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Browsing by Author Sánchez-Fernández, Elena M.

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openAccessc5ra02627j.pdf.jpg2015Antileishmanial activity of sp2-iminosugar derivativesSánchez-Fernández, Elena M. ; Gómez-Pérez, Veronica; García-Hernández, Raquel; García-Fernández, José Manuel; Plata, Gabriela B.; Padrón, José M.; Ortiz-Mellet, Carmen; Catanys, Santiago; Gamarro, Franciscoartículo
openAccess2016Conformationally-Locked C-Glycosides: Tuning Aglycone Interactions for Optimal Cheperone Behaviour in Gaucher FibroblastsNavo, C.D.; Corzana, F.; Sánchez-Fernández, Elena M. ; Busto, J.H.; Avenoza, A.; Namba, E.; Higaki, Katsumi; Ortiz-Mellet, Carmen; García-Fernández, José Manuel; Peregrina, J.M.artículo
closedAccessaccesoRestringido.pdf.jpg2012Efficient Transfection of Hepatocytes Mediated by mRNA Complexed to Galactosylated CyclodextrinsSymens, Nathalie; Méndez-Ardoy, Alejandro ; Díaz-Moscoso, Alejandro; Sánchez-Fernández, Elena M. ; Remaut, Katrien; Demeester, Joseph; García-Fernández, José Manuel; De Smedt, Stefaan; Rejman, Joannaartículo
openAccessJ. Med. Chem. Just accepted.pdf.jpg2017Fluorinated chaperone-ß-cyclodextrin formulations for ß-glucocerebrosidase activity enhancement in neuronopathic Gaucher diseaseGarcía Moreno, María Isabel; Mata, Mario de la ; Sánchez-Fernández, Elena M. ; Benito, Juan M. ; Díaz-Quintana, Antonio; Fustero, Santos; Nanba, Eiji; Higaki, Katsumi; Sánchez-Alcázar, José Antonio ; García-Fernández, José Manuel; Ortiz-Mellet, Carmenartículo
closedAccess16-Jul-2009Generalized Anomeric Effect in gem-Diamines: Stereoselective Synthesis of α-N-Linked Disaccharide MimicsSánchez-Fernández, Elena M. ; Rísquez-Cuadro, Rocio; Aguilar Moncayo, Matilde ; García Moreno, María Isabel; Ortiz-Mellet, Carmen; García-Fernández, José Manuelartículo
openAccessC6CC01564F.pdf.jpg2016Glycomimetic-based pharmacological chaperones for lysosomal storage disorders: lessons from Gaucher, GM1-gangliosidosis and Fabry diseasesSánchez-Fernández, Elena M. ; García-Fernández, José Manuel; Ortiz-Mellet, Carmenartículo
openAccessWO2011151493A1.pdf.jpg8-Dec-2011Iminosugar derivatives as alfa-glycosidase inhibitorsGarcía Fernández, José Manuel ; Sánchez-Fernández, Elena M. ; Ortiz-Mellet, Carmen; Rísquez-Cuadro, Rociosolicitud de patente
closedAccessaccesoRestringido.pdf.jpg24-Jun-2016Influence of the configurational pattern of sp2-iminosugar pseudo N-, S-, O- and C-glycosides on their glycoside inhibitory and antitumor propertiesSánchez-Fernández, Elena M. ; Gonçalves-Pereira, Rita; Rísquez-Cuadro, Rocío; Plata, Gabriela B.; Padrón, José M.; García Fernández, José Manuel ; Ortiz Mellet, Carmenartículo
openAccessjournal.pone.0076411.pdf.jpg2013New Castanospermine Glycoside Analogues Inhibit Breast Cancer Cell Proliferation and Induce Apoptosis without Affecting Normal CellsAllan, Ghada; Quadid-Ahidouch, H.; Sánchez-Fernández, Elena M. ; Rísquez-Cuadro, Rocio; García-Fernández, José Manuel; Ortiz-Mellet, Carmen; Ahidouch, Ahmedartículo
openAccess30-Jun-2019Polyfluoroalkyl Glycolipid Mimetics as Immunomodulatory AgentsSánchez-Fernández, Elena M. ; García-Moreno, Mª Isabel; Arroba, Ana Isabel; Padrón, José Manuel; García-Hernández, Raquel; Gamarro, Francisco; García Fernández, José Manuel ; Masgrau, Laura; Ortiz Mellet, Carmencomunicación de congreso
embargoedAccessEur. J. Med. Chem. 2019, 169, 111-120 accepted.pdf.jpg2019sp 2 -Iminosugar glycolipids as inhibitors of lipopolysaccharide-mediated human dendritic cell activation in vitro and of acute inflammation in mice in vivoSchaeffer, Evelyne; Sánchez-Fernández, Elena M. ; Gonçalves-Pereira, Rita; Flacher, Vincent; Lamon, Delphine; Duval, Monique; Fauny, J-D.; García-Fernández, José Manuel; Ortíz-Mellet, Carmenartículo
closedAccessaccesoRestringido.pdf.jpg2012Sp 2-iminosugar O-, S-, and N-glycosides as conformational mimics of ¿-linked disaccharides; Implications for glycosidase inhibitionSánchez-Fernández, Elena M. ; Rísquez-Cuadro, Rocio; Ortiz-Mellet, Carmen; García-Fernández, José Manuel; Nieto, Pedro M.  ; Angulo, Jesús artículo
closedAccessaccesoRestringido.pdf.jpgDec-2017sp2-Iminosugar α-glucosidase inhibitor 1-C-octyl-2-oxa-3-oxocastanospermine specifically affected breast cancer cell migration through Stim1, β1-integrin, and FAK signaling pathwaysGueder, Nahla; Allan, Ghada; Telliez, Marie-Sophie; Hague, Frédéric; Fernandez, José M.; Sánchez-Fernández, Elena M. ; Ortiz-Mellet, Carmen; Ahidouch, Ahmed; Ouadid-Ahidouch, Halimaartículo
closedAccessaccesoRestringido.pdf.jpg2014Synthesis of multibranched australine derivatives from reducing castanospermine analogues through the amadori rearrangement of gem -diamine intermediates: Selective inhibitors of β-glucosidaseSánchez-Fernández, Elena M. ; Álvarez, Eleuterio ; Ortiz-Mellet, Carmen; García-Fernández, José Manuelartículo
closedAccess15-Jun-2010Synthesis of N-, S-, and C-glycoside castanospermine analogues with selective neutral α-glucosidase inhibitory activity as antitumour agentsSánchez-Fernández, Elena M. ; Rísquez-Cuadro, Rocio; Chasseraud, Maud; Ahidouch, Ahmed; Ortiz-Mellet, Carmen; Ouadid-Ahidouch, Halima; García-Fernández, José Manuelartículo
closedAccessaccesoRestringido.pdf.jpg2019Synthesis of polyfluoroalkyl sp2-iminosugar glycolipids and evaluation of their immunomodulatory properties towards anti-tumor, anti-leishmanial and anti-inflammatory therapiesSánchez-Fernández, Elena M. ; García-Moreno, M. Isabel; Arroba, Ana I. ; Aguilar-Diosdado, Manuel; Padrón, José M.; García-Hernández, Raquel; Gamarro, Francisco; Fustero, Santos; Sánchez-Aparicio, J.E.; Masgrau, Laura; García Fernández, José Manuel ; Ortiz Mellet, Carmenartículo
openAccessc9sc06334j.pdf.jpg2020Synthesis, conformational analysis and in vivo assays of an anti-cancer vaccine that features an unnatural antigen based on an sp2-iminosugar fragmentBermejo, Iris A.; Navo, Claudio D.; Castro-López, Jorge; Guerreiro, Ana; Jiménez-Moreno, Ester; Sánchez-Fernández, Elena M. ; García-Martín, Fayna; Hinou, Hiroshi; Nishimura, Shin-Ichiro; García-Fernández, José M.; Ortiz-Mellet, Carmen; Avenoza, Alberto; Busto, Jesús H.; Bernardes, Gonçalo; Hurtado-Guerrero, Ramón; Peregrina, Jesús M.; Corzana, Franciscoartículo
openAccessFCT-S-17-01952.pdf.jpg2018The sp2-iminosugar glycolipid 1-dodecylsulfonyl-5N,6O-oxomethylidenenojirimycin (DSO2-ONJ) as selective anti-inflammatory agent by modulation of hemeoxygenase-1 in Bv.2 microglial cells and retinal explantsAlcalde-Estévez, Elena; Arroba, Ana I. ; Sánchez-Fernández, Elena M. ; Ortiz-Mellet, Carmen; García Fernández, José Manuel ; Masgrau, Laura; Valverde, Ángela M.artículo
openAccessthiol-ene_click_synthesis_pharmacological_evaluation_c-glycoside_sp2-iminosugar_glycolipids.pdf.jpg8-Aug-2019Thiol-ene "click" synthesis and pharmacological evaluation of c-glycoside sp2-iminosugar glycolipidsSánchez-Fernández, Elena M. ; García-Moreno, M. Isabel; García-Hernández, Raquel; Padrón, José M.; García Fernández, José Manuel ; Gamarro, Francisco; Ortiz Mellet, Carmenartículo
openAccessmolecules-24-02882.pdf.jpg2019Thiol-ene >click> synthesis and pharmacological evaluation of C-glycoside sp2-iminosugar glycolipidsSánchez-Fernández, Elena M. ; García-Moreno, M. Isabel; García-Hernández, Raquel; Padrón, José M.; García Fernández, José Manuel ; Gamarro, Francisco; Ortiz Mellet, Carmenartículo