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openAccessmolecules-28-00071.pdf.jpg2023Biginelli Reaction Synthesis of Novel Multitarget-Directed Ligands with Ca2+ Channel Blocking Ability, Cholinesterase Inhibition, Antioxidant Capacity, and Nrf2 ActivationMalek, R.; Simakov, Alexey; Davis, A.; Maj, Maciej; Bernard, P. J.; Wnorowski, Artur; Martin, Helene; Marco-Contelles, José CSIC ORCID; Chabchoub, Fakher; Dallemagne, Patrick; Rochais, C.; Józwiak, K.; Ismaili, Lhassaneartículo
pharmaceutics-16-00121.pdf.jpg17-ene-2024Design and Synthesis of Multi-Functional Ligands through Hantzsch Reaction: Targeting Ca2+ Channels, Activating Nrf2 and Possessing Cathepsin S Inhibitory, and Antioxidant PropertiesPachón-Angona, Irene; Bernard, Paul J.; Simakov, Alexey; Maj, Maciej; Jozwiak, Krzysztof; Novotna, Anna; Lemke, Carina; Gütschow, Michael; Martin, Helene; Oset-Gasque, María-Jesús; Contelles, José-Marco; Ismaili, Lhassaneartículo
closedAccessaccesoRestringido.pdf.jpg2019Multi-target 1,4-dihydropyridines showing calcium channel blockade and antioxidant capacity for Alzheimer's disease therapyMalek, R.; Maj, M.; Wnorowski, A.; Józwiak, K.; Martin, Helene; Iriepa, Isabel; Moraleda, I.; Chabchoub, Fakher; Marco-Contelles, José CSIC ORCID; Ismaili, L.artículo
closedAccessaccesoRestringido.pdf.jpg2017New (benz)imidazolopyridino tacrines as nonhepatotoxic, cholinesterase inhibitors for Alzheimer diseaseBoulebd, Houssem; Ismaili, L.; Martin, Helene; Bonet, A.; Chioua, Mourad CSIC ORCID ; Marco-Contelles, José CSIC ORCID; Belfaitah, A.artículo
openAccessJOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY.pdf.jpg2019Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer’s disease therapyDgachi, Youssef; Martin, Helene; Martin, Hélène; Malek, R; Jun, D.; Janockova, Jana; Sepsova, Vendula; Soukup, Ondrej; Iriepa, Isabel; Moraleda, Ignacio; Maalej, Enma; Carreiras, M. Carmo; Refouvelet, B.; Chabchoub, Fakher; Marco-Contelles, José CSIC ORCID; Ismaili, Lhassaneartículo
closedAccessaccesoRestringido.pdf.jpg2021Synthesis and Biological Assessment of PyrimidoTacrines as Promising Agents for Alzheimer's Disease TherapyDakhlaoui, I.; Maalej, E.; Martin, Helene; Lucht, A.; Iriepa, I.; Moraleda, I.; Marco-Contelles, José CSIC ORCID; Chabchoub, Fakher; Ismaili, L.artículo
closedAccessaccesoRestringido.pdf.jpg2019Synthesis of new ferulic/lipoic/comenic acid-melatonin hybrids as antioxidants and Nrf2 activators via Ugi reactionPachón-Angona, I.; Martin, Helene; Chhor, S.; Oset-Gasque, María Jesús; Refouvelet, B.; Marco-Contelles, José CSIC ORCID; Ismaili, L.artículo
closedAccessaccesoRestringido.pdf.jpg2019Synthesis, antioxidant and Aβ anti-aggregation properties of new ferulic, caffeic and lipoic acid derivatives obtained by the Ugi four-component reactionBenchekroun, Mohamed; Pachón-Angona, I.; Luzet, V.; Martin, Helene; Oset-Gasque, María Jesús; Marco-Contelles, José CSIC ORCID; Ismaili, L.artículo
closedAccessaccesoRestringido.pdf.jpg2017Tetrahydropyranodiquinolin-8-amines as new, non hepatotoxic, antioxidant, and acetylcholinesterase inhibitors for Alzheimer's disease therapyDgachi, Youssef; Sokolov, O.; Luzet, V.; Godyn, J.; Panek, D.; Bonet, A.; Martin, Helene; Iriepa, Isabel; Moraleda, I.; García-Iriepa, C.; Janockova, J.; Richert, L.; Soukup, O.; Malawska, B.; Chabchoub, Fakher; Marco-Contelles, José CSIC ORCID; Ismaili, L.artículo