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openAccess2015A Leishmania-specific hypothetical protein expressed in both promastigote and amastigote stages of Leishmania infantum employed for the serodiagnosis of, and as a vaccine candidate against, visceral leishmaniasisMartins, Vivian T.; Duarte, Mariana C.; Chávez-Fumagalli, Miguel A.; Menezes-Souza, Daniel; Coelho, C.; Magalhäes-Soares, Danielle F. de; Fernandes, Ana Paula; Soto, Manuel CSIC ORCID; Tavares, Carlos A. P.; Coelho, Eduardo A. F.artículo
openAccessRibeiroT_AnOptimized_Nanoparticle.pdf.jpg19-Nov-2014An optimized nanoparticle delivery system based on chitosan and chondroitin sulfate molecules reduces the toxicity of amphotericin B and is effective in treating tegumentary leishmaniasisRibeiro, Tatiana G; Soto, Manuel CSIC ORCID; Chávez-Fumagalli, Miguel A.artículo
openAccessSotoM_AnalysisOfTheAntigenic.pdf.jpg5-Apr-2018Analysis of the antigenic and prophylactic properties of the Leishmania translation initiation factors eIF2 and eIF2B in natural and experimental leishmaniasisGarde, Esther CSIC ORCID; Ramírez, Laura CSIC ORCID; Corvo, Laura CSIC ORCID; Solana, José Carlos; Requena, José María CSIC ORCID ; Soto, Manuel CSIC ORCIDartículo
openAccessM_Soto_Plos_One.pdf.jpg2013Antigenicity and Protective Efficacy of a Leishmania Amastigote-specific Protein, Member of the Super-oxygenase Family, against Visceral LeishmaniasisMartins, Vivian T.; Chávez-Fumagalli, Miguel A.; Costa, Lourena E.; Martins, Adriana M.C.C.; Lage, Paula S.; Lage, Mariana G. Duarte; Valadares, Diogo G.; Mgalhaes, Ruben D. M; Riberio, Tatiana G.; Nagem, Ronaldo A. P.; Warderson, D. Darocha; Williams, C. B. Régis; Soto, Manuel CSIC ORCID; Coelho, Eduardo A. F.; Fernandes, Ana Paula; Tavares, Carlos A. P.artículo
openAccessSoto Manuel Antigenicity.pdf.jpg14-Sep-2015Antigenicity, Immunogenicity and Protective Efficacy of Three Proteins Expressed in the Promastigote and Amastigote Stages of Leishmania infantum against Visceral LeishmaniasisTamietti Martins, Vivian; Soto, Manuel CSIC ORCID; Ferranz Coelho, Eduardo Antonioartículo
openAccessSoto Manuel Antileishmanial activity.pdf.jpg7-Sep-2015Antileishmanial activity and evaluation of the mechanism of action of strychnobiflavone flavonoid isolated from Strychnos pseudoquina against Leishmania infantumLage, Paula S.; Soto, Manuel CSIC ORCID; Coelho, Eduardo A. F.artículo
openAccessMSoto_BiochemJ_617.pdf.jpg9-Feb-2004Cell-cycle-dependent translation of histone mRNAs is the key control point for regulation of histone biosynthesis in Leishmania infantumSoto, Manuel CSIC ORCID; Iborra, Salvador; Quijada, Luis CSIC; Folgueira Fernández, Cristina CSIC; Alonso, Carlos CSIC; Requena, José María CSIC ORCID artículo
openAccessSoto M Coadministration.pdf.jpg8-May-2015Coadministration of the Three Antigenic Leishmania infantum Poly (A) Binding Proteins as a DNA Vaccine Induces Protection against Leishmania major Infection in BALB/c MiceSoto, Manuel CSIC ORCID; Corvo, Laura CSIC ORCID; Garde, Esther CSIC ORCID; Ramírez, Laura CSIC ORCID; Bonay, Pedro CSIC; Alonso, Carlos CSIC; Iborra, Salvadorartículo
openAccess1756-3305-7-3.pdf.jpg2-Jan-2014Cross-protective effect of a combined L5 plus L3 Leishmania major ribosomal protein based vaccine combined with a Th1 adjuvant in murine cutaneous and visceral leishmaniasisRamírez, Laura CSIC ORCID; Corvo, Laura CSIC ORCID; Duarte, Mariana C.; Chávez-Fumagalli, Miguel A.; Valadares, Diogo G.; Santos, Diego M.; Oliveira, Camila I. de; Escutia, Marta R.; Alonso, Carlos CSIC; Bonay, Pedro CSIC; Tavares, Carlos A. P.; Coelho, Eduardo A. F.; Soto, Manuel CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg2013Detection and chronology of parasitic kinetoplast DNA presence in hair of experimental Leishmania major infected BALB/c mice by Real Time PCRIniesta, Virginia; Belinchón-Lorenzo, Silvia; Soto, Manuel CSIC ORCID; Muñoz-Madrid, Rubén; Monroy, Isabel; Baz, Victoria; Gómez-Luque, Adela; Parejo, Juan Carlos; Alonso, Carlos CSIC; Gómez Nieto, Luis Carlos; Fernández-Cotrina, Javierartículo
closedAccessaccesoRestringido.pdf.jpg2013Detection of Leishmania infantum kinetoplast minicircle DNA by Real Time PCR in hair of dogs with leishmaniosisBelinchón-Lorenzo, Silvia; Iniesta, Virginia; Parejo, Juan Carlos; Fernández-Cotrina, Jesús; Muñoz-Madrid, Rubén; Soto, Manuel CSIC ORCID; Alonso, Carlos CSIC; Gómez Nieto, Luis Carlosartículo
openAccessPedro_Bonay_Differential.pdf.jpg31-Jul-2012Differential trypanocidal activity of novel macrolide antibiotics; correlation to genetic lineageAquilino, Carolina; González Rubio, María Luisa; Seco, Elena María; Escudero, Leticia CSIC; Corvo, Laura CSIC ORCID; Soto, Manuel CSIC ORCID; Fresno, Manuel CSIC ORCID ; Malpartida, Francisco; Bonay, Pedro CSICartículo
closedAccessaccesoRestringido.pdf.jpg2011DNA vaccination with KMP11 and Lutzomyia longipalpis salivary protein protects hamsters against visceral leishmaniasisSilva, Robson A. A. da; Tavares, Natália M.; Costa, Dirceu; Pitombo, Maiana; Barbosa, Larissa; Fukutani, Kyioshi; Miranda, José C.; Oliveira, Camila I. de; Valenzuela, Jesus G.; Barral, Aldina; Soto, Manuel CSIC ORCID; Barral-Netto, Manoel; Brodskyn, Cláudiaartículo
openAccessSoto M Evaluation of Adjuvant.pdf.jpg3-Apr-2015Evaluation of adjuvant activity of fractions derived from Agaricus blazei, when in association with the recombinant LiHyp1 protein, to protect against visceral leishmaniasisJesús Pererir, Nathália C. de; Soto, Manuel CSIC ORCID; Coelho, Eduardo A. F.artículo
closedAccessaccesoRestringido.pdf.jpg2013Evaluation of immune responses and analysis of the effect of vaccination of the Leishmania major recombinant ribosomal proteins L3 or L5 in two different murine models of cutaneous leishmaniasisRamírez, Laura CSIC ORCID; Santos, Diego M.; Souza, Ana P.; Coelho, Eduardo A. F.; Barral, Aldina; Alonso, Carlos CSIC; Escutia, Marta R.; Bonay, Pedro CSIC; Oliveira, Camila I. de; Soto, Manuel CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg2011Evaluation of parasitological and immunological parameters of Leishmania chagasi infection in BALB/c mice using different doses and routes of inoculation of parasitesOliveira, Dulcilene M.; Costa, Mariana A. F.; Chávez-Fumagalli, Miguel A.; Valadares, Diogo G.; Duarte, Mariana C.; Costa, Lourena E.; Martins, Vivian T.; Gomes, Rosângela F.; Melo, Maria N.; Soto, Manuel CSIC ORCID; Tavares, Carlos A. P.; Coelho, Eduardo A. F.artículo
closedAccessaccesoRestringido.pdf.jpg2013Experimental model for reproduction of canine visceral leishmaniosis by Leishmania infantumFernández-Cotrina, Jesús; Iniesta, Virginia; Belinchón-Lorenzo, Silvia; Muñoz-Madrid, Rubén; Serrano, Francisco Javier; Parejo, Juan Carlos; Gómez-Gordo, L.; Soto, Manuel CSIC ORCID; Alonso, Carlos CSIC; Gómez Nieto, Luis Carlosartículo
closedAccessaccesoRestringido.pdf.jpg31-Aug-2011H-ras and N-ras are dispensable for T-cell development and activation but critical for protective Th1 immunityIborra, Salvador; Soto, Manuel CSIC ORCID; Castellano, Esther; Alarcón, Balbino CSIC ORCID; Alonso, Carlos CSIC; Santos de Dios, Eugenio CSIC ORCID CVN artículo
closedAccessaccesoRestringido.pdf.jpg2011Identification and functional characterization of a poly(A)-binding protein from Leishmania infantum (LiPABP)Guerra, Natalia; Vega-Sendino, María CSIC; Pérez-Morgado, M. Isabel; Ramos, Edurne; Soto, Manuel CSIC ORCID; González, Víctor Manuel; Martín, M. Elenaartículo
openAccessCoelhoE_IdentificationofDifferentiallyExpressedProteins.pdf.jpg4-Apr-2014Identification of Differentially Expressed Proteins from Leishmania amazonensis Associated with the Loss of Virulence of the ParasitesMagalhaes, Rubens D:M.; Soto, Manuel CSIC ORCID; Coelho, Eduardo A. F.artículo