Rights | Preview | Issue Date | Title | Author(s) | Type |
closedAccess |  | 2017 | Amiloride, an old diuretic drug, is a potential therapeutic agent for multiple myeloma | Rojas, Elizabeta A. CSIC ORCID; Corchete, Luis A.; San-Segundo, Laura; Martínez-Blanch, Juan F.; Codoñer, Francisco M.; Paíno, Teresa CSIC ORCID; Puig, Noemi; García-Sanz, Ramón; Mateos, Maria Victoria; Ocio, Enrique M. CSIC ORCID ; Misiewicz-Krzeminska, Irena; Gutiérrez, Norma Carmen | artículo |
openAccess |  | 2017 | C3G promotes a selective release of angiogenic factors from activated mouse platelets to regulate angiogenesis and tumor metastasis | Martín-Granado, Víctor; Ortiz-Rivero, Sara CSIC ORCID; Carmona, Rita; Gutiérrez-Herrero, Sara; Barrera, Mario; San-Segundo, Laura; Sequera, Celia; Perdiguero, Pedro; Lozano, Francisco S.; Martin-Herrero, Francisco; González-Porras, José R.; Muñoz-Chápuli, Ramón; Porras, Almudena; Guerrero Arroyo, María del Carmen CSIC ORCID | artículo |
openAccess |  | 2012 | CD20 positive cells are undetectable in the majority of multiple myeloma cell lines and are not associated with a cancer stem cell phenotype | Paíno, Teresa CSIC ORCID; Ocio, Enrique M. CSIC ORCID ; Paiva, Bruno; San-Segundo, Laura; Garayoa, Mercedes CSIC ORCID ; Gutiérrez, Norma Carmen; Sarasquete, María Eugenia; Pandiella, Atanasio CSIC ORCID CVN ; Orfao, Alberto CSIC ORCID ; San Miguel, Jesús F. CSIC ORCID | artículo |
closedAccess |  | 2018 | Changes in the gene expression profile of multiple myeloma cell line in response to immunomodulatory (IMIDs) drugs: MYB gen target | Fernández-Lázaro, Diego CSIC ORCID; Fernández-Lázaro, César Ignacio; San-Segundo, Laura; Ocio, Enrique M. CSIC ORCID | comunicación de congreso |
| | 2022 | Chloroquine-Induced DNA damage synergizes with nonhomologous end joining inhibition to cause ovarian cancer cell cytotoxicity | Ovejero-Sánchez, María; Rubio-Heras, Jorge; Vicente de la Peña, María del Carmen; San-Segundo, Laura; Pérez-Losada, J. CSIC ORCID ; González-Sarmiento, Rogelio CSIC ORCID CVN ; Herrero, Ana B. CSIC ORCID | artículo |
openAccess |  | 2020 | CRISPR/Cas9-generated models uncover therapeutic vulnerabilities of del(11q) CLL cells to dual BCR and PARP inhibition | Quijada-Álamo, Miguel; Hernández-Sánchez, María; Alonso-Pérez, Verónica CSIC ORCID; Rodríguez-Vicente, Ana Eugenia; García-Tuñón, Ignacio CSIC ORCID; Martín-Izquierdo, Marta; Hernandez-Sánchez, Jesus M.; Herrero, Ana B. CSIC ORCID; Bastida, José María; San-Segundo, Laura; Gruber, Michaela; García, Juan L. CSIC ORCID ; Yin, Shanye; Hacken, Elisa ten; Benito, Rocío; Ordóñez, José Luis CSIC ORCID; Wu, Catherine J.; Hernández, Jesús M. CSIC ORCID | artículo |
openAccess |  | 1-May-2010 | In vitro and in vivo rationale for the triple combination of panobinostat (LBH589) and dexamethasone with either bortezomib or lenalidomide in multiple myeloma | Ocio, Enrique M. CSIC ORCID ; Vilanova, David; Maiso, Patricia; Crusoe, Edvan; Fernández-Lázaro, Diego CSIC ORCID; Garayoa, Mercedes CSIC ORCID ; San-Segundo, Laura; Hernández, Mª Teresa; San Miguel, Jesús F. CSIC ORCID | artículo |
closedAccess |  | 2015 | In vivo murine model of acquired resistance in myeloma reveals differential mechanisms for lenalidomide and pomalidomide in combination with dexamethasone | Ocio, Enrique M. CSIC ORCID ; Fernández-Lázaro, Diego CSIC ORCID; San-Segundo, Laura; López-Corral, L.; Corchete, Luis A.; Gutiérrez, Norma Carmen; Garayoa, Mercedes CSIC ORCID ; Paíno, Teresa CSIC ORCID; García-Gómez, Antonio; Delgado, Manuel; Montero, Juan Carlos CSIC ORCID; Díaz-Rodríguez, Elena CSIC ORCID CVN; Mateos, Maria Victoria; Pandiella, Atanasio CSIC ORCID CVN ; San Miguel, Jesús F. CSIC ORCID | artículo |
closedAccess |  | 2015 | PD-L1/PD-1 presence in the tumor microenvironment and activity of PD-1 blockade in multiple myeloma | Paiva, Bruno; Puig, Noemi; Ocio, Enrique M. CSIC ORCID ; San-Segundo, Laura; Escalante, Ricardo CSIC ORCID ; San Miguel, Jesús F. CSIC ORCID; Melero, Ignacio | artículo |
closedAccess |  | 2015 | Phenotypic identification of subclones in multiple myeloma with different chemoresistant, cytogenetic and clonogenic potential | Paíno, Teresa CSIC ORCID; Paiva, Bruno; Sayagués, José María CSIC ORCID ; Corchete, Luis A.; Bárcena, Paloma; Ocio, Enrique M. CSIC ORCID ; San-Segundo, Laura; Sarasquete, María Eugenia; García-Sanz, Ramón; Vidriales, Maria Belén; Paiva, Artur; Bladé, Joan; Lahuerta, Juan José; Orfao, Alberto CSIC ORCID ; Mateos, Maria Victoria; Gutiérrez, Norma Carmen; Hernández, Mª Teresa; San Miguel, Jesús F. CSIC ORCID | artículo |
openAccess |  | 2014 | Phenotypic, genomic and functional characterization reveals no differences between CD138++ and CD138low subpopulations in multiple myeloma cell lines | Paíno, Teresa CSIC ORCID; Sarasquete, María Eugenia; Paiva, Bruno; Krzemiński, Patryk; San-Segundo, Laura; Corchete, Luis A.; Redondo, Alba; Garayoa, Mercedes CSIC ORCID ; García-Sanz, Ramón; Gutiérrez, Norma Carmen; Ocio, Enrique M. CSIC ORCID ; San Miguel, Jesús F. CSIC ORCID | artículo |
openAccess |  | 2017 | Preclinical anti-myeloma activity of EDO-S101, a new bendamustine-derived molecule with added HDACi activity, through potent DNA damage induction and impairment of DNA repair | López-Iglesias, Ana-Alicia; Herrero, Ana B. CSIC ORCID; Chesi, Marta; San-Segundo, Laura; González-Méndez, Lorena; Hernández-García, Susana CSIC; Misiewicz-Krzeminska, Irena; Quwaider, Dalia; Martín-Sánchez, Montserrat; Primo, Daniel; Paíno, Teresa CSIC ORCID; Bergsagel, P. Leif; Mehrling, Thomas; González, Marcos CSIC ORCID ; San Miguel, Jesús F. CSIC ORCID; Mateos, Maria Victoria; Gutiérrez, Norma Carmen; Garayoa, Mercedes CSIC ORCID ; Ocio, Enrique M. CSIC ORCID | artículo |
openAccess |  | 2020 | Preclinical evaluation of the simultaneous inhibition of MCL-1 and BCL-2 with the combination of S63845 and venetoclax in multiple myeloma | Algarín, Esperanza M.; Díaz-Tejedor, Andrea; Mogollón, Pedro; Hernández-García, Susana CSIC; Corchete, Luis A.; San-Segundo, Laura; Martín-Sánchez, Montserrat; González-Méndez, Lorena; Schoumacher, Marie; Banquet, Sebastien; Kraus-Berthie, Laurence; Kloos, Ioana; Derreal, Alix; Halilovic, Ensar; Maacke, Heiko; Gutiérrez, Norma Carmen; Mateos, Maria Victoria; Paíno, Teresa CSIC ORCID; Garayoa, Mercedes CSIC ORCID ; Ocio, Enrique M. CSIC ORCID | carta al director |
openAccess |  | 24-Sep-2020 | Protein Translation Inhibition is Involved in the Activity of the Pan-PIM Kinase Inhibitor PIM447 in Combination with Pomalidomide-Dexamethasone in Multiple Myeloma | Paíno, Teresa CSIC ORCID; González-Méndez, Lorena; San-Segundo, Laura; Corchete, Luis A.; Hernández-García, Susana CSIC; Díaz-Tejedor, Andrea; Algarín, Esperanza M.; Mogollón, Pedro; Martín-Sánchez, Montserrat; Gutiérrez, Norma Carmen; Mateos, Maria Victoria; Garayoa, Mercedes CSIC ORCID ; Ocio, Enrique M. CSIC ORCID | artículo |
openAccess |  | 2021 | Stroma-Mediated Resistance to S63845 and Venetoclax through MCL-1 and BCL-2 Expression Changes Induced by miR-193b-3p and miR-21-5p Dysregulation in Multiple Myeloma | Algarín, Esperanza M.; Quwaider, Dalia; Campos-Laborie, Francisco J.; Díaz-Tejedor, Andrea; Mogollón, Pedro; Vuelta, Elena; Martín-Sánchez, Montserrat; San-Segundo, Laura; González-Méndez, Lorena; Gutiérrez, Norma Carmen; García-Sanz, Ramón; Paíno, Teresa CSIC ORCID; De Las Rivas, Javier ; Ocio, Enrique M. CSIC ORCID ; Garayoa, Mercedes CSIC ORCID | artículo |
openAccess |  | 2017 | Synergistic DNA-damaging effect in multiple myeloma with the combination of zalypsis, bor tezomib and dexamethasone | López-Iglesias, Ana-Alicia; González-Méndez, Lorena; San-Segundo, Laura; Herrero, Ana B. CSIC ORCID; Hernández-García, Susana CSIC; Martín-Sánchez, Montserrat; Gutiérrez, Norma Carmen; Paíno, Teresa CSIC ORCID; Avilés Marín, Pablo; Mateos, Maria Victoria; San Miguel, Jesús F. CSIC ORCID; Garayoa, Mercedes CSIC ORCID ; Ocio, Enrique M. CSIC ORCID | artículo |
openAccess |  | 2021 | Targeting aberrant DNA methylation in mesenchymal stromal cells as a treatment for myeloma bone disease | García-Gómez, Antonio; Li, Tianlu; Rodríguez-Ubreva, Javier; Ciudad, Laura CSIC ORCID; Català-Moll, Francesc; Godoy-Tena, Gerard; Martín-Sánchez, Montserrat; San-Segundo, Laura; Muntión, Sandra; Morales, Xabier; Ortiz-de-Solorzano, Carlos; Oyarzabal, Julen; San José-Enériz, Edurne; Esteller, M.; Agirre, Xavier; Prosper, Felipe; Garayoa, Mercedes CSIC ORCID ; Ballestar, Esteban | artículo |
openAccess |  | 2017 | The novel pan-PIM kinase inhibitor, PIM447, displays dual antimyeloma and bone-protective effects, and potently synergizes with current standards of care | Paíno, Teresa CSIC ORCID; García-Gómez, Antonio; González-Méndez, Lorena; San-Segundo, Laura; Hernández-García, Susana CSIC; López-Iglesias, Ana-Alicia; Algarín, Esperanza M.; Martín-Sánchez, Montserrat; Corbacho-González, David; Ortiz-de-Solorzano, Carlos; Corchete, Luis A.; Gutiérrez, Norma Carmen; Mateos, Maria Victoria; Garayoa, Mercedes CSIC ORCID ; Ocio, Enrique M. CSIC ORCID | artículo |
openAccess |  | 2015 | The PARP inhibitor olaparib enhances the sensitivity of Ewing sarcoma to trabectedin | Ordóñez, José Luis CSIC ORCID; Amaral, Ana Teresa CSIC; Herrero-Martín, David; García-Macías, Carmen CSIC ORCID; Sevillano, Victoria CSIC; San-Segundo, Laura; Fraile, Susana CSIC; Teodosio, Cristina; Tirado, Óscar M.; Mora, Jaume; Álava, Enrique de CSIC ORCID | artículo |
closedAccess |  | 2012 | Transcriptomic rationale for the synergy observed with dasatinib + bortezomib + dexamethasone in multiple myeloma | Queiroz Crusoe, Edvan de; Maiso, Patricia; Fernández-Lázaro, Diego CSIC ORCID; San-Segundo, Laura; Garayoa, Mercedes CSIC ORCID ; García-Gómez, Antonio; Gutiérrez, Norma Carmen; Delgado, Manuel; Colado, Enrique; Ocio, Enrique M. CSIC ORCID | artículo |