Rights | Preview | Issue Date | Title | Author(s) | Type |
openAccess |  | Mar-2013 | A structure-based design of new C2- and C13-substituted taxanes: Tubulin binding affinities and extended quantitative structure-activity relationships using comparative binding energy (COMBINE) analysis | Coderch, Claire; Tang, Yong; Klett, Javier CSIC ORCID; Zhang, Shu-En; Ma, Yung-Tao; Shaorong, Wang; Matesanz, Ruth CSIC ; Pera, Benet CSIC; Canales, Ángeles CSIC ORCID; Jiménez-Barbero, Jesús CSIC ORCID; Morreale, Antonio; Díaz, José Fernando CSIC ORCID ; Fang, Wei-shuo S.; Gago, Federico CSIC ORCID | artículo |
closedAccess |  | 14-Jun-2011 | Corrigendum: Mechanism of Action of the Cytotoxic Macrolides Amphidinolide X and J | Trigili, Chiara CSIC; Pera, Benet CSIC; Barbazanges, Marion; Cossy, Janine; Meyer, Christophe; Pineda, Oriol; Rodríguez-Escrich, Carles; Urpí, Félix; Vilarrasa, Jaume; Díaz, José Fernando CSIC ORCID ; Barasoain, Isabel CSIC | corrigenda |
openAccess |  | 22-Oct-2010 | Cpl-7, a Lysozyme Encoded by a Pneumococcal Bacteriophage with a Novel Cell Wall-Binding Motif | Bustamante, Noemí CSIC; Campillo, Nuria E. CSIC ORCID ; García, Ernesto CSIC ORCID ; Gallego, Cristina; Pera, Benet CSIC; Diakun, Gregory P.; Saiz, José L.; García, Pedro CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Menéndez, Margarita CSIC ORCID | artículo |
closedAccess |  | Jan-2012 | Cyclostreptin Derivatives Specifically Target Cellular Tubulin and Further Map the Paclitaxel Site | Calvo, Enrique; Barasoain, Isabel CSIC ; Matesanz, Ruth CSIC ; Pera, Benet CSIC; Camafeita, Emilio; Pineda, Oriol; Hamel, Ernest; Vanderwal, Christopher D.; Andreu, José Manuel CSIC ORCID ; López, Juan Antonio; Díaz, José Fernando CSIC ORCID | artículo |
openAccess |  | 1-Nov-2015 | High affinity and covalent-binding microtubule stabilizing agents show activity in chemotherapy-resistant acute myeloid leukemia cells | Pera, Benet CSIC; Calvo, María Nieves; Ambati, Srikanth; Jordi, Michel; Kahn, Alissa; Díaz, José Fernando CSIC ORCID ; Fang, Wei-Shuo; Altmann, Karl-Heinz; Cerchietti, ,Leandro; Moore, Malcolm A. S. | artículo |
closedAccess |  | 1-Jun-2011 | Mecanismo de accion de los macrolidos citotoxicos amphinolidas X y J | Trigili, Chiara CSIC; Pera, Benet CSIC; Barbazanges, Marion; Cossy, Janine; Meyer, Christophe; Pineda, Oriol; Rodríguez-Escrich, Carles; Urpí, Félix; Vilarrasa, Jaume; Díaz, José Fernando CSIC ORCID ; Barasoain, Isabel CSIC | póster de congreso |
closedAccess | | 2-May-2011 | Mechanism of Action of Cytotoxic Macrolides Amphidinolide X and J. | Trigili, Chiara CSIC; Pera, Benet CSIC; Barbazanges, Marion; Cossy, Janine; Meyer, Christophe; Pineda, Oriol; Rodríguez-Escrich, Carles; Urpí, Félix; Vilarrasa, Jaume; Díaz, José Fernando CSIC ORCID ; Barasoain, Isabel CSIC | artículo |
openAccess |  | 21-Dec-2011 | Modulation of microtubule interprotofilament interactions by modified taxanes | Matesanz, Ruth CSIC ; Rodríguez-Salarichs, Javier; Pera, Benet CSIC; Canales, Ángeles CSIC ORCID; Andreu, José Manuel CSIC ORCID ; Jiménez-Barbero, Jesús CSIC ORCID; Bras, Wim; Nogales, Aurora CSIC ORCID; Fang, Wei-Shuo; Díaz, José Fernando CSIC ORCID | artículo |
closedAccess | | 16-Aug-2010 | Molecular recognition of peloruside A by microtubules. The C24 primary alcohol is essential for biological activity. | Pera, Benet CSIC; Razzak, Mina; Trigili, Chiara CSIC; Pineda, Oriol; Canales, Ángeles CSIC ORCID; Martínez Buey, Rubén CSIC ORCID CVN; Jiménez-Barbero, Jesús CSIC ORCID; Northcote, Peter; Paterson, Ian; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID | artículo |
closedAccess |  | 16-Jul-2013 | New interfacial microtubule inhibitors of marine origin, PM050489/PM060184, with potent antitumor activity and a distinct mechanism | Pera, Benet CSIC; Barasoain, Isabel CSIC ; Pantazopoulou, Areti CSIC ORCID; Canales, Ángeles CSIC ORCID; Matesanz, Ruth CSIC ; Rodríguez-Salarichs, Javier; García-Fernández, Luis F. CSIC; Moneo, Victoria; Jiménez-Barbero, Jesús CSIC ORCID; Galmarini, Carlos M.; Cuevas, Carmen; Peñalva, Miguel Ángel CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Andreu, José Manuel CSIC ORCID | artículo |
closedAccess |  | 1-Apr-2014 | PM060184, a new tubulin binding agent with potent antitumor activity including P-glycoprotein over-expressing tumors | Martínez-Díez, Marta; Guillén-Navarro, María José; Pera, Benet CSIC; Bouchet, Benjamin Pierre; Martínez-Leal, Juan Fernando; Barasoain, Isabel CSIC ; Cuevas, Carmen; Andreu, José Manuel CSIC ORCID ; García-Fernández, Luis F. CSIC; Díaz, José Fernando CSIC ORCID ; Avilés, Pablo; Galmarini, Carlos M. | artículo |
openAccess |  | 2011 | Shotgun and targeted MS analyses pinpoint the zampanolide-tubulin interacting site | Calvo, Enrique; Field, Jessica J.; Pera, Benet CSIC; Zuwera, D.; López, Juan Antonio; Camafeita, Emilio; Barasoain, Isabel CSIC ; Altmann, Karl-Heinz; Díaz, José Fernando CSIC ORCID | póster de congreso |
closedAccess |  | Nov-2012 | Structure-activity relationships of novel substituted naphthalene diimides as anticancer agents | Milelli, Andrea; Tumiatti, Vicenzo; Micco, Marialuisa; Rosini, Michela; Zuccari, Guendalina; Raffaghello, Lizzia; Bianchi, Giovanna; Pistoia, Vito; Pistoia, Vito; Díaz, José Fernando CSIC ORCID ; Díaz, José Fernando CSIC ORCID ; Pera, Benet CSIC; Trigili, Chiara CSIC; Barasoain, Isabel CSIC ; Musetti, Caterina; Toniolo, Marianna; Sissi. Claudia; Alcaro, Stefano; Moraca, Federica; Zini, Maddalena; Stefanelli, Claudio; Minarini, Anna | artículo |
openAccess |  | 19-Jun-2014 | Taxanes with high potency inducing tubulin assembly overcome tumoural cell resistances | Matesanz, Ruth CSIC ; Trigili, Chiara CSIC; Rodríguez-Salarichs, Javier; Pera, Benet CSIC; Jiménez-Barbero, Jesús CSIC ORCID; Canales, Ángeles CSIC ORCID; Barasoain, Isabel CSIC ; Díaz, José Fernando CSIC ORCID | artículo |
openAccess |  | Nov-2011 | Thermodynamics as a Tool for the Optimization of Drug Binding, Thermodynamics - Interaction Studies - Solids, Liquids and Gases | Matesanz, Ruth CSIC ; Pera, Benet CSIC; Díaz, José Fernando CSIC ORCID | capítulo de libro |
closedAccess |  | 1-Jun-2011 | Zampanolida, un novedoso agente estabilizador de microtubulos quew se une covalentemente al sitio de paclitaxel | Field, Jessica J.; Pera, Benet CSIC; Canales, Ángeles CSIC ORCID; Zuwerra, D.; Trigili, Chiara CSIC; Kanakkanthara, Arun; Wakefield, St. John; Singh, A. Jonathan; Jiménez-Barbero, Jesús CSIC ORCID; Northcote, Peter; Miller, J.; López, Juan Antonio; Hamel, Ernest; Barasoain, Isabel CSIC ; Altmann, Karl-Heinz; Díaz, José Fernando CSIC ORCID | póster de congreso |
openAccess |  | 12-Oct-2017 | Zampanolide binding to tubulin indicates crosstalk of taxane site with colchicine and nucleotide sites | Field, Jessica J.; Pera, Benet CSIC; Estévez-Gallego, Juan CSIC ORCID ; Rodríguez-Salarichs, Javier; Sáez-Calvo, Gonzalo; Andreu, José Manuel CSIC ORCID ; Díaz, José Fernando CSIC ORCID | artículo |
openAccess |  | 22-Jun-2012 | Zampanolide, a potent new microtubule stabilizing agent, covalently reacts with the taxane luminal site in both tubulin alpha-beta-heterodimers and microtubules | Field, Jessica J.; Pera, Benet CSIC; Calvo, Enrique; Canales, Ángeles CSIC ORCID; Zurwerra, Didier; Trigili, Chiara CSIC; Rodríguez-Salarichs, Javier; Matesanz, Ruth CSIC ; Kanakkanthara, Arun; Wakefield, St. John; Singh, A. Jonathan; Jiménez-Barbero, Jesús CSIC ORCID; Northcote, Peter; Miller, John H.; López, Juan Antonio; Hamel, Ernest; Barasoain, Isabel CSIC ; Altmann, Karl-Heinz; Díaz, José Fernando CSIC ORCID | artículo |