID; Fucho, Raquel CSIC ORCID; Torres, Sandra CSIC ORCID; Alarcón-Vila, Cristina CSIC ORCID; Nuñez, Susana CSIC; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDpóster de congreso
openAccess1-s2.0-S2213231722000039-main.pdf.jpgabr-2022Corrigendum to “Acid ceramidase improves mitochondrial function and oxidative stress in Niemann-Pick type C disease by repressing STARD1 expression and mitochondrial cholesterol accumulation” [Redox Biol. 2021 45 102052]Torres, Sandra CSIC ORCID; Solsona-Vilarrasa, Estel CSIC ORCID; Nuñez, Susana CSIC; Matías, Nuria CSIC; Insausti, Naroa CSIC ORCID; Castro, Fernanda; Casasempere, Mireia; Fabriàs, Gemma CSIC ORCID ; Casas, Josefina CSIC ORCID ; Enrich, Carlos; Fernández-Checa, José C. CSIC ORCID; García-Ruiz, Carmen CSIC ORCID corrigenda
openAccess1-s2.0-S2213231722003688-main.pdf.jpgfeb-2023Dietary and genetic disruption of hepatic methionine metabolism induce acid sphingomyelinase to promote steatohepatitisAlarcón-Vila, Cristina CSIC ORCID; Insausti, Naroa CSIC ORCID; Torres, Sandra CSIC ORCID; Segalés, Paula CSIC; Conde de la Rosa, Laura CSIC ORCID ; Nuñez, Susana CSIC; Fucho, Raquel CSIC ORCID; Fernández-Checa, José C. CSIC ORCID; García-Ruiz, Carmen CSIC ORCID artículo
openAccessEndoplasmic Reticulum_Torres.pdf.jpgago-2019Endoplasmic Reticulum Stress-Induced Upregulation of STARD1 Promotes Acetaminophen-Induced Acute Liver FailureTorres, Sandra CSIC ORCID; Baulies, Anna CSIC ORCID; Insausti, Naroa CSIC ORCID; Alarcón-Vila, Cristina CSIC ORCID; Fucho, Raquel CSIC ORCID; Solsona-Vilarrasa, Estel CSIC ORCID; Nuñez, Susana CSIC; Robles, David CSIC; Ribas, Vicent CSIC ORCID; Wakefield, Leslie; Grompe, Markus; Lucena, M. Isabel; Andrade, Raúl J.; Win, Sanda; Aung, Tin; Kaplowitz, Neil; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg10-abr-2019FRI-098-Targeting cholesterol with atorvastatin protects against valproic acid-induced sensitization to acetaminophen hepatotoxicityTorres, Sandra CSIC ORCID; Nuñez, Susana CSIC; Insausti, Naroa CSIC ORCID; Solsona-Vilarrasa, Estel CSIC ORCID; Ribas, Vicent CSIC ORCID; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDpóster de congreso
openAccessHernandez S. GDF11 restricts aberrant lipogenesis and changes in mitocho....pdf.jpgmay-2021GDF11 restricts aberrant lipogenesis and changes in mitochondrial structure and function in human hepatocellular carcinoma cellsHernández-Rizo, Sharik; Simoni-Nieves, Arturo; Gerardo-Ramírez, Montserrat; Torres, Sandra CSIC ORCID; Fucho, Raquel CSIC ORCID; Gonzalez, Jonathan; Castellanos‐Tapia, Lyssia; Hernández‐Pando, Rogelio; Tejero‐Barrera, Elizabeth; Bucio, Leticia; Souza, Verónica; Miranda‐Labra, Roxana; Fernández-Checa, José C. CSIC ORCID; Marquardt, Jens U.; Gómez-Quiroz, Luís Enrique; García-Ruiz, Carmen CSIC ORCID ; Gutiérrez-Ruiz, María Concepciónartículo
openAccess18-mar-2022GST-Perfringolysin O production for the localization and quantification of membrane cholesterol in human and mouse brain and liverGoicoechea, Leire CSIC ORCID; Arenas, Fabian CSIC ORCID; Castro, Fernanda; Nuñez, Susana CSIC; Torres, Sandra CSIC ORCID; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpgago-2023HILPDA, a new player in NASH-driven HCC, links hypoxia signaling with ceramide synthesisFernández-Checa, José C. CSIC ORCID; Torres, Sandra CSIC ORCID; Garcia-Ruiz, Carmen editorial
openAccess2022Hypoxia signaling and cholesterol/steroidogenic acute regulatory protein 1 axis: interplay and role in alcohol and non-alcohol-related liver diseasesTorres, Sandra CSIC ORCID; Fernández-Checa, José C. CSIC ORCID; García-Ruiz, Carmen CSIC ORCID artículo de revisión
openAccessabr-2023Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosisTorres, Sandra CSIC ORCID; Ortiz, Cristina ; Bachtler, Nadine; Gu, Wenyi; Grünewald, Leon D.; Kraus, Nico; Schierwagen, Robert; Hieber, Christoph; Meier, Caroline; Tyc, Olaf; Brol, Maximilian Joseph; Uschner, Frank Erhard; Nijmeijer, Bart; Welsch, Christoph; Berres, Marie-Luise; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCID; Trautwein, Christian; Vogl, Thomas J.; Zeuzem, Stefan; Trebicka, Jonel; Klein, Sabineartículo
closedAccessaccesoRestringido.pdf.jpg27-ene-2022Janus kinase 2 inhibition by Pacritinib is a potential therapeutic target for liver fibrosis and portal hypertensionTorres, Sandra CSIC ORCIDcomunicación de congreso
openAccessLysosomal_Torres.pdf.jpg30-nov-2017Lysosomal and mitochondrial liaisons in niemann-pick diseaseTorres, Sandra CSIC ORCID; Balboa, Elisa; Zanlungo, Silvana; Enrich, Carlos; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDartículo
embargoedAccess2023Mitochondria and AlcoholTorres, Sandra CSIC ORCID; Segalés, Paula CSIC; Conde de la Rosa, Laura CSIC ORCID ; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDcapítulo de libro
openAccess27-abr-2022Mitochondria and the NLRP3 Inflammasome in Alcoholic and Nonalcoholic SteatohepatitisTorres, Sandra CSIC ORCID; Segalés, Paula CSIC; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDartículo
openAccess7-nov-2019Mitochondrial Cholesterol in Alzheimer's Disease and Niemann–Pick Type C DiseaseTorres, Sandra CSIC ORCID; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDartículo
may-2023Mitochondrial cholesterol: Metabolism and impact on redox biology and diseaseGoicoechea, Leire CSIC ORCID; Torres, Sandra CSIC ORCID; García-Ruiz, Carmen CSIC ORCID ; Fernández-Checa, José C. CSIC ORCIDartículo