Rights | Preview | Issue Date | Title | Author(s) | Type |
openAccess |  | 27-Jun-2017 | Desarrollo y validación experimental de un método para la obtención de estructuras de complejos ligando/receptor basado en Resonancia Magnética Nuclear | Rodríguez-Salarichs, Javier CSIC | tesis doctoral |
openAccess |  | 8-May-2011 | High-throughput preparation of alkyl 4-aryl substituted-2-methyl-6-thioxo-1,4,5,6-tetrahydropyridine-3-carboxylates under microwave irradiation | Rodríguez, Hortensia; Coro, Julieta; Lam, Anabel; Salfrán, Esperanza; Rodríguez-Salarichs, Javier CSIC; Suarez, Margarita; Albericio, Fernando CSIC ORCID; Martín, Nazario | artículo |
openAccess |  | 19-Aug-2011 | Insights into the interaction of discodermolide and docetaxel with tubulin. Mapping the binding sites of microtubule-stabilizing agents by using an integrated NMR and computational approach | Canales, Ángeles CSIC ORCID; Rodríguez-Salarichs, Javier CSIC; Trigili, Chiara CSIC; Nieto, Lidia CSIC; Coderch, Claire; Andreu, José Manuel CSIC ORCID ; Paterson, Ian; Jiménez-Barbero, Jesús CSIC ORCID; Díaz, José Fernando CSIC ORCID | artículo |
openAccess |  | 3-Jun-2017 | Modification of C-seco taxoids through ring tethering and substituent replacement leading to effective agents against tumor drug resistance mediated by βIII-Tubulin and P-glycoprotein (P-gp) overexpressions. | Tang, Yong; Rodríguez-Salarichs, Javier CSIC; Estévez-Gallego, Juan CSIC ORCID ; Balaguer, Francisco de Asís CSIC ORCID; Redondo-Horcajo, Mariano CSIC ORCID ; Lucena-Agell, Daniel CSIC ORCID ; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID ; Fang, Wei-Shuo | artículo |
openAccess |  | 21-Dec-2011 | Modulation of microtubule interprotofilament interactions by modified taxanes | Matesanz, Ruth CSIC ; Rodríguez-Salarichs, Javier CSIC; Pera, Benet CSIC; Canales, Ángeles CSIC ORCID; Andreu, José Manuel CSIC ORCID ; Jiménez-Barbero, Jesús CSIC ORCID; Bras, Wim; Nogales, Aurora CSIC ORCID; Fang, Wei-Shuo; Díaz, José Fernando CSIC ORCID | artículo |
openAccess |  | 13-Feb-2014 | Molecular Recognition of Epothilones by Microtubules and Tubulin Dimers Revealed by Biochemical and NMR Approaches | Canales, Ángeles CSIC ORCID; Nieto, Lidia CSIC; Rodríguez-Salarichs, Javier CSIC; Andreu, José Manuel CSIC ORCID ; Jiménez-Barbero, Jesús CSIC ORCID; Díaz, José Fernando CSIC ORCID | artículo |
closedAccess |  | 16-Jul-2013 | New interfacial microtubule inhibitors of marine origin, PM050489/PM060184, with potent antitumor activity and a distinct mechanism | Pera, Benet CSIC; Barasoain, Isabel CSIC ; Pantazopoulou, Areti CSIC ORCID; Canales, Ángeles CSIC ORCID; Matesanz, Ruth CSIC ; Rodríguez-Salarichs, Javier CSIC; García-Fernández, Luis F. CSIC; Moneo, Victoria; Jiménez-Barbero, Jesús CSIC ORCID; Galmarini, Carlos M.; Cuevas, Carmen; Peñalva, Miguel Ángel CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Andreu, José Manuel CSIC ORCID | artículo |
closedAccess |  | 12-Aug-2016 | Structural and Biochemical Characterization of the Interaction of Tubulin with Potent Natural Analogues of Podophyllotoxin | Antúnez-Mojica, Mayra; Rodríguez-Salarichs, Javier CSIC; Redondo-Horcajo, Mariano CSIC ORCID ; León, Alejandra; Barasoain, Isabel CSIC ; Canales, Ángeles CSIC ORCID; Cañada, F. Javier ; Jiménez-Barbero, Jesús CSIC ORCID; Álvarez, Laura CSIC ORCID; Díaz, José Fernando CSIC ORCID | artículo |
openAccess |  | 13-Jul-2020 | Structural basis of noscapine activation for tubulin binding | Oliva, María A. CSIC ORCID ; Prota, Andrea E.; Rodríguez-Salarichs, Javier CSIC; Wenxin, Gu; Bennani, Y. L.; Jiménez-Barbero, Jesús CSIC ORCID; Bargsten, Katja; Canales, Ángeles CSIC ORCID; Steinmetz, Michel O.; Díaz, José Fernando CSIC ORCID | artículo |
openAccess |  | 3-Aug-2016 | Synthesis, biological profiling and determination of the tubulin-bound conformation of 12-Aza-epothilones (azathilones) | Jantsch, Andrea; Nieto, Lidia CSIC; Gertsch, Jürg; Rodríguez-Salarichs, Javier CSIC; Matesanz, Ruth CSIC ; Jiménez-Barbero, Jesús CSIC ORCID; Díaz, José Fernando CSIC ORCID ; Canales, Ángeles CSIC ORCID; Altmann, Karl-Heinz | artículo |
closedAccess |  | 3-Apr-2019 | Synthesis, profiling, and bioactive conformation of trans-Cyclopropyl Epothilones | Kuzniewski, Christian N.; Glauser, Simon; Gaugaz, Fabienne Z.; Schiess, Raphael; Rodríguez-Salarichs, Javier CSIC; Vetterli, Stefan; Horlacher, Oliver P.; Gertsch, Jürg; Redondo-Horcajo, Mariano CSIC ORCID ; Canales, Ángeles CSIC ORCID; Jiménez-Barbero, Jesús CSIC ORCID; Díaz, José Fernando CSIC ORCID ; Altmann, Karl-Heinz | artículo |
openAccess |  | 19-Jun-2014 | Taxanes with high potency inducing tubulin assembly overcome tumoural cell resistances | Matesanz, Ruth CSIC ; Trigili, Chiara CSIC; Rodríguez-Salarichs, Javier CSIC; Pera, Benet CSIC; Jiménez-Barbero, Jesús CSIC ORCID; Canales, Ángeles CSIC ORCID; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID | artículo |
openAccess |  | 22-Jun-2017 | Triazolopyrimidines Are Microtubule-Stabilizing Agents that Bind the Vinca Inhibitor Site of Tubulin | Sáez-Calvo, Gonzalo CSIC; Balaguer, Francisco de Asís CSIC ORCID; Barasoain, Isabel CSIC ; Rodríguez-Salarichs, Javier CSIC; Muñoz-Hernández, Hugo CSIC ORCID; Berbís, Manuel Álvaro CSIC; Peñalva, Miguel Ángel CSIC ORCID ; Matesanz, Ruth CSIC ; Canales, Ángeles CSIC ORCID; Jiménez-Barbero, Jesús CSIC ORCID; Andreu, José Manuel CSIC ORCID ; Díaz, José Fernando CSIC ORCID | artículo |
openAccess | | 8-Feb-2021 | Versatile lipases from the Candida rugosa-like family: a mechanistic insight using computational approaches | Rodríguez-Salarichs, Javier CSIC; García de Lacoba, Mario CSIC ORCID ; Prieto Orzanco, Alicia CSIC ORCID ; Martínez, María Jesús CSIC ORCID ; Barriuso, Jorge CSIC ORCID | artículo |
openAccess |  | 12-Oct-2017 | Zampanolide binding to tubulin indicates crosstalk of taxane site with colchicine and nucleotide sites | Field, Jessica J.; Pera, Benet CSIC; Estévez-Gallego, Juan CSIC ORCID ; Rodríguez-Salarichs, Javier CSIC; Sáez-Calvo, Gonzalo CSIC; Andreu, José Manuel CSIC ORCID ; Díaz, José Fernando CSIC ORCID | artículo |
openAccess |  | 22-Jun-2012 | Zampanolide, a potent new microtubule stabilizing agent, covalently reacts with the taxane luminal site in both tubulin alpha-beta-heterodimers and microtubules | Field, Jessica J.; Pera, Benet CSIC; Calvo, Enrique; Canales, Ángeles CSIC ORCID; Zurwerra, Didier; Trigili, Chiara CSIC; Rodríguez-Salarichs, Javier CSIC; Matesanz, Ruth CSIC ; Kanakkanthara, Arun; Wakefield, St. John; Singh, A. Jonathan; Jiménez-Barbero, Jesús CSIC ORCID; Northcote, Peter; Miller, John H.; López, Juan Antonio; Hamel, Ernest; Barasoain, Isabel CSIC ; Altmann, Karl-Heinz; Díaz, José Fernando CSIC ORCID | artículo |