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| Derechos | Preview | Fecha Public. | Título | Autor(es) | Tipo |
| openAccess | | may-2023 | A multi-specific, multi-affinity antibody platform neutralizes sarbecoviruses and confers protection against SARS-CoV-2 in vivo | Burn Aschner, Clare; Muthuraman, Krithika; Kucharska, Iga; Cui, Hong; Prieto, Katherine; Nair, Manoj S.; Wang, Maple; Huang, Yaoxing; Christie-Holmes, Natasha; Poon, Betty; Lam, Jessica; Sultana, Azmiri; Kozak, Robert; Mubareka, Samira; Rubinstein, John L.; Rujas, Edurne CSIC ORCID; Treanor, Bebhinn; Ho, David D.; Jetha, Arif; Julien, Jean-Philippe | artículo |
| openAccess |  | 18-ago-2020 | Affinity for the Interface Underpins Potency of Antibodies Operating In Membrane Environments | Rujas, Edurne CSIC ORCID; Insausti, Sara CSIC ORCID; Leaman, Daniel P.; Carravilla, Pablo CSIC ORCID; González-Resines, Saúl; Monceaux, Valérie; Sánchez-Eugenia, Rubén CSIC ORCID; García-Porras, Miguel CSIC; Iloro, Ibon CSIC ORCID; Zhang, Lei; Elortza, Félix; Julien, Jean-Philippe; Sáez-Cirión, Asier; Zwick, Michael B.; Eggeling, Christian; Ojida, Akio; Domene, Carmen; Caaveiro, José M. M.; Nieva, José Luis CSIC ORCID | artículo |
| closedAccess |  | 14-ago-2020 | Cholesterol Constrains the Antigenic Configuration of the Membrane-Proximal Neutralizing HIV-1 Epitope | Torralba, Johana CSIC; Arada, Igor de la CSIC ORCID; Carravilla, Pablo CSIC ORCID; Insausti, Sara CSIC ORCID; Rujas, Edurne CSIC ORCID; Largo, Eneko CSIC ORCID; Eggeling, Christian; Arrondo, José Luis R.; Apellániz, Beatriz CSIC ORCID; Nieva, José Luis CSIC ORCID | artículo |
| openAccess |  | 14-mar-2022 | Dual inhibition of vacuolar ATPase and TMPRSS2 is required for complete blockade of SARS-CoV-2 entry into cells | Icho, Simoun; Rujas, Edurne CSIC ORCID; Muthuraman, Krithika; Tam, John; Liang, Huazhu; Harms, Shelby; Liao, Mingmin; Falzarano, Darryl; Julien, Jean-Philippe; Melnyk, Roman A. | preprint |
| openAccess |  | 15-jun-2022 | Dual Inhibition of Vacuolar-ATPase and TMPRSS2 Is Required for Complete Blockade of SARS-CoV-2 Entry into Cells | Icho, Simoun; Rujas, Edurne CSIC ORCID; Muthuraman, Krithika; Tam, John; Liang, Huazhu; Harms, Shelby; Liao, Mingmin; Falzarano, Darryl; Julien, Jean-Philippe; Melnyk, Roman A. | artículo |
| openAccess |  | 21-ene-2022 | Engineering pan-HIV-1 neutralization potency through multispecific antibody avidity | Rujas, Edurne CSIC ORCID; Cui, Hong; Burnie, Jonathan; Burn Aschner, Clare; Zhao, Tiantian; Insausti, Sara CSIC ORCID; Muthuraman, Krithika; Semesi, Anthony; Ophel, Jasper; Seaman, Michael S.; Guzzo, Christina; Treanor, Bebhinn; Julien, Jean-Philippe | artículo |
| openAccess |  | 24-sep-2021 | Focal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profile | Rujas, Edurne CSIC ORCID; Leaman, Daniel P.; Insausti, Sara CSIC ORCID; Carravilla, Pablo CSIC ORCID; García-Porras, Miguel CSIC; Largo, Eneko CSIC ORCID; Morillo, Izaskun CSIC ORCID; Sánchez-Eugenia, Rubén CSIC ORCID; Zhang, Lei; Cui, Hong; Iloro, Ibon CSIC ORCID; Elortza, Félix; Julien, Jean-Philippe; Eggeling, Christian; Zwick, Michael B.; Caaveiro, José M. M.; Nieva, José Luis CSIC ORCID | artículo |
| openAccess |  | sep-2022 | Functional Delineation of a Protein-Membrane Interaction Hotspot Site on the HIV-1 Neutralizing Antibody 10E8 | Insausti, Sara CSIC ORCID; García-Porras, Miguel CSIC; Torralba, Johana CSIC; Morillo, Izaskun CSIC ORCID; Ramos Caballero, Ander; Arada, Igor de la CSIC ORCID; Apellániz, Beatriz CSIC ORCID; Caaveiro, José M. M.; Carravilla, Pablo CSIC ORCID; Eggeling, Christian; Rujas, Edurne CSIC ORCID; Nieva, José Luis CSIC ORCID | artículo |
| openAccess |  | 1-dic-2021 | Lyophilized, thermostable Spike or RBD immunogenic liposomes induce protective immunity against SARS-CoV-2 in mice | Mabrouk, Moustafa T.; Chiem, Kevin; Rujas, Edurne CSIC ORCID; Huang, Wei-Chiao; Jahagirdar, Dushyant; Quinn, Breandan; Surendran Nair, Meera; Nissly, Ruth; Cavener, Victoria; Boyle, Nina; Sornberger, Ty; Kuchipudi, Suresh; Ortega, Joaquín; Julien, Jean-Philippe; Martínez-Sobrido, Luis; Lovell, Jonathan | artículo |
| openAccess |  | 25-abr-2023 | Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses | Kassardjian, Audrey; Sun, Eric; Sookhoo, Jamie; Muthuraman, Krithika; Boligan, Kayluz Frias; Kucharska, Iga; Rujas, Edurne CSIC ORCID; Jetha, Arif; Branch, Donald R.; Babiuk, Shawn; Barber, Brian; Julien, Jean-Philippe | artículo |
| openAccess |  | 18-nov-2022 | Molecular recognition of a membrane-anchored HIV-1 pan-neutralizing epitope | Torralba, Johana CSIC; Arada, Igor de la CSIC ORCID; Partida-Hanón, Angélica CSIC ORCID; Rujas, Edurne CSIC ORCID; Arribas, Madalen; Insausti, Sara CSIC ORCID; Valotteau, Claire; Valle, Javier; Andreu, David; Caaveiro, José M. M.; Jiménez, M. Angeles CSIC ORCID ; Apellániz, Beatriz CSIC ORCID; Redondo-Morata, Lorena; Nieva, José Luis CSIC ORCID | artículo |
| closedAccess |  | 13-abr-2021 | Multiscale interactome analysis coupled with off-target drug predictions reveals drug repurposing candidates for human coronavirus disease | Sugiyama, Michel G.; Cui, Haotian; Redka, Dar’ya S.; Karimzadeh, Mehran; Rujas, Edurne CSIC ORCID; Maan, Hassaan; Hayat, Sikander; Cheung, Kyle; Misra, Rahul; McPhee, Joseph B.; Viirre, Russell D.; Haller, Andrew; Botelho, Roberto J.; Karshafian, Raffi; Sabatinos, Sarah A.; Fairn, Gregory D.; Madani Tonekaboni, Seyed Ali; Windemuth, Andreas; Julien, Jean-Philippe; Shahani, Vijay; MacKinnon, Stephen S.; Wang, Bo; Antonescu, Costin N. | preprint |
| openAccess |  | 2-dic-2021 | Multiscale interactome analysis coupled with off-target drug predictions reveals drug repurposing candidates for human coronavirus disease | Sugiyama, Michel G.; Cui, Haotian; Redka, Dar’ya S.; Karimzadeh, Mehran; Rujas, Edurne CSIC ORCID; Maan, Hassaan; Hayat, Sikander; Cheung, Kyle; Misra, Rahul; McPhee, Joseph B.; Viirre, Russell D.; Haller, Andrew; Botelho, Roberto J.; Karshafian, Raffi; Sabatinos, Sarah A.; Fairn, Gregory D.; Madani Tonekaboni, Seyed Ali; Windemuth, Andreas; Julien, Jean-Philippe; Shahani, Vijay; MacKinnon, Stephen S.; Wang, Bo; Antonescu, Costin N. | artículo |
| openAccess |  | 16-oct-2020 | Multivalency transforms SARS-CoV-2 antibodies into broad and ultrapotent neutralizers | Rujas, Edurne CSIC ORCID; Kucharska, Iga; Tan, Yong Zi; Benlekbir, Samir; Cui, Hong; Zhao, Tiantian; Wasney, Gregory A.; Budylowski, Patrick; Guvenc, Furkan; Newton, Jocelyn C.; Sicard, Taylor; Semesi, Anthony; Muthuraman, Krithika; Nouanesengsy, Amy; Prieto, Katherine; Bueler, Stephanie A.; Youssef, Sawsan; Liao-Chan, Sindy; Glanville, Jacob; Christie-Holmes, Natasha; Mubareka, Samira; Gray-Owen, Scott D.; Rubinstein, John L.; Treanor, Bebhinn; Julien, Jean-Philippe | preprint |
| openAccess |  | 16-jun-2021 | Multivalency transforms SARS-CoV-2 antibodies into ultrapotent neutralizers | Rujas, Edurne CSIC ORCID; Kucharska, Iga; Tan, Yong Zi; Benlekbir, Samir; Cui, Hong; Zhao, Tiantian; Wasney, Gregory A.; Budylowski, Patrick; Guvenc, Furkan; Newton, Jocelyn C.; Sicard, Taylor; Semesi, Anthony; Muthuraman, Krithika; Nouanesengsy, Amy; Burn Aschner, Clare; Prieto, Katherine; Bueler, Stephanie A.; Youssef, Sawsan; Liao-Chan, Sindy; Glanville, Jacob; Christie-Holmes, Natasha; Mubareka, Samira; Gray-Owen, Scott D.; Rubinstein, John L.; Treanor, Bebhinn; Julien, Jean-Philippe | artículo |
| openAccess |  | 2016 | Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface | Rujas, Edurne CSIC ORCID; Caaveiro, J. M. M.; Partida-Hanón, Angélica CSIC ORCID; Gulzar, N.; Morante, K.; Apellániz, Beatriz CSIC ORCID; García-Porras, M.; Bruix, M. CSIC ORCID ; Tsumoto, K.; Scott, J. K.; Jiménez, M. Angeles CSIC ORCID ; Nieva, José Luis CSIC ORCID | artículo |
| openAccess |  | 8-oct-2020 | Structural characterization of the ICOS/ICOS-L immune complex reveals high molecular mimicry by therapeutic antibodies | Rujas, Edurne CSIC ORCID; Cui, Hong; Sicard, Taylor; Semesi, Anthony; Julien, Jean-Philippe | artículo |
| closedAccess |  | 2014 | Structure and immunogenicity of a peptide vaccine, including the complete HIV-1 gp41 2F5 epitope: Implications for antibody recognition mechanism and immunogen design | Serrano, Soroya CSIC ORCID; Araujo, Aitziber CSIC; Apellániz, Beatriz CSIC ORCID; Bryson, Steve; Carravilla, Pablo CSIC ORCID; Arada, Igor de la CSIC ORCID; Huarte, Nerea CSIC; Rujas, Edurne CSIC ORCID; Pai, E. F.; Arrondo, José Luis R.; Domene, Carme; Jiménez, M. Angeles CSIC ORCID ; Nieva, José Luis CSIC ORCID | artículo |
| closedAccess |  | 2017 | Structure-Related Roles for the Conservation of the HIV-1 Fusion Peptide Sequence Revealed by Nuclear Magnetic Resonance | Serrano, Soroya CSIC ORCID; Huarte, Nerea CSIC; Rujas, Edurne CSIC ORCID; Andreu, D.; Nieva, José Luis CSIC ORCID; Jiménez, M. Angeles CSIC ORCID | artículo |
| openAccess |  | 25-abr-2023 | Supplemental information Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses | Kassardjian, Audrey; Sun, Eric; Sookhoo, Jamie; Muthuraman, Krithika; Boligan, Kayluz Frias; Kucharska, Iga; Rujas, Edurne CSIC ORCID; Jetha, Arif; Branch, Donald R.; Babiuk, Shawn; Barber, Brian; Julien, Jean-Philippe | dataset |
