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Browsing by Author Roca, Carlos

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Showing results 1 to 17 of 17
RightsPreviewIssue DateTitleAuthor(s)Type
openAccessMolecular Diversity_Gallego_2021.pdf.jpg12-Jul-2021AI in drug development: a multidisciplinary perspectiveGallego, Víctor; Naveiro, Roi; Roca, Carlos; Ríos Insua, David ; Campillo, Nuria E. CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2018Chameleon-like behavior of indolylpiperidines in complex with cholinesterases targets: Potent butyrylcholinesterase inhibitorsChierrito, Talita P. C.; Pedersoli-Mantoani, S.; Roca, Carlos; Sebastián-Pérez, Víctor; Martínez-González, Loreto CSIC ORCID CVN ; Pérez, Daniel I.; Pérez, Concepción; Canales, A.; Cañada, F. Javier CSIC ORCID ; Campillo, Nuria E. CSIC ORCID ; Carvalho, Ivone; Martínez, Ana CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2018Deciphering the Inhibition of the Neuronal Calcium Sensor 1 and the Guanine Exchange Factor Ric8a with a Small Phenothiazine Molecule for the Rational Generation of Therapeutic Synapse Function RegulatorsRoca, Carlos; Martínez-González, Loreto CSIC ORCID CVN ; Daniel-Mozo, M.; Sastre, J. CSIC; Infantes, L. CSIC ORCID; Mansilla, A.; Chaves-Sanjuan, A.; Gonzalez-Rubio, Juana M; Gil, C; Cañada, F. Javier CSIC ORCID ; Martinez, A.; Sánchez-Barrena, María José CSIC ORCID; Campillo, Nuria E. CSIC ORCID artículo
openAccess20-Oct-2017From dual binding site acetylcholinesterase inhibitors to allosteric modulators: A new avenue for disease-modifying drugs in Alzheimer's diseaseChierrito, Talita P. C.; Roca, Carlos; Requena-Trigueros, Carlos; Sebastián-Pérez, Víctor; Pérez, Concepción; Jiménez-Barbero, Jesús CSIC ORCID; Cañada, F. Javier CSIC ORCID ; Campillo, Nuria E. CSIC ORCID ; Martínez, Ana CSIC ORCID ; Carvalho, Ivoneartículo
closedAccessaccesoRestringido.pdf.jpg2019From simple quinoxalines to potent oxazolo[5,4-: F] quinoxaline inhibitors of glycogen-synthase kinase 3 (GSK3)Lassagne, F.; Duguépéroux, C.; Roca, Carlos; Pérez, Concepción; Martínez, Ana CSIC ORCID ; Baratte, B.; Robert, T.; Ruchaud, S.; Bach, S.; Erb, W.; Roisnel, T.; Mongin, F.artículo
openAccess14-Sep-2020Glycogen synthase kinase 3 (GSK-3) inhibitors: a patent update (2016–2019)Roca, Carlos; Campillo, Nuria E. CSIC ORCID artículo
openAccess28-Dec-2018Highly potent and selective aryl-1,2,3-triazolyl benzylpiperidine inhibitors toward butyrylcholinesterase in Alzheimer's diseaseDe Andrade, Peterson; Mantoani, Susimaire P.; Gonçalves Nunes, Paulo Sérgio; Roca, Carlos; Pérez, Concepción; Xavier, Danilo Jordão; Hojo, Elza Tiemi Sakamoto; Campillo, Nuria E. CSIC ORCID ; Martínez, Ana CSIC ORCID ; Carvalho, Ivoneartículo
openAccessSc. Rep.2017.pdf.jpg25-May-2017Hybridizing feature selection and feature learning approaches in QSAR modeling for drug discoveryPonzoni, Ignacio; Sebastián-Pérez, Víctor; Requena-Trigueros, Carlos; Roca, Carlos; Páez, Juan A. CSIC ORCID; Campillo, Nuria E. CSIC ORCID artículo
openAccessJEIMC_2018.pdf.jpgDec-2018Identification of new allosteric sites and modulators of AChE through computational and experimental toolsRoca, Carlos; Requena-Trigueros, Carlos; Sebastián-Pérez, Víctor; Malhotra, Sony; Radoux, Chris; Pérez, Concepción; Martínez, Ana; Páez, Juan A. CSIC ORCID; Blundell, Tom L.; Campillo, Nuria E. CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2019Indazolylketones as new multitarget cannabinoid drugsGonzález-Naranjo, Pedro CSIC ORCID; Pérez-Macías, Natalia; Pérez, Concepción; Roca, Carlos; Vaca, Gabriela; Girón, Rocío; Sánchez-Robles, E.; Martín-Fontelles, M. I.; Ceballos, María L. de CSIC ORCID; Martín-Requero, Ángeles CSIC ORCID ; Campillo, Nuria E. CSIC ORCID ; Páez, Juan A. CSIC ORCIDartículo
openAccessJCIM 2017.pdf.jpg16-Aug-2017Medicinal and biological chemistry (MBC) library: an efficient source on new hitsSebastián-Pérez, Víctor; Roca, Carlos; Awale, Mahendra; Reymond, Jean-Louis; Martínez, Ana CSIC ORCID ; Gil, Carmen ; Campillo, Nuria E. CSIC ORCID artículo
openAccessCongreso Atenas p.110.pdf.jpgSep-2019Multitarget triazoles: an innovative approach for the treatment of Alzheimer’s diseaseNozal, Vanesa; García-Rubia, Alfonso; Roca, Carlos; Pérez, Concepción; Palomo, Valle CSIC ORCID ; Martínez, Ana CSIC ORCID comunicación de congreso
openAccessNew protein-protein .pdf.jpg20-Jul-2019New protein-protein interaction modulators for the therapeutic regulation of synapse dysfunction in neurodevelopmental disorders and neurodegenerationMansilla, A.; Chaves-Sanjuan, A.; Roca, Carlos; Canal-Martín, Andrea; Daniel-Mozo, M.; Martínez-González, Loreto CSIC ORCID CVN ; Infantes, L. CSIC ORCID; Ferrús, Alberto CSIC ORCID; Martínez, A.; Pérez-Fernández, Ruth CSIC ORCID ; Campillo, Nuria E. CSIC ORCID ; Sánchez-Barrena, María José CSIC ORCIDcomunicación de congreso
openAccessScientific Reports_Ponzoni_2019.pdf.jpg24-Jun-2019QSAR classification models for predicting the activity of inhibitors of beta-secretase (BACE1) associated with Alzheimer's diseasePonzoni, Ignacio; Sebastián-Pérez, Víctor; Martínez, María J.; Roca, Carlos; de la Cruz Pérez, Carlos; Cravero, Fiorella; Vazquez, Gustavo Esteban; Páez, Juan A. CSIC ORCID; Díaz, Mónica Fátima; Campillo, Nuria E. CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2017Subtly modulating glycogen synthase kinase 3 ß: Allosteric inhibitor development and their potential for the treatment of chronic diseasesPalomo, Valle CSIC ORCID ; Pérez, Daniel I.; Roca, Carlos; Anderson, Cara; Rodríguez-Muela, Natalia; Pérez, Concepción; Morales-García, José A. CSIC ORCID; Reyes Rodríguez, Julio Alberto; Campillo, Nuria E. CSIC ORCID ; Pérez Castillo, Ana CSIC ORCID; Rubin, Lee L.; Timchenko, Lubov; Gil, Carmen ; Martínez, Ana CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2018Tau-Centric Multitarget Approach for Alzheimer's Disease: Development of First-in-Class Dual Glycogen Synthase Kinase 3β and Tau-Aggregation InhibitorsGandini, A.; Bartolini, M.; Tedesco, D.; Martínez-González, Loreto CSIC ORCID CVN ; Roca, Carlos; Campillo, Nuria E. CSIC ORCID ; Zaldívar-Díez, Josefa; Pérez, Concepción; Zuccheri, G.; Miti, A.; Feoli, A.; Castellano, S.; Petralla, S.; Monti, B.; Rossi, M.; Moda, F.; Legname, G.; Martínez, Ana; Bolognesi, Maria Lauraartículo
openAccessTesis_Carlos_Roca_Magadán_UCM.pdf.jpg2018Técnicas computacionales aplicadas al descubrimiento de neurofármacosRoca, Carlostesis doctoral