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Browsing by Author Rodríguez-Salarichs, Javier

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Showing results 1 to 17 of 17
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openAccessTesis_Javier_Rodríguez_Salarichs_UAM.pdf.jpg27-Jun-2017Desarrollo y validación experimental de un método para la obtención de estructuras de complejos ligando/receptor basado en Resonancia Magnética NuclearRodríguez-Salarichs, Javiertesis doctoral
openAccessarkivoc_2011.pdf.jpg8-May-2011High-throughput preparation of alkyl 4-aryl substituted-2-methyl-6-thioxo-1,4,5,6-tetrahydropyridine-3-carboxylates under microwave irradiationRodríguez, Hortensia; Coro, Julieta; Lam, Anabel; Salfrán, Esperanza; Rodríguez-Salarichs, Javier; Suarez, Margarita; Albericio, Fernando; Martín, Nazarioartículo
openAccess2011 Canales_et_al.pdf.jpg19-Aug-2011Insights into the interaction of discodermolide and docetaxel with tubulin. Mapping the binding sites of microtubule-stabilizing agents by using an integrated NMR and computational approachCanales, Ángeles CSIC ORCID; Rodríguez-Salarichs, Javier; Trigili, Chiara CSIC; Nieto, Lidia CSIC; Coderch, Claire; Andreu, José Manuel CSIC ORCID ; Paterson, Ian; Jiménez-Barbero, Jesús CSIC ORCID; Díaz, José Fernando CSIC ORCID artículo
openAccess2017 Tang et al.pdf.jpg3-Jun-2017Modification of C-seco taxoids through ring tethering and substituent replacement leading to effective agents against tumor drug resistance mediated by βIII-Tubulin and P-glycoprotein (P-gp) overexpressions.Tang, Yong; Rodríguez-Salarichs, Javier; Estévez-Gallego, Juan CSIC ORCID ; Balaguer, Francisco de Asís; Redondo-Horcajo, Mariano CSIC ORCID ; Lucena-Agell, Daniel CSIC ORCID ; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Fang, Wei-shuo S.artículo
openAccessMatesanz_et_al_2011 Biophysical Journal.pdf.jpg21-Dec-2011Modulation of microtubule interprotofilament interactions by modified taxanesMatesanz, Ruth CSIC ; Rodríguez-Salarichs, Javier; Pera, Benet CSIC; Canales, Ángeles CSIC ORCID; Andreu, José Manuel CSIC ORCID ; Jiménez-Barbero, Jesús CSIC ORCID; Bras, Wim; Nogales, Aurora CSIC ORCID; Fang, Wei-shuo S.; Díaz, José Fernando CSIC ORCID artículo
openAccessCanales et al 2013 ACS.pdf.jpg13-Feb-2014Molecular Recognition of Epothilones by Microtubules and Tubulin Dimers Revealed by Biochemical and NMR ApproachesCanales, Ángeles CSIC ORCID; Nieto, Lidia CSIC; Rodríguez-Salarichs, Javier; Andreu, José Manuel CSIC ORCID ; Jiménez-Barbero, Jesús CSIC ORCID; Díaz, José Fernando CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg16-Jul-2013New interfacial microtubule inhibitors of marine origin, PM050489/PM060184, with potent antitumor activity and a distinct mechanismPera, Benet CSIC; Barasoain, Isabel CSIC ; Pantazopoulou, Areti CSIC ORCID; Canales, Ángeles CSIC ORCID; Matesanz, Ruth CSIC ; Rodríguez-Salarichs, Javier; García-Fernández, Luis F. CSIC; Moneo, Victoria; Jiménez-Barbero, Jesús CSIC ORCID; Galmarini, Carlos M.; Cuevas, Carmen; Peñalva, Miguel Ángel CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Andreu, José Manuel CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg12-Aug-2016Structural and Biochemical Characterization of the Interaction of Tubulin with Potent Natural Analogues of PodophyllotoxinAntúnez-Mojica, Mayra; Rodríguez-Salarichs, Javier; Redondo-Horcajo, Mariano CSIC ORCID ; León, Alejandra; Barasoain, Isabel CSIC ; Canales, Ángeles CSIC ORCID; Cañada, F. Javier ; Jiménez-Barbero, Jesús CSIC ORCID; Álvarez, Laura CSIC ORCID; Díaz, José Fernando CSIC ORCID artículo
openAccessacs.jmedchem_Oliva_2020.pdf.jpg13-Jul-2020Structural basis of noscapine activation for tubulin bindingOliva, María A. CSIC ORCID ; Prota, Andrea E.; Rodríguez-Salarichs, Javier; Wenxin, Gu; Bennani, Y. L.; Jiménez-Barbero, Jesús CSIC ORCID; Bargsten, Katja; Canales, Ángeles CSIC ORCID; Steinmetz, Michel O.; Díaz, José Fernando CSIC ORCID artículo
openAccessmolecules-21-01010.pdf.jpg3-Aug-2016Synthesis, Biological Profiling and Determination of the Tubulin-Bound Conformation of 12-Aza-Epothilones (Azathilones)Jantsch, Andrea; Nieto, Lidia CSIC; Gertsch, Jürg; Rodríguez-Salarichs, Javier; Matesanz, Ruth CSIC ; Jiménez-Barbero, Jesús CSIC ORCID; Díaz, José Fernando CSIC ORCID ; Canales, Ángeles CSIC ORCID; Altmann, Karl-Heinzartículo
openAccessmolecules-2016.pdf.jpg3-Aug-2016Synthesis, biological profiling and determination of the tubulin-bound conformation of 12-Aza-epothilones (azathilones)Jantsch, Andrea; Nieto, Lidia CSIC; Gertsch, Jürg; Rodríguez-Salarichs, Javier; Matesanz, Ruth CSIC ; Jiménez-Barbero, Jesús CSIC ORCID; Díaz, José Fernando CSIC ORCID ; Canales, Ángeles CSIC ORCID; Altmann, Karl-Heinzartículo
closedAccessrestringido.pdf.jpg3-Apr-2019Synthesis, profiling, and bioactive conformation of trans-Cyclopropyl EpothilonesKuzniewski, Christian N.; Glauser, Simon; Gaugaz, Fabienne Z.; Schiess, Raphael; Rodríguez-Salarichs, Javier; Vetterli, Stefan; Horlacher, Oliver P.; Gertsch, Jürg; Redondo-Horcajo, Mariano CSIC ORCID ; Canales, Ángeles CSIC ORCID; Jiménez-Barbero, Jesús CSIC ORCID; Díaz, José Fernando CSIC ORCID ; Altmann, Karl-Heinzartículo
openAccessMatesanz et al_2014 _Bioorganic Medicinal Chemistry.pdf.jpg19-Jun-2014Taxanes with high potency inducing tubulin assembly overcome tumoural cell resistancesMatesanz, Ruth CSIC ; Trigili, Chiara CSIC; Rodríguez-Salarichs, Javier; Pera, Benet CSIC; Jiménez-Barbero, Jesús CSIC ORCID; Canales, Ángeles CSIC ORCID; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID artículo
openAccessSaez-Calvo-et-al.2017.pdf.jpg22-Jun-2017Triazolopyrimidines Are Microtubule-Stabilizing Agents that Bind the Vinca Inhibitor Site of TubulinSáez-Calvo, Gonzalo; Balaguer, Francisco de Asís; Barasoain, Isabel CSIC ; Rodríguez-Salarichs, Javier; Muñoz-Hernández, Hugo; Berbís, Manuel Álvaro CSIC; Peñalva, Miguel Ángel CSIC ORCID ; Matesanz, Ruth CSIC ; Canales, Ángeles CSIC ORCID; Jiménez-Barbero, Jesús CSIC ORCID; Andreu, José Manuel CSIC ORCID ; Díaz, José Fernando CSIC ORCID artículo
openAccess8-Feb-2021Versatile lipases from the Candida rugosa-like family: a mechanistic insight using computational approachesRodríguez-Salarichs, Javier; García de Lacoba, Mario CSIC ORCID ; Prieto, Alicia CSIC ORCID ; Martínez, María Jesús CSIC ORCID ; Barriuso, Jorge CSIC ORCID artículo
openAccessJNP_2017 Field et al.pdf.jpg12-Oct-2017Zampanolide binding to tubulin indicates crosstalk of taxane site with colchicine and nucleotide sitesField, Jessica J.; Pera, Benet CSIC; Estévez-Gallego, Juan CSIC ORCID ; Rodríguez-Salarichs, Javier; Sáez-Calvo, Gonzalo; Andreu, José Manuel CSIC ORCID ; Díaz, José Fernando CSIC ORCID artículo
openAccessField et al 2012_Chemistry and Biology.pdf.jpg22-Jun-2012Zampanolide, a potent new microtubule stabilizing agent, covalently reacts with the taxane luminal site in both tubulin alpha-beta-heterodimers and microtubulesField, Jessica J.; Pera, Benet CSIC; Calvo, Enrique; Canales, Ángeles CSIC ORCID; Zurwerra, Didier; Trigili, Chiara CSIC; Rodríguez-Salarichs, Javier; Matesanz, Ruth CSIC ; Kanakkanthara, Arun; Wakefield, St. John; Singh, A. Jonathan; Jiménez-Barbero, Jesús CSIC ORCID; Northcote, Peter; Miller, John H.; López, Juan Antonio; Hamel, Ernest; Barasoain, Isabel CSIC ; Altmann, Karl-Heinz; Díaz, José Fernando CSIC ORCID artículo