Rights | Preview | Issue Date | Title | Author(s) | Type |
openAccess |  | 27-Jun-2017 | Desarrollo y validación experimental de un método para la obtención de estructuras de complejos ligando/receptor basado en Resonancia Magnética Nuclear | Rodríguez-Salarichs, Javier | tesis doctoral |
openAccess |  | 8-May-2011 | High-throughput preparation of alkyl 4-aryl substituted-2-methyl-6-thioxo-1,4,5,6-tetrahydropyridine-3-carboxylates under microwave irradiation | Rodríguez, Hortensia; Coro, Julieta; Lam, Anabel; Salfrán, Esperanza; Rodríguez-Salarichs, Javier; Suarez, Margarita; Albericio, Fernando; Martín, Nazario | artículo |
openAccess |  | 19-Aug-2011 | Insights into the interaction of discodermolide and docetaxel with tubulin. Mapping the binding sites of microtubule-stabilizing agents by using an integrated NMR and computational approach | Canales, Ángeles ; Rodríguez-Salarichs, Javier; Trigili, Chiara ; Nieto, Lidia ; Coderch, Claire; Andreu, José Manuel ; Paterson, Ian; Jiménez-Barbero, Jesús ; Díaz, José Fernando | artículo |
openAccess |  | 3-Jun-2017 | Modification of C-seco taxoids through ring tethering and substituent replacement leading to effective agents against tumor drug resistance mediated by βIII-Tubulin and P-glycoprotein (P-gp) overexpressions. | Tang, Yong; Rodríguez-Salarichs, Javier; Estévez-Gallego, Juan ; Balaguer, Francisco de Asís; Redondo-Horcajo, Mariano ; Lucena-Agell, Daniel ; Barasoain, Isabel ; Díaz, José Fernando ; Fang, Wei-shuo S. | artículo |
openAccess |  | 21-Dec-2011 | Modulation of microtubule interprotofilament interactions by modified taxanes | Matesanz, Ruth ; Rodríguez-Salarichs, Javier; Pera, Benet ; Canales, Ángeles ; Andreu, José Manuel ; Jiménez-Barbero, Jesús ; Bras, Wim; Nogales, Aurora ; Fang, Wei-shuo S.; Díaz, José Fernando | artículo |
openAccess |  | 13-Feb-2014 | Molecular Recognition of Epothilones by Microtubules and Tubulin Dimers Revealed by Biochemical and NMR Approaches | Canales, Ángeles ; Nieto, Lidia ; Rodríguez-Salarichs, Javier; Andreu, José Manuel ; Jiménez-Barbero, Jesús ; Díaz, José Fernando | artículo |
embargoedAccess |  | 13-Jul-2020 | Structural basis of noscapine activation for tubulin binding | Oliva, María A.; Prota, Andrea E.; Rodríguez-Salarichs, Javier; Wenxin, Gu; Bennani, Y. L.; Jiménez-Barbero, Jesús ; Bargsten, Katja; Canales, Ángeles ; Steinmetz, Michel O.; Díaz, José Fernando | artículo |
openAccess |  | 3-Aug-2016 | Synthesis, biological profiling and determination of the tubulin-bound conformation of 12-Aza-epothilones (azathilones) | Jantsch, Andrea; Nieto, Lidia ; Gertsch, Jürg; Rodríguez-Salarichs, Javier; Matesanz, Ruth ; Jiménez-Barbero, Jesús ; Díaz, José Fernando ; Canales, Ángeles ; Altmann, Karl-Heinz | artículo |
openAccess |  | 3-Aug-2016 | Synthesis, Biological Profiling and Determination of the Tubulin-Bound Conformation of 12-Aza-Epothilones (Azathilones) | Jantsch, Andrea; Nieto, Lidia ; Gertsch, Jürg; Rodríguez-Salarichs, Javier; Matesanz, Ruth ; Jiménez-Barbero, Jesús ; Díaz, José Fernando ; Canales, Ángeles ; Altmann, Karl-Heinz | artículo |
closedAccess |  | 3-Apr-2019 | Synthesis, profiling, and bioactive conformation of trans-Cyclopropyl Epothilones | Kuzniewski, Christian N.; Glauser, Simon; Gaugaz, Fabienne Z.; Schiess, Raphael; Rodríguez-Salarichs, Javier; Vetterli, Stefan; Horlacher, Oliver P.; Gertsch, Jürg; Redondo-Horcajo, Mariano ; Canales, Ángeles ; Jiménez-Barbero, Jesús ; Díaz, José Fernando ; Altmann, Karl-Heinz | artículo |
openAccess |  | 19-Jun-2014 | Taxanes with high potency inducing tubulin assembly overcome tumoural cell resistances | Matesanz, Ruth ; Trigili, Chiara ; Rodríguez-Salarichs, Javier; Pera, Benet ; Jiménez-Barbero, Jesús ; Canales, Ángeles ; Barasoain, Isabel ; Díaz, José Fernando | artículo |
openAccess |  | 22-Jun-2017 | Triazolopyrimidines Are Microtubule-Stabilizing Agents that Bind the Vinca Inhibitor Site of Tubulin | Sáez-Calvo, Gonzalo; Balaguer, Francisco de Asís; Barasoain, Isabel ; Rodríguez-Salarichs, Javier; Muñoz-Hernández, Hugo; Berbís, Manuel Álvaro ; Peñalva, Miguel Ángel ; Matesanz, Ruth ; Canales, Ángeles ; Jiménez-Barbero, Jesús ; Andreu, José Manuel ; Díaz, José Fernando | artículo |
openAccess |  | 12-Oct-2017 | Zampanolide binding to tubulin indicates crosstalk of taxane site with colchicine and nucleotide sites | Field, Jessica J.; Pera, Benet ; Estévez-Gallego, Juan ; Rodríguez-Salarichs, Javier; Sáez-Calvo, Gonzalo; Andreu, José Manuel ; Díaz, José Fernando | artículo |
openAccess |  | 22-Jun-2012 | Zampanolide, a potent new microtubule stabilizing agent, covalently reacts with the taxane luminal site in both tubulin alpha-beta-heterodimers and microtubules | Field, Jessica J.; Pera, Benet ; Calvo, Enrique; Canales, Ángeles ; Zurwerra, Didier; Trigili, Chiara ; Rodríguez-Salarichs, Javier; Matesanz, Ruth ; Kanakkanthara, Arun; Wakefield, St. John; Singh, A. Jonathan; Jiménez-Barbero, Jesús ; Northcote, Peter; Miller, John H.; López, Juan Antonio; Hamel, Ernest; Barasoain, Isabel ; Altmann, Karl-Heinz; Díaz, José Fernando | artículo |