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Browsing by Author Sánchez-Murcia, Pedro A.

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closedAccessaccesoRestringido.pdf.jpg20172′-Deoxyribosyltransferase from Leishmania mexicana, an efficient biocatalyst for one-pot, one-step synthesis of nucleosides from poorly soluble purine basesCrespo, N.; Sánchez-Murcia, Pedro A. CSIC ORCID; Gago, Federico CSIC ORCID; Cejudo-Sanches, J.; Galmes, M. A.; Fernández-Lucas, J.; Mancheño, Jose M. CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg2018Characterization of an atypical, thermostable, organic solvent- and acid-tolerant 2′-deoxyribosyltransferase from Chroococcidiopsis thermalisArco, J. del; Sánchez-Murcia, Pedro A. CSIC ORCID; Mancheño, Jose M. CSIC ORCID; Gago, Federico CSIC ORCID; Fernández-Lucas, J.artículo
closedAccessaccesoRestringido.pdf.jpg2019Cold-induced aldimine bond cleavage by Tris in: Bacillus subtilis alanine racemaseBernardo-García, Noelia CSIC; Sánchez-Murcia, Pedro A. CSIC ORCID; Espaillat, Akbar; Martínez-Caballero, S.; Cava, Felipe CSIC ORCID; Hermoso, Juan A. CSIC ORCID; Gago, Federico CSIC ORCIDartículo
openAccessMJC-4.pdf.jpg2015Comparison of hydrocarbon-and lactam-bridged cyclic peptides as dimerization inhibitors of Leishmania infantum trypanothione reductaseSánchez-Murcia, Pedro A. CSIC ORCID; Ruiz-Santaquiteria, Marta CSIC ORCID; Toro, Miguel A.; Lucio, H. de; Jiménez, M. Angeles CSIC ORCID ; Gago, Federico CSIC ORCID; Jiménez-Ruiz, Antonio; Camarasa Rius, María José CSIC ORCID; Velázquez, Sonsoles CSIC ORCID CVNartículo
openAccessMJC-1.pdf.jpg2015Conservation of antiviral activity and improved selectivity in PMEO-DAPym upon pyrimidine to triazine scaffold hoppingCastro, Sonia de; Fernández-Cureses, Gloria CSIC; Andrei, G; Snoeck, R.; Sánchez-Murcia, Pedro A. CSIC ORCID; Korban, B.; Gago, Federico CSIC ORCID; Balzarini, Jan; Camarasa Rius, María José CSIC ORCIDartículo
openAccessacs.jmedchem.1c00206.pdf.jpg2021Efficient Dimerization Disruption of Leishmania infantum Trypanothione Reductase by Triazole-phenyl-thiazolesRevuelto, Alejandro; Lucio, Héctor de; García-Soriano, Juan Carlos; Sánchez-Murcia, Pedro A. CSIC ORCID; Gago, Federico CSIC ORCID; Jiménez-Ruiz, Antonio; Camarasa Rius, María José CSIC ORCID; Velázquez, Sonsoles CSIC ORCID CVNartículo
openAccessenantioselective_oxidation_benavente.pdf.jpg2015Enantioselective oxidation of galactitol 1-phosphate by galactitol-1-phosphate 5-dehydrogenase from Escherichia coliBenavente, Rocio CSIC; Esteban-Torres, María CSIC ORCID; Kohring, G. W.; Cortés Cabrera, Álvaro CSIC ORCID; Sánchez-Murcia, Pedro A. CSIC ORCID; Gago, Federico CSIC ORCID; Acebrón, Iván CSIC ORCID; Rivas, Blanca de las CSIC ORCID; Muñoz, Rosario CSIC ORCID ; Mancheño, Jose M. CSIC ORCIDartículo
openAccess734083.pdf.jpg18-Jul-2018Enzymatic synthesis of therapeutic nucleosides using a highly versatile purine nucleoside 2’-Deoxyribosyl transferase from Trypanosoma bruceiPérez, Elena; Sánchez-Murcia, Pedro A. CSIC ORCID; Jordaan, Justin; Blanco, María Dolores; Mancheño, Jose M. CSIC ORCID; Gago, Federico CSIC ORCID; Fernández-Lucas, J.artículo
openAccessaccesoRestringido.pdf.jpg2017First example of peptides targeting the dimer interface of Leishmania infantum trypanothione reductase with potent in vitro antileishmanial activity#Ruiz-Santaquiteria, Marta CSIC ORCID; Sánchez-Murcia, Pedro A. CSIC ORCID; Toro, Miguel A.; Lucio, H. de; Gutierrez, Kilian Jesús.; Castro, Sonia de; Carneiro, Filipa A. C.; Gago, Federico; Jiménez-Ruiz, Antonio; Camarasa Rius, María José CSIC ORCID; Velázquez, Sonsoles CSIC ORCID CVNartículo
openAccessFunctional_Rocha_Martin_Art2019.pdf.jpg31-Oct-2019Functional characterization and structural analysis of NADH oxidase mutants from Thermus thermophilus HB27: Role of residues 166, 174, and 194 in the catalytic properties and thermostabilityRocha-Martín, Javier CSIC ORCID ; Sánchez-Murcia, Pedro A. CSIC ORCID; López-Gallego, Fernando; Hidalgo, Aurelio CSIC ORCID; Berenguer, José CSIC ORCID; Guisán, José Manuel CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2019Identification of NEK3 and MOK as novel targets for lithiumBravo, Ana; de Lucio, H.; Sánchez-Murcia, Pedro A. CSIC ORCID; Jiménez-Ruiz, Antonio; Petrone, Paula M.; Gago, Federico; Cortés Cabrera, Álvaro CSIC ORCIDartículo
openAccessSV-EJMC 2017- preprint.pdf.jpg21-Sep-2017Improved proteolytic stability and potent activity against Leishmania infantum trypanothione reductase of α/β-peptide foldamers conjugated to cell-penetrating peptidesLucio, Héctor de; Gamo, Ana María CSIC; Ruiz-Santaquiteria, Marta CSIC ORCID; Castro, Sonia de; Sánchez-Murcia, Pedro A. CSIC ORCID; Toro, Miguel A.; Gutiérrez, Kilian Jesús; Gago, Federico CSIC ORCID; Jiménez- Ruiz, Antonio; Camarasa Rius, María José CSIC ORCID; Velázquez, Sonsoles CSIC ORCID CVNartículo
openAccessSciReport_2016_38094.pdf.jpg2016Modular Architecture and Unique Teichoic Acid Recognition Features of Choline-Binding Protein L (CbpL) Contributing to Pneumococcal PathogenesisGutiérrez-Fernández, Javier; Saleh, M.; Alcorlo, Martín CSIC ORCID; Gómez-Mejóa, A.; Pantoja-Uceda, D.; Treviño, Miguel A. CSIC ORCID; Vob, F.; Abdullah, M.R.; Bartual, Sergio G. CSIC; Seinen, J.; Sánchez-Murcia, Pedro A. CSIC ORCID; Gago, Federico CSIC ORCID; Bruix, M. CSIC ORCID; Hammerschmidt, Sven; Hermoso, Juan A. CSIC ORCIDartículo
openAccessACSMCL2020_RT-dimeriz-inhibs-3(revised-for publication).pdf.jpg2020Peptides mimicking the β7/β8 loop of HIV'1 reverse transcriptase p51 as “hotspot-targeted” dimerization inhibitorsSánchez-Murcia, Pedro A. CSIC ORCID; Castro, Sonia de; García-Aparicio, Carlos CSIC; Jiménez, M. Angeles CSIC ORCID ; Corona, A.; Tramontano, Enzo; Sluis-Cremer, N.; Menéndez-Arias, Luis CSIC ORCID ; Velázquez, Sonsoles CSIC ORCID CVN; Gago, Federico CSIC ORCID; Camarasa Rius, María José CSIC ORCIDartículo
closedAccess6-Jun-2013Probing the Dimerization Interface of Leishmania infantum Trypanothione Reductase with Site-Directed Mutagenesis and Short PeptidesToro, Miguel A.; Sánchez-Murcia, Pedro A. CSIC ORCID; Moreno, David; Ruiz-Santaquiteria, Marta CSIC ORCID; Fernando Alzate, Juan; Negri, Ana; Camarasa Rius, María José CSIC ORCID; Gago, Federico CSIC ORCID; Velázquez, Sonsoles CSIC ORCID CVN; Jiménez-Ruiz, Antonioartículo
openAccessaccesoRestringido.pdf.jpg2019Pyrrolopyrimidine vs imidazole-phenyl-thiazole scaffolds in nonpeptidic dimerization inhibitors of leishmania infantum trypanothione reductaseRevuelto, Alejandro; Ruiz-Santaquiteria, Marta CSIC ORCID; Lucio, Héctor de; Gamo, Ana; Carriles, Alejandra A.; Gutiérrez, Kilian Jesús; Sánchez-Murcia, Pedro A. CSIC ORCID; Gago, Federico CSIC ORCID; Camarasa Rius, María José CSIC ORCID; Jiménez-Ruiz, Antonio; Velázquez, Sonsoles CSIC ORCID CVNartículo
closedAccessaccesoRestringido.pdf.jpg2019Reaction mechanism of nucleoside 2′-deoxyribosyltransferases: Free-energy landscape supports an oxocarbenium ion as the reaction intermediateDel Arco, J.; Perona, A.; González, L.; Fernández-Lucas, J.; Gago, Federico CSIC ORCID; Sánchez-Murcia, Pedro A. CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg2016Structural bioinformatics in broad-spectrum racemases: A new path in antimicrobial researchBernardo-García, Noelia CSIC; Sánchez-Murcia, Pedro A. CSIC ORCID; Gago, Federico CSIC ORCID; Cava, Felipe CSIC ORCID; Hermoso, Juan A. CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg13-Dec-2016Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer CellsTrigili, Chiara CSIC; Barasoain, Isabel CSIC ; Sánchez-Murcia, Pedro A. CSIC ORCID; Bargsten, Katja; Redondo-Horcajo, Mariano CSIC ORCID ; Nogales, Aurora CSIC ORCID; Gardner, Nicola M.; Meyer, Arndt; Naylor, Guy J.; Gomez-Rubio, Elena; Gago, Federico CSIC ORCID; Steinmetz, Michel O.; Paterson, Ian; Prota, Andrea E.; Díaz, José Fernando CSIC ORCID artículo
openAccessgkx629.pdf.jpg2017Structure-based domain assignment in Leishmania infantum EndoG: Characterization of a pH-dependent regulatory switch and a C-Terminal extension that largely dictates DNA substrate preferencesOliva, C.; Sánchez-Murcia, Pedro A. CSIC ORCID; Rico, E.; Bravo, A.; Menéndez, Margarita CSIC ORCID; Gago, Federico CSIC ORCID; Jiménez-Ruiz, A.artículo