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Browsing by Author Rodríguez-Salarichs, Javier

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Showing results 1 to 12 of 12
RightsPreviewIssue DateTitleAuthor(s)Type
openAccessarkivoc_2011.pdf.jpg8-May-2011High-throughput preparation of alkyl 4-aryl substituted-2-methyl-6-thioxo-1,4,5,6-tetrahydropyridine-3-carboxylates under microwave irradiationRodríguez, Hortensia; Coro, Julieta; Lam, Anabel; Salfrán, Esperanza; Rodríguez-Salarichs, Javier; Suarez, Margarita; Albericio, Fernando; Martín, NazarioArtículo
openAccess2011 Canales_et_al.pdf.jpg19-Aug-2011Insights into the interaction of discodermolide and docetaxel with tubulin. Mapping the binding sites of microtubule-stabilizing agents by using an integrated NMR and computational approachCanales, Ángeles ; Rodríguez-Salarichs, Javier; Trigili, Chiara ; Nieto, Lidia ; Coderch, Claire; Andreu, José Manuel ; Paterson, Ian; Jiménez-Barbero, Jesús ; Díaz, José Fernando Artículo
openAccess2017 Tang et al.pdf.jpg3-Jun-2017Modification of C-seco taxoids through ring tethering and substituent replacement leading to effective agents against tumor drug resistance mediated by βIII-Tubulin and P-glycoprotein (P-gp) overexpressions.Tang, Yong; Rodríguez-Salarichs, Javier; Estévez Gallego, J.; Balaguer, Francisco de Asís; Redondo-Horcajo, Mariano ; Lucena-Agell, Daniel; Barasoain, Isabel ; Díaz, José Fernando ; Fang, Wei-shuo S.Artículo
openAccessMatesanz_et_al_2011 Biophysical Journal.pdf.jpg21-Dec-2011Modulation of microtubule interprotofilament interactions by modified taxanesMatesanz, Ruth ; Rodríguez-Salarichs, Javier; Pera, Benet ; Canales, Ángeles ; Andreu, José Manuel ; Jiménez-Barbero, Jesús ; Bras, Wim; Nogales, Aurora ; Fang, Wei-shuo S.; Díaz, José Fernando Artículo
openAccessCanales et al 2013 ACS.pdf.jpg13-Feb-2014Molecular Recognition of Epothilones by Microtubules and Tubulin Dimers Revealed by Biochemical and NMR ApproachesCanales, Ángeles ; Nieto, Lidia ; Rodríguez-Salarichs, Javier; Andreu, José Manuel ; Jiménez-Barbero, Jesús ; Díaz, José Fernando Artículo
openAccessmolecules-2016.pdf.jpg3-Aug-2016Synthesis, biological profiling and determination of the tubulin-bound conformation of 12-Aza-epothilones (azathilones)Jantsch, Andrea; Nieto, Lidia ; Gertsch, Jürg; Rodríguez-Salarichs, Javier; Matesanz, Ruth ; Jiménez-Barbero, Jesús ; Díaz, José Fernando ; Canales, Ángeles ; Altmann, Karl-HeinzArtículo
openAccessmolecules-21-01010.pdf.jpg3-Aug-2016Synthesis, Biological Profiling and Determination of the Tubulin-Bound Conformation of 12-Aza-Epothilones (Azathilones)Jantsch, Andrea; Nieto, Lidia ; Gertsch, Jürg; Rodríguez-Salarichs, Javier; Matesanz, Ruth ; Jiménez-Barbero, Jesús ; Díaz, José Fernando ; Canales, Ángeles ; Altmann, Karl-HeinzArtículo
closedAccessrestringido.pdf.jpg3-Apr-2019Synthesis, profiling, and bioactive conformation of trans-Cyclopropyl EpothilonesKuzniewski, Christian N.; Glauser, Simon; Gaugaz, Fabienne Z.; Schiess, Raphael; Rodríguez-Salarichs, Javier; Vetterli, Stefan; Horlacher, Oliver P.; Gertsch, Jürg; Redondo-Horcajo, Mariano ; Canales, Ángeles ; Jiménez-Barbero, Jesús ; Díaz, José Fernando ; Altmann, Karl-HeinzArtículo
openAccessMatesanz et al_2014 _Bioorganic Medicinal Chemistry.pdf.jpg19-Jun-2014Taxanes with high potency inducing tubulin assembly overcome tumoural cell resistancesMatesanz, Ruth ; Trigili, Chiara ; Rodríguez-Salarichs, Javier; Pera, Benet ; Jiménez-Barbero, Jesús ; Canales, Ángeles ; Barasoain, Isabel ; Díaz, José Fernando Artículo
openAccessSaez-Calvo-et-al.2017.pdf.jpg22-Jun-2017Triazolopyrimidines Are Microtubule-Stabilizing Agents that Bind the Vinca Inhibitor Site of TubulinSáez-Calvo, Gonzalo; Balaguer, Francisco de Asís; Barasoain, Isabel ; Rodríguez-Salarichs, Javier; Muñoz-Hernández, Hugo; Berbís, Manuel Álvaro ; Peñalva, Miguel Ángel ; Matesanz, Ruth ; Canales, Ángeles ; Jiménez-Barbero, Jesús ; Andreu, José Manuel ; Díaz, José Fernando Artículo
openAccessJNP_2017 Field et al.pdf.jpg12-Oct-2017Zampanolide binding to tubulin indicates crosstalk of taxane site with colchicine and nucleotide sitesField, Jessica J.; Pera, Benet ; Estévez Gallego, J.; Rodríguez-Salarichs, Javier; Sáez-Calvo, Gonzalo; Andreu, José Manuel ; Díaz, José Fernando Artículo
openAccessField et al 2012_Chemistry and Biology.pdf.jpg22-Jun-2012Zampanolide, a potent new microtubule stabilizing agent, covalently reacts with the taxane luminal site in both tubulin alpha-beta-heterodimers and microtubulesField, Jessica J.; Pera, Benet ; Calvo, Enrique; Canales, Ángeles ; Zurwerra, Didier; Trigili, Chiara ; Rodríguez-Salarichs, Javier; Matesanz, Ruth ; Kanakkanthara, Arun; Wakefield, St. John; Singh, A. Jonathan; Jiménez-Barbero, Jesús ; Northcote, Peter; Miller, John H.; López, Juan Antonio; Hamel, Ernest; Barasoain, Isabel ; Altmann, Karl-Heinz; Díaz, José Fernando Artículo