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openAccesss41467-023-36754-z.pdf.jpg28-feb-2023Engineering potent live attenuated coronavirus vaccines by targeted inactivation of the immune evasive viral deubiquitinaseMyeni, Sebenzile K.; Bredenbeek, Peter J.; Knaap, Robert C.; Dalebout, Tim J.; Torres Morales, Shessy; Sidorov, Igor A.; Linger, Marissa E.; Oreshkova, Nadia; van Zanen-Gerhardt, Sophie; Zander, Serge A. L.; Enjuanes Sánchez, Luis CSIC ORCID ; Solá Gurpegui, Isabel CSIC ORCID ; Snijder, Eric J.; Kikkert, Marjoleinartículo
openAccessAAC.02566-20.pdf.jpg17-jun-2021Structural Insights into the Mechanisms of Action of Functionally Distinct Classes of Chikungunya Virus Nonstructural Protein 1 InhibitorsKovacikova, Kristina; Gorostiola González, Marina; Jones, Rhian; Reguera, Juan; Gigante, Alba CSIC ORCID; Peréz-Pérez, María-Jesús CSIC ORCID ; Pürstinger, Gerhard; Moesslacher, Julia; Langer, Thierry; Jeong,Lak Shin; Delang, Leen; Neyts, Johan; Snijder, Eric J.; van Westen, Gerard J. P.; van Hemerta, Martijn J.artículo
closedAccessaccesoRestringido.pdf.jpg9-jun-2019The deubiquitinating activity of Middle East respiratory syndrome coronavirus papain-like protease contributes to innate immune evasion and enhances viral virulenceKnaap, Robert C.; Fernandez-Delgado, Raúl ; Dalebout, Tim J.; Oreshkova, Nadia; Bredenbeek, Peter J.; Enjuanes Sánchez, Luis CSIC ORCID ; Solá Gurpegui, Isabel CSIC ORCID ; Snijder, Eric J.; Kikkert, Marjoleinpóster de congreso
openAccessThe deubiquitinating activity_Knaap.pdf.jpg29-ago-2019The deubiquitinating activity of Middle East respiratory syndrome coronavirus papain-like protease delays the innate immune response and enhances virulence in a mouse modelKnaap, Robert C.; Fernandez-Delgado, Raúl ; Dalebout, Tim J.; Oreshkova, Nadia; Bredenbeek, Peter J.; Enjuanes Sánchez, Luis CSIC ORCID ; Solá Gurpegui, Isabel CSIC ORCID ; Snijder, Eric J.; Kikkert, Marjoleinartículo
openAccesssrep31819.pdf.jpg22-ago-2016The viral capping enzyme nsP1: a novel target for the inhibition of chikungunya virus infectionDelang, L.; Li, C.; Tas, A.; Quérat, G.; Albulescu, I. C.; De Burghgraeve, T.; Segura Guerrero, N. A.; Gigante, Alba CSIC ORCID; Piorkowski, G.; Decroly, E.; Jochmans, D.; Canard, B.; Snijder, Eric J.; Peréz-Pérez, María-Jesús CSIC ORCID ; Hemert, M. J. van; Coutard, B.; Leyssen, P.; Neyts, Johanartículo