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Browsing by Author Sánchez-Fernández, Elena M.

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openAccessWO2023073005A1.pdf.jpg4-May-20235-Aminohexahydro-6,7,8-trihydroxy-3H-oxazolo[3,4-a]pyridin-3-one derivatives derivatives as TLR4 modulators for the treatment of immune diseasesGarcía Fernández, José Manuel CSIC ORCID; Ortiz-Mellet, Carmen; González-Cuesta, Manuel; Sánchez-Fernández, Elena M. CSIC ORCID; Chang, Ya-Jen; Lai, Alan Chuan-Yingsolicitud de patente
openAccessEP4174075A1.pdf.jpg3-May-20235-Aminohexahydro-6,7,8-trihydroxy-3H-oxazolo[3,4-a]pyridin-3-one derivatives derivatives as TLR4 modulators for the treatment of immune diseasesGarcía Fernández, José Manuel CSIC ORCID; Ortiz-Mellet, Carmen; González-Cuesta, Manuel; Sánchez-Fernández, Elena M. CSIC ORCID; Chang, Ya-Jen; Lai, Alan Chuan-Yingsolicitud de patente
openAccessfimmu-12-632132.pdf.jpg2021Anti-Inflammatory (M2) Response Is Induced by a sp2-Iminosugar Glycolipid Sulfoxide in Diabetic RetinopathyCano-Cano, Fátima; Alcalde-Estévez, Elena; Gómez-Jaramillo, Laura; Iturregi, Marta; Sánchez-Fernández, Elena M. CSIC ORCID; García Fernández, José Manuel CSIC ORCID; Ortiz Mellet, Carmen; Campos-Caro, Antonio CSIC ORCID; López-Tinoco, Cristina; Aguilar-Diosdado, Manuel; Valverde, Ángela M. CSIC ORCID ; Arroba, Ana I. CSIC ORCIDartículo
openAccessc5ra02627j.pdf.jpg2015Antileishmanial activity of sp2-iminosugar derivativesSánchez-Fernández, Elena M. CSIC ORCID; Gómez-Pérez, Veronica; García-Hernández, Raquel CSIC ORCID; García Fernández, José Manuel CSIC ORCID; Plata, Gabriela B.; Padrón, José M.; Ortiz-Mellet, Carmen; Catanys, Santiago; Gamarro, Franciscoartículo
openAccess2016Conformationally-Locked C-Glycosides: Tuning Aglycone Interactions for Optimal Cheperone Behaviour in Gaucher FibroblastsNavo, C.D.; Corzana, Francisco; Sánchez-Fernández, Elena M. CSIC ORCID; Busto, J.H.; Avenoza, A.; Namba, E.; Higaki, Katsumi; Ortiz-Mellet, Carmen; García Fernández, José Manuel CSIC ORCID; Peregrina, Jesús M.artículo
closedAccessaccesoRestringido.pdf.jpg2012Efficient Transfection of Hepatocytes Mediated by mRNA Complexed to Galactosylated CyclodextrinsSymens, Nathalie; Méndez-Ardoy, Alejandro CSIC ORCID; Díaz Moscoso, Alejandro CSIC ORCID ; Sánchez-Fernández, Elena M. CSIC ORCID; Remaut, Katrien; Demeester, Joseph; García Fernández, José Manuel CSIC ORCID; De Smedt, Stefaan; Rejman, Joannaartículo
openAccessJ. Med. Chem. Just accepted.pdf.jpg2017Fluorinated chaperone-ß-cyclodextrin formulations for ß-glucocerebrosidase activity enhancement in neuronopathic Gaucher diseaseGarcía Moreno, María Isabel; Mata, Mario de la CSIC ORCID; Sánchez-Fernández, Elena M. CSIC ORCID; Benito, Juan M. CSIC ORCID CVN ; Díaz-Quintana, Antonio; Fustero, Santos; Nanba, Eiji; Higaki, Katsumi; Sánchez-Alcázar, José Antonio CSIC ORCID ; García Fernández, José Manuel CSIC ORCID; Ortiz-Mellet, Carmenartículo
closedAccess16-Jul-2009Generalized Anomeric Effect in gem-Diamines: Stereoselective Synthesis of α-N-Linked Disaccharide MimicsSánchez-Fernández, Elena M. CSIC ORCID; Rísquez-Cuadro, Rocio; Aguilar Moncayo, Matilde; García Moreno, María Isabel; Ortiz-Mellet, Carmen; García Fernández, José Manuel CSIC ORCIDartículo
openAccessC6CC01564F.pdf.jpg2016Glycomimetic-based pharmacological chaperones for lysosomal storage disorders: lessons from Gaucher, GM1-gangliosidosis and Fabry diseasesSánchez-Fernández, Elena M. CSIC ORCID; García Fernández, José Manuel CSIC ORCID; Ortiz-Mellet, Carmenartículo
openAccessWO2011151493A1.pdf.jpg8-Dec-2011Iminosugar derivatives as alfa-glycosidase inhibitorsGarcía Fernández, José Manuel CSIC ORCID; Sánchez-Fernández, Elena M. CSIC ORCID; Ortiz-Mellet, Carmen; Rísquez-Cuadro, Rociosolicitud de patente
closedAccessaccesoRestringido.pdf.jpg24-Jun-2016Influence of the configurational pattern of sp2-iminosugar pseudo N-, S-, O- and C-glycosides on their glycoside inhibitory and antitumor propertiesSánchez-Fernández, Elena M. CSIC ORCID; Gonçalves-Pereira, Rita; Rísquez-Cuadro, Rocío; Plata, Gabriela B.; Padrón, José M.; García Fernández, José Manuel CSIC ORCID; Ortiz Mellet, Carmenartículo
openAccessjournal.pone.0076411.pdf.jpg2013New Castanospermine Glycoside Analogues Inhibit Breast Cancer Cell Proliferation and Induce Apoptosis without Affecting Normal CellsAllan, Ghada; Quadid-Ahidouch, H.; Sánchez-Fernández, Elena M. CSIC ORCID; Rísquez-Cuadro, Rocio; García Fernández, José Manuel CSIC ORCID; Ortiz-Mellet, Carmen; Ahidouch, Ahmedartículo
openAccess30-Jun-2019Polyfluoroalkyl Glycolipid Mimetics as Immunomodulatory AgentsSánchez-Fernández, Elena M. CSIC ORCID; García-Moreno, Mª Isabel; Arroba, Ana I. CSIC ORCID; Padrón, José M.; García-Hernández, Raquel CSIC ORCID; Gamarro, Francisco; García Fernández, José Manuel CSIC ORCID; Masgrau, Laura; Ortiz Mellet, Carmencomunicación de congreso
openAccessEur. J. Med. Chem. 2019, 169, 111-120 accepted.pdf.jpg2019sp 2 -Iminosugar glycolipids as inhibitors of lipopolysaccharide-mediated human dendritic cell activation in vitro and of acute inflammation in mice in vivoSchaeffer, Evelyne; Sánchez-Fernández, Elena M. CSIC ORCID; Gonçalves-Pereira, Rita; Flacher, Vincent; Lamon, Delphine; Duval, Monique; Fauny, J-D.; García Fernández, José Manuel CSIC ORCID; Ortiz-Mellet, Carmenartículo
closedAccessaccesoRestringido.pdf.jpg2012Sp 2-iminosugar O-, S-, and N-glycosides as conformational mimics of ¿-linked disaccharides; Implications for glycosidase inhibitionSánchez-Fernández, Elena M. CSIC ORCID; Rísquez-Cuadro, Rocio; Ortiz-Mellet, Carmen; García Fernández, José Manuel CSIC ORCID; Nieto, Pedro M. CSIC ORCID ; Angulo, Jesús CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpgDec-2017sp2-Iminosugar α-glucosidase inhibitor 1-C-octyl-2-oxa-3-oxocastanospermine specifically affected breast cancer cell migration through Stim1, β1-integrin, and FAK signaling pathwaysGueder, Nahla; Allan, Ghada; Telliez, Marie-Sophie; Hague, Frédéric; Fernandez, José M.; Sánchez-Fernández, Elena M. CSIC ORCID; Ortiz-Mellet, Carmen; Ahidouch, Ahmed; Ouadid-Ahidouch, Halimaartículo
closedAccessaccesoRestringido.pdf.jpg2014Synthesis of multibranched australine derivatives from reducing castanospermine analogues through the amadori rearrangement of gem -diamine intermediates: Selective inhibitors of β-glucosidaseSánchez-Fernández, Elena M. CSIC ORCID; Álvarez, Eleuterio CSIC ORCID ; Ortiz-Mellet, Carmen; García Fernández, José Manuel CSIC ORCIDartículo
closedAccess15-Jun-2010Synthesis of N-, S-, and C-glycoside castanospermine analogues with selective neutral α-glucosidase inhibitory activity as antitumour agentsSánchez-Fernández, Elena M. CSIC ORCID; Rísquez-Cuadro, Rocio; Chasseraud, Maud; Ahidouch, Ahmed; Ortiz-Mellet, Carmen; Ouadid-Ahidouch, Halima; García Fernández, José Manuel CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg2019Synthesis of polyfluoroalkyl sp2-iminosugar glycolipids and evaluation of their immunomodulatory properties towards anti-tumor, anti-leishmanial and anti-inflammatory therapiesSánchez-Fernández, Elena M. CSIC ORCID; García-Moreno, M. Isabel; Arroba, Ana I. CSIC ORCID; Aguilar-Diosdado, Manuel; Padrón, José M.; García-Hernández, Raquel CSIC ORCID; Gamarro, Francisco; Fustero, Santos; Sánchez-Aparicio, J.E.; Masgrau, Laura; García Fernández, José Manuel CSIC ORCID; Ortiz Mellet, Carmenartículo
openAccessmolecules-26-07501.pdf.jpg11-Dec-2021Synthesis of sp2 -Iminosugar Selenoglycolipids as Multitarget Drug Candidates with Antiproliferative, Leishmanicidal and Anti-Inflammatory PropertiesSánchez-Fernández, Elena M. CSIC ORCID; García-Hernández, Raquel CSIC ORCID; Gamarro, F.; Arroba, A. I.; Aguilar-Diosdado, Manuel; Padrón, José M.; García Fernández, José Manuel CSIC ORCID; Ortiz Mellet, Carmenartículo