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Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
openAccess | | 3-may-2023 | 5-Aminohexahydro-6,7,8-trihydroxy-3H-oxazolo[3,4-a]pyridin-3-one derivatives derivatives as TLR4 modulators for the treatment of immune diseases | García Fernández, José Manuel CSIC ORCID; Ortiz-Mellet, Carmen; González-Cuesta, Manuel; Sánchez-Fernández, Elena M. CSIC ORCID; Chang, Ya-Jen; Lai, Alan Chuan-Ying | solicitud de patente |
openAccess | | 4-may-2023 | 5-Aminohexahydro-6,7,8-trihydroxy-3H-oxazolo[3,4-a]pyridin-3-one derivatives derivatives as TLR4 modulators for the treatment of immune diseases | García Fernández, José Manuel CSIC ORCID; Ortiz-Mellet, Carmen; González-Cuesta, Manuel; Sánchez-Fernández, Elena M. CSIC ORCID; Chang, Ya-Jen; Lai, Alan Chuan-Ying | solicitud de patente |
openAccess | | 2021 | Anti-Inflammatory (M2) Response Is Induced by a sp2-Iminosugar Glycolipid Sulfoxide in Diabetic Retinopathy | Cano-Cano, Fátima; Alcalde-Estévez, Elena; Gómez-Jaramillo, Laura; Iturregi, Marta; Sánchez-Fernández, Elena M. CSIC ORCID; García Fernández, José Manuel CSIC ORCID; Ortiz Mellet, Carmen; Campos-Caro, Antonio CSIC ORCID; López-Tinoco, Cristina; Aguilar-Diosdado, Manuel; Valverde, Ángela M. CSIC ORCID ; Arroba, Ana I. CSIC ORCID | artículo |
openAccess | | 2015 | Antileishmanial activity of sp2-iminosugar derivatives | Sánchez-Fernández, Elena M. CSIC ORCID; Gómez-Pérez, Veronica; García-Hernández, Raquel CSIC ORCID; García Fernández, José Manuel CSIC ORCID; Plata, Gabriela B.; Padrón, José M.; Ortiz-Mellet, Carmen; Catanys, Santiago; Gamarro, Francisco | artículo |
openAccess | | 2016 | Conformationally-Locked C-Glycosides: Tuning Aglycone Interactions for Optimal Cheperone Behaviour in Gaucher Fibroblasts | Navo, C.D.; Corzana, Francisco; Sánchez-Fernández, Elena M. CSIC ORCID; Busto, J.H.; Avenoza, A.; Namba, E.; Higaki, Katsumi; Ortiz-Mellet, Carmen; García Fernández, José Manuel CSIC ORCID; Peregrina, Jesús M. | artículo |
closedAccess | | 2012 | Efficient Transfection of Hepatocytes Mediated by mRNA Complexed to Galactosylated Cyclodextrins | Symens, Nathalie; Méndez-Ardoy, Alejandro CSIC ORCID; Díaz Moscoso, Alejandro CSIC ORCID ; Sánchez-Fernández, Elena M. CSIC ORCID; Remaut, Katrien; Demeester, Joseph; García Fernández, José Manuel CSIC ORCID; De Smedt, Stefaan; Rejman, Joanna | artículo |
openAccess | | 2017 | Fluorinated chaperone-ß-cyclodextrin formulations for ß-glucocerebrosidase activity enhancement in neuronopathic Gaucher disease | García Moreno, María Isabel; Mata, Mario de la CSIC ORCID; Sánchez-Fernández, Elena M. CSIC ORCID; Benito, Juan M. CSIC ORCID CVN ; Díaz-Quintana, Antonio; Fustero, Santos; Nanba, Eiji; Higaki, Katsumi; Sánchez-Alcázar, José Antonio CSIC ORCID ; García Fernández, José Manuel CSIC ORCID; Ortiz-Mellet, Carmen | artículo |
closedAccess | | 16-jul-2009 | Generalized Anomeric Effect in gem-Diamines: Stereoselective Synthesis of α-N-Linked Disaccharide Mimics | Sánchez-Fernández, Elena M. CSIC ORCID; Rísquez-Cuadro, Rocio; Aguilar Moncayo, Matilde; García Moreno, María Isabel; Ortiz-Mellet, Carmen; García Fernández, José Manuel CSIC ORCID | artículo |
openAccess | | 2016 | Glycomimetic-based pharmacological chaperones for lysosomal storage disorders: lessons from Gaucher, GM1-gangliosidosis and Fabry diseases | Sánchez-Fernández, Elena M. CSIC ORCID; García Fernández, José Manuel CSIC ORCID; Ortiz-Mellet, Carmen | artículo |
openAccess | | 8-dic-2011 | Iminosugar derivatives as alfa-glycosidase inhibitors | García Fernández, José Manuel CSIC ORCID; Sánchez-Fernández, Elena M. CSIC ORCID; Ortiz-Mellet, Carmen; Rísquez-Cuadro, Rocio | solicitud de patente |
closedAccess | | 24-jun-2016 | Influence of the configurational pattern of sp2-iminosugar pseudo N-, S-, O- and C-glycosides on their glycoside inhibitory and antitumor properties | Sánchez-Fernández, Elena M. CSIC ORCID; Gonçalves-Pereira, Rita; Rísquez-Cuadro, Rocío; Plata, Gabriela B.; Padrón, José M.; García Fernández, José Manuel CSIC ORCID; Ortiz Mellet, Carmen | artículo |
openAccess | | 2013 | New Castanospermine Glycoside Analogues Inhibit Breast Cancer Cell Proliferation and Induce Apoptosis without Affecting Normal Cells | Allan, Ghada; Quadid-Ahidouch, H.; Sánchez-Fernández, Elena M. CSIC ORCID; Rísquez-Cuadro, Rocio; García Fernández, José Manuel CSIC ORCID; Ortiz-Mellet, Carmen; Ahidouch, Ahmed | artículo |
openAccess | | 30-jun-2019 | Polyfluoroalkyl Glycolipid Mimetics as Immunomodulatory Agents | Sánchez-Fernández, Elena M. CSIC ORCID; García-Moreno, Mª Isabel; Arroba, Ana I. CSIC ORCID; Padrón, José M.; García-Hernández, Raquel CSIC ORCID; Gamarro, Francisco; García Fernández, José Manuel CSIC ORCID; Masgrau, Laura; Ortiz Mellet, Carmen | comunicación de congreso |
openAccess | | 2019 | sp 2 -Iminosugar glycolipids as inhibitors of lipopolysaccharide-mediated human dendritic cell activation in vitro and of acute inflammation in mice in vivo | Schaeffer, Evelyne; Sánchez-Fernández, Elena M. CSIC ORCID; Gonçalves-Pereira, Rita; Flacher, Vincent; Lamon, Delphine; Duval, Monique; Fauny, J-D.; García Fernández, José Manuel CSIC ORCID; Ortiz-Mellet, Carmen | artículo |
closedAccess | | 2012 | Sp 2-iminosugar O-, S-, and N-glycosides as conformational mimics of ¿-linked disaccharides; Implications for glycosidase inhibition | Sánchez-Fernández, Elena M. CSIC ORCID; Rísquez-Cuadro, Rocio; Ortiz-Mellet, Carmen; García Fernández, José Manuel CSIC ORCID; Nieto, Pedro M. CSIC ORCID ; Angulo, Jesús CSIC ORCID | artículo |
closedAccess | | dic-2017 | sp2-Iminosugar α-glucosidase inhibitor 1-C-octyl-2-oxa-3-oxocastanospermine specifically affected breast cancer cell migration through Stim1, β1-integrin, and FAK signaling pathways | Gueder, Nahla; Allan, Ghada; Telliez, Marie-Sophie; Hague, Frédéric; Fernandez, José M.; Sánchez-Fernández, Elena M. CSIC ORCID; Ortiz-Mellet, Carmen; Ahidouch, Ahmed; Ouadid-Ahidouch, Halima | artículo |
closedAccess | | 2014 | Synthesis of multibranched australine derivatives from reducing castanospermine analogues through the amadori rearrangement of gem -diamine intermediates: Selective inhibitors of β-glucosidase | Sánchez-Fernández, Elena M. CSIC ORCID; Álvarez, Eleuterio CSIC ORCID ; Ortiz-Mellet, Carmen; García Fernández, José Manuel CSIC ORCID | artículo |
closedAccess | | 15-jun-2010 | Synthesis of N-, S-, and C-glycoside castanospermine analogues with selective neutral α-glucosidase inhibitory activity as antitumour agents | Sánchez-Fernández, Elena M. CSIC ORCID; Rísquez-Cuadro, Rocio; Chasseraud, Maud; Ahidouch, Ahmed; Ortiz-Mellet, Carmen; Ouadid-Ahidouch, Halima; García Fernández, José Manuel CSIC ORCID | artículo |
closedAccess | | 2019 | Synthesis of polyfluoroalkyl sp2-iminosugar glycolipids and evaluation of their immunomodulatory properties towards anti-tumor, anti-leishmanial and anti-inflammatory therapies | Sánchez-Fernández, Elena M. CSIC ORCID; García-Moreno, M. Isabel; Arroba, Ana I. CSIC ORCID; Aguilar-Diosdado, Manuel; Padrón, José M.; García-Hernández, Raquel CSIC ORCID; Gamarro, Francisco; Fustero, Santos; Sánchez-Aparicio, J.E.; Masgrau, Laura; García Fernández, José Manuel CSIC ORCID; Ortiz Mellet, Carmen | artículo |
openAccess | | 11-dic-2021 | Synthesis of sp2 -Iminosugar Selenoglycolipids as Multitarget Drug Candidates with Antiproliferative, Leishmanicidal and Anti-Inflammatory Properties | Sánchez-Fernández, Elena M. CSIC ORCID; García-Hernández, Raquel CSIC ORCID; Gamarro, F.; Arroba, A. I.; Aguilar-Diosdado, Manuel; Padrón, José M.; García Fernández, José Manuel CSIC ORCID; Ortiz Mellet, Carmen | artículo |