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Browsing by Author Méndez, Juan

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openAccessBlancoL_ACancer-Associated.pdf.jpg4-Feb-2019A cancer-associated point mutation disables the steric gate of human PrimPolDíaz-Talavera, Alberto CSIC ORCID; Calvo, Patricia A.; González-Acosta, Daniel; Díaz, Marcos; Sastre-Moreno, Guillermo; Blanco-Franco, Luis; Guerra, Susana; Martínez-Jiménez, María I. CSIC ORCID ; Méndez, Juan; Blanco, Luis CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2022A truncating variant of RAD51B associated with primary ovarian insufficiency provides insights into its meiotic and somatic functionsFranca, Monica M.; Condezo, Yazmine B. CSIC ORCID; Elzaiat, Maëva; Felipe-Medina, Natalia CSIC ORCID; Sánchez-Sáez, Fernando CSIC ORCID; Muñoz, Sergio CSIC ORCID; Sainz-Urruela, Raquel; Martín-Hervás, M. Rosario; García-Valiente, R. CSIC ORCID; Sánchez-Martin, Manuel Adolfo; Astudillo, Aurora; Méndez, Juan; Llano, Elena CSIC ORCID; Veitia, Reiner A.; Mendonca, Berenice B.; Pendás, Alberto M. CSIC ORCID artículo
closedAccess1-Dec-2000An aspartic acid residue in TPR-1, a specific region of protein-priming DNA polymerases, is required for the functional interaction with primer terminalDufour, Emmanuelle; Méndez, Juan; Lázaro, José M. CSIC; Vega, Miguel de CSIC ORCID ; Blanco, Luis CSIC ORCID ; Salas, Margarita CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg3-Sep-2013Generation and analysis of a PrimPol KO mouse modelChocrón, Sandra CSIC; Reyes, Aurelio; Powell, Christopher; Mouron, Silvana; Terrados, Gloria; Guerra, Susana; Salido, Eduardo; Méndez, Juan; Holt, Ian; Blanco, Luis CSIC ORCID póster de congreso
closedAccess19-Jul-1996In VitroProtein-primed Initiation of Pneumococcal Phage Cp-1 DNA Replication Occurs at the Third 3′ Nucleotide of the Linear Template: A Stepwise Sliding-back MechanismMartín, Ana C.; Blanco, Luis CSIC ORCID ; García, Pedro CSIC ORCID ; Salas, Margarita CSIC ORCID ; Méndez, Juanartículo
openAccessPNAS-1992-Méndez-9579-83.pdf.jpg15-Oct-1992Initiation of phi 29 DNA replication occurs at the second 3' nucleotide of the linear template: a sliding-back mechanism for protein-primed DNA replicationMéndez, Juan; Blanco, Luis CSIC ORCID ; Esteban, Juan A.; Bernad, Antonio CSIC ORCID; Salas, Margarita CSIC ORCID artículo
openAccessJAEsteban_PNAS_9579.pdf.jpg15-Oct-1992Initiation of phi 29 DNA replication occurs at the second 3' nucleotide of the linear template: a sliding-back mechanism for protein-primed DNA replication.Méndez, Juan; Blanco, Luis CSIC ORCID ; Esteban, José A. CSIC ORCID; Bernad, Antonio CSIC ORCID; Salas, Margarita CSIC ORCID artículo
openAccessBlancoL_NAR_1366.pdf.jpg7-Oct-2011Molecular architecture of a multifunctional MCM complexSánchez-Berrondo, June; Mesa, Pablo; Ibarra, Arkaitz; Martínez-Jiménez, María I. CSIC ORCID ; Blanco, Luis CSIC ORCID ; Méndez, Juan; Boskovic, Jasminka; Montoya, Guillermoartículo
openAccessBlancoL_Motif WFYYofHumanPrimPol.pdf.jpg12-Jul-2021Motif WFYY of human PrimPol is crucial to stabilize the incoming 3′-nucleotide during replication fork restartCalvo, Patricia A.; Martínez-Jiménez, María I. CSIC ORCID ; Díaz, Marcos; Stojkovic, Gorazd; Kasho, Kazutoshi; Guerra, Susana; Wanrooij, Sjoerd; Méndez, Juan; Blanco, Luis CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg9-Sep-2014Mutational Analysis and Characterization of WFYY Motif in human PrimPolCalvo, Patricia A.; Díaz, Marcos ; Martínez-Jiménez, María I. CSIC ORCID ; Mourón, Silvana; Guerra, Susana; Méndez, Juan; Blanco, Luis CSIC ORCID póster de congreso
closedAccessaccesoRestringido.pdf.jpg2015NSMCE2 suppresses cancer and aging in mice independently of its SUMO ligase activityJacome, Ariana; Gutiérrez‐Martínez, Paula; Schiavoni, Federica; Tenaglia, Enrico; Martínez, Paula; Rodríguez‐Acebes, Sara; Lecona, Emilio CSIC ORCID; Murga, Matilde; Méndez, Juan; Blasco, María A.; Fernández-Capetillo, Óscarartículo
openAccessPARP1_Fütterer_Art_2024.pdf.jpgJan-2024PARP1, DIDO3, and DHX9 Proteins Mutually Interact in Mouse Fibroblasts, with Effects on DNA Replication Dynamics, Senescence, and Oncogenic TransformationFütterer, Agnes; Rodríguez-Acebes, Sara; Méndez, Juan; Gutiérrez, Julio; Martínez-A, Carlos CSIC ORCIDartículo
openAccess1-s2.0-S1097276516303343-main.pdf.jpg1-Sep-2016POLD3 Is Haploinsufficient for DNA Replication in MiceMurga, Matilde; Lecona, Emilio CSIC ORCID; Kamileri, Irene; Díaz, Marcos; Lugli, Natalia; Sotiriou, Sotirios K.; Anton, Marta E.; Méndez, Juan; Halazonetis, Thanos D.; Fernández-Capetillo, Óscarartículo
closedAccess10-Feb-1995Primer-terminus stabilizatión at the ø29 DNA polymerase active site: mutational analysis of conserved motif KxYBlasco, María A.; Méndez, Juan; Lázaro, José M. CSIC; Blanco, Luis CSIC ORCID ; Salas, Margarita CSIC ORCID artículo
closedAccess25-Nov-1994Primer-terminus stabilization at the ø29 DNA polymerase active site: mutational analysis of conserved motif Tx2GRMéndez, Juan; Blanco, Luis CSIC ORCID ; Lázaro, José M. CSIC; Salas, Margarita CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg3-Mar-2013PrimPol, a new human DNA primase/polymerase, is involved in translesion synthesis and recovery of stalled forks during nuclear DNA replicationMéndez, Juan; Mourón, Silvana; Rodríguez-Acebes, Sara; García-Gómez, Sara CSIC; Martínez-Jiménez, María I. CSIC ORCID ; Chocrón, Sandra CSIC; Blanco, Luis CSIC ORCID póster de congreso
openAccessBlancoL_PrimPol-mediatedRepriming.pdf.jpg4-May-2021PrimPol-mediated repriming facilitates replication traverse of DNA interstrand crosslinksGonzález-Acosta, Daniel; Blanco-Romero, Elena; Ubieto-Capella, Patricia; Mutreja, Karun; Míguez, Samuel; Llanos, Susana CSIC ORCID; García, Fernando; Muñoz, Javier ; Blanco, Luis CSIC ORCID ; Lopes, Massimo; Méndez, Juanartículo
closedAccess1997Protein-primed DNA replication: A transition between two modes of priming by a unique DNA polymeraseMéndez, Juan; Blanco, Luis CSIC ORCID ; Salas, Margarita CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2013Repriming of DNA synthesis at stalled replication forks by human PrimPolMourón, Silvana; Rodríguez-Acebes, Sara; Martínez-Jiménez, María I. CSIC ORCID ; García-Gómez, Sara CSIC; Chocrón, Sandra CSIC; Blanco Dávila, Luis; Méndez, Juanartículo
closedAccessaccesoRestringido.pdf.jpg19-Oct-2017Shortage of dNTPs underlies altered replication dynamics and DNA breakage in the absence of the APC/C cofactor Cdh1Garzón, J.; Rodríguez, R.; Kong, Z.; Chabes, A.; Rodríguez-Acebes, Sara; Méndez, Juan; Moreno, Sergio CSIC ORCID; García-Higuera, Irene CSIC ORCIDartículo