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Browsing by Author Lucas, José Javier

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closedAccessaccesoRestringido.pdf.jpg2007A mouse model to study tau pathology related with tau phosphorylation and assemblyEngel, Tobías; Lucas, José Javier CSIC ORCID; Hernández, Félix; Ávila, Jesús CSIC ORCID artículo
openAccessA_Neuroprotective_Role_Simón_ComCong2021.pdf.jpg21-Sep-2021A Neuroprotective Role of Protein Kinase D in Huntington ́s DiseaseSimón-García, Ana; Sebastián-Serrano, Álvaro; Santos-Galindo, María CSIC ORCID; Campanero, Miguel R. CSIC ORCID; Lucas, José Javier CSIC ORCID; Iglesias, Teresa CSIC ORCID comunicación de congreso
closedAccessaccesoRestringido.pdf.jpg2012Age-dependent decline of motor neocortex but not hippocampal performance in heterozygous BDNF mice correlates with a decrease of cortical PSD-95 but an increase of hippocampal TrkB levelsCarretón, Olga; Giralt, Albert; Torres-Peraza, Jesús F. CSIC; Brito, Verónica; Lucas, José Javier CSIC ORCID; Ginés, Silvia; Canals, Josep María; Alberch, Jordiartículo
closedAccessaccesoRestringido.pdf.jpg2004Assembly in vitro of tau protein and its implications in Alzheimers diseaseÁvila, Jesús CSIC ORCID ; Pérez, Mar; Lucas, José Javier CSIC ORCID; Gómez Ramos, Alberto; Santa María, Ismael CSIC; Moreno, Francisco J.; Smith, Mark A.; Perry, George; Hernández, Félixartículo
closedAccessaccesoRestringido.pdf.jpg15-Aug-2018Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicingParras, Alberto; Anta, Héctor; Santos-Galindo, María CSIC ORCID; Swarup, Vivek; Elorza, Ainara; Nieto-González, J.; Picó, Sara; Hernández, Ivó H.; Díaz-Hernández, Juan I.; Belloc, Eulàlia; Rodolosse, Annie; Parikshak, Neelroop N.; Peñagarikano, Olga; Fernández-Chacón, Rafael; Irimia, Manuel; Navarro, Pilar CSIC; Geschwind, Daniel H.; Méndez, Raúl CSIC ORCID; Lucas, José Javier CSIC ORCIDartículo
openAccessCell Death & Disease 2018.pdf.jpg20-Sep-2018Bi-directional genetic modulation of GSK-3β exacerbates hippocampal neuropathology in experimental status epilepticusEngel, Tobías; Gómez-Sintes, Raquel CSIC ORCID ; Alves, Mariana; Jiménez-Mateos, Eva María; Fernández-Nogales, Marta; Sanz-Rodríguez, Amaya; Morgan, James; Beamer, Edward; Rodríguez-Matellán, Alberto G.; Dunleavy, Mark; Takanori, Sano; Ávila, Jesús CSIC ORCID ; Medina, Miguel CSIC ORCID; Hernández Pérez, Félix; Lucas, José Javier CSIC ORCID; Henshall, David C.artículo
openAccessbiochemicabrain.pdf.jpg2004Biochemical, ultrastructural, and reversibility studies on Huntingtin filaments isolated from mouse and human brainDíaz-Hernández, Miguel; Moreno-Herrero, Fernando; Gómez-Ramos, Pilar; Morán, María A.; Ferrer, Isidro; Baró, Arturo M.; Ávila, Jesús CSIC ORCID ; Hernández, Félix; Lucas, José Javier CSIC ORCIDartículo
openAccessJAEsteban_JAD_325.pdf.jpg2010Centro de Biologia Molecular “Severo Ochoa”: A center for basic research into Alzheimer’s diseaseÁvila, Jesús CSIC ORCID ; Hernández, Félix; Wandosell, Francisco CSIC ORCID ; Lucas, José Javier CSIC ORCID; Esteban, José A. CSIC ORCID; Ledesma, M. Dolores CSIC ORCID; Bullido, María Jesús CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg2013CHOP regulates the p53-MDM2 axis and is required for neuronal survival after seizuresEngel, Tobías; Lucas, José Javier CSIC ORCID; Henshall, D. C.artículo
closedAccessaccesoRestringido.pdf.jpg2006Chronic lithium administration to FTDP-17 tau and GSK-3β overexpressing mice prevents tau hyperphosphorylation and neurofibrillary tangle formation, but pre-formed neurofibrillary tangles do not revertEngel, Tobías; Goñi-Oliver, Paloma CSIC; Lucas, José Javier CSIC ORCID; Ávila, Jesús CSIC ORCID ; Hernández, Félixartículo
openAccessWO2021058847A1.pdf.jpg1-Apr-2021Combined use of biotin and thiamine in the treatment of Huntington's diseaseLucas, José Javier CSIC ORCID; Picó, Sara; Parras, Alberto; Santos-Galindo, María CSIC ORCIDsolicitud de patente
closedAccessaccesoRestringido.pdf.jpg2006Cooexpression of FTDP-17 tau and GSK-3β in transgenic mice induce tau polymerization and neurodegenerationEngel, Tobías; Lucas, José Javier CSIC ORCID; Gómez-Ramos, Pilar; Morán, María A.; Ávila, Jesús CSIC ORCID ; Hernández, Félixartículo
closedAccess2021CPEB alteration and aberrant transcriptome-polyadenylation lead to a treatable SLC19A3 deficiency in Huntington¿s diseasePicó, Sara; Parras, Alberto; Santos-Galindo, María CSIC ORCID; Pose-Utrilla, Julia; Castro, Margarita; Fraga, Enrique; Ivó, H. Hernandez; Elorza, Ainara; Anta, Héctor; Wang, Nan; Martí-Sánchez, Laura; Belloc, Eulàlia; García-Esparcia, Paula; Garrido, Juan J.; Ferrer, Isidro; Macías-García, Daniel; Mir, Pablo CSIC ORCID; Artuch, Rafael; Pérez, Belén; Hernández, Félix; Navarro, Pilar CSIC; López-Sendón, José Luis; Iglesias, Teresa CSIC ORCID; Yang, Willian; Méndez, Raúl CSIC ORCID; Lucas, José Javier CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg29-Sep-2021CPEB alteration and aberrant transcriptome-polyadenylation lead to a treatable SLC19A3 deficiency in Huntington’s diseasePicó, Sara; Parras, Alberto; Santos-Galindo, María CSIC ORCID; Pose-Utrilla, Julia; Castro, Margarita; Fraga, Enrique; Hernández, Ivó H.; Elorza, Ainara; Anta, Héctor; Wang, Nan; Martí-Sánchez, Laura; Belloc, Eulàlia; García-Esparcia, Paula; Garrido, Juan J.; Ferrer, Isidro; Macías-García, Daniel; Mir, Pablo CSIC ORCID; Artuch, Rafael; Pérez, Belén; Hernández, Félix; Navarro, Pilar CSIC; López-Sendón, José Luis; Iglesias, Teresa CSIC ORCID ; Yang, X. William; Méndez, Raúl CSIC ORCID; Lucas, José Javier CSIC ORCIDartículo
openAccessLucas JJ Decreased gycogen.pdf.jpg11-Jun-2015Decreased glycogen synthase kinase-3 levels and activity contribute to Huntington's diseaseFernández-Nogales, Marta; Hernández Pérez, Félix; Miguez, Andrés; Alberch, Jordi; Ginés, Silvia; Pérez-Navarro, Esther; Lucas, José Javier CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg2001Decreased nuclear β-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3β conditional transgenic miceLucas, José Javier CSIC ORCID; Hernández, Félix; Gómez-Ramos, Pilar; Morán, María A.; Hen, René; Ávila, Jesús CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpgJan-2019Differential regulation of Kidins220 isoforms in Huntington's diseaseSebastián-Serrano, Álvaro; Simón-García, Ana; Belmonte-Alfaro, Alicia; Pose-Utrilla, Julia; Santos-Galindo, María CSIC ORCID; Puerto, Ana del; García-Guerra, Lucía; Hernández, Ivó H.; Schiavo, Giampietro; Campanero, Miguel R. CSIC ORCID; Lucas, José Javier CSIC ORCID; Iglesias, Teresa CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg2004Enhaced induction of the immunoproteasome by interferon gamma in neurons expressing mutant huntingtinDíaz-Hernández, Miguel; Martín-Aparicio, Ester; Ávila, Jesús CSIC ORCID ; Hernández, Félix; Lucas, José Javier CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg2001FTDP-17 mutations in tau transgenic mice provoke lysosomal abnormalities and tau filaments in forebrainLim, Filip CSIC ORCID; Hernández, Félix; Lucas, José Javier CSIC ORCID; Gómez-Ramos, Pilar; Morán, María A.; Ávila, Jesús CSIC ORCID artículo
openAccessfullkinase3.pdf.jpg2006Full reversal of Alzheimer's disease-like phenotype in a mouse model with conditional overexpression of glycogen synthase kinase-3Engel, Tobías; Hernández, Félix; Ávila, Jesús CSIC ORCID ; Lucas, José Javier CSIC ORCIDartículo