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Browsing by Author Ledesma, M. Dolores

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closedAccessaccesoRestringido.pdf.jpgDec-2016A diet enriched with plant sterols prevents the memory impairment induced by cholesterol loss in senescence-accelerated micePérez-Cañamás, Azucena; Sarroca, Sara CSIC; Melero-Jerez, Carolina CSIC ORCID; Porquet, David CSIC; Sansa, Joan; Knafo, Shira CSIC ORCID; Esteban, José A. CSIC ORCID; Sanfeliu, Coral CSIC ORCID; Ledesma, M. Dolores CSIC ORCIDartículo
openAccessÁvilaJ_Adeno-associatedViral.pdf.jpg21-Aug-2019Adeno-associated viral vector serotype 9-based gene therapy for Niemann-Pick disease type ASamaranch, Lluís; Pérez-Cañamás, Azucena; Soto-Huelin, Beatriz; Sudhakar, Vivek; Jurado-Arjona, Jerónimo CSIC; Hadaczek, Piotr; Ávila, Jesús CSIC ORCID ; Bringas, John R.; Casas, Josefina CSIC ORCID ; Chen, Haifeng; He, Xingxuan; Schuchman, Edward Howard; Cheng, Seng H.; Forsayeth, John; Bankiewicz, Krystof S.; Ledesma, M. Dolores CSIC ORCIDartículo
openAccessAAV9-based gene therapy for Niemann-Pick disease type A.pdf.jpg21-Aug-2019Adeno-associated viral vector serotype 9-based gene therapy for Niemann-Pick disease type ASamaranch, Lluís; Pérez-Cañamás, Azucena; Soto-Huelin, Beatriz; Sudhakar, Vivek; Jurado-Arjona, Jerónimo CSIC; Hadaczek, Piotr; Ávila, Jesús CSIC ORCID ; Bringas, John R.; Casas, Josefina CSIC ORCID ; Chen, Haifeng; He, Xingxuan; Schuchman, Edward Howard; Cheng, Seng H.; Forsayeth, John R.; Bankiewicz, Krystof S.; Ledesma, M. Dolores CSIC ORCIDartículo
openAccessanalysfilam.pdf.jpg1994Analysis of microtubule-associated protein tau glycation in paired helical filamentsLedesma, M. Dolores CSIC ORCID; Bonay, Pedro CSIC; Colaço, Camilo; Ávila, Jesús CSIC ORCID artículo
openAccessapolidisea.pdf.jpg2020Apolipoprotein D-mediated preservation of lysosomal function promotes cell survival and delays motor impairment in Niemann-Pick type A diseasePascua-Maestro, Raquel CSIC ORCID; Corraliza-Gómez, Miriam; Fadrique-Rojo, Cristian; Ledesma, M. Dolores CSIC ORCID; Schuchman, Edward H.; Sánchez, Diego CSIC ORCID CVN; Ganfornina, M. D. CSIC ORCID CVNartículo
openAccessVOLUMEN 5.pdf.jpg2020Brain, Mind and BehaviourHerrera, Eloisa CSIC ORCID ; Esteban, José A. CSIC ORCID; Martí, Elisa CSIC ORCID ; Martínez-Morales, Juan Ramón CSIC ORCID; Menéndez de la Prida, Liset CSIC ORCID ; Reig, Ramón CSIC ORCID; Canals, Santiago CSIC ORCID; Bartumeus, Frederic CSIC ORCID ; Ledesma, M. Dolores CSIC ORCID; Bortolozzi, Analía CSIC ORCID; Planas, Anna M. CSIC ORCID; Moreno, Juan Camilo CSIC ORCID ; Sanz Herranz, Yolanda CSIC ORCID; López-Atalaya, José P. CSIC ORCID; Agustí, Ana CSIC ORCID; Dotti, Carlos G. CSIC ORCID; Rodríguez Rodríguez, Vicente CSIC ORCID ; Serrano-Saiz, Esther CSIC ORCID ; Santesmases, María Jesús CSIC ORCID capítulo de libro
openAccessJAEsteban_JAD_325.pdf.jpg2010Centro de Biologia Molecular “Severo Ochoa”: A center for basic research into Alzheimer’s diseaseÁvila, Jesús CSIC ORCID ; Hernández, Félix; Wandosell, Francisco CSIC ORCID ; Lucas, José Javier CSIC ORCID; Esteban, José A. CSIC ORCID; Ledesma, M. Dolores CSIC ORCID; Bullido, María Jesús CSIC ORCIDartículo
openAccessAnalia - Brain, Mind and Behaviour 89-95 (2021) - CHALLENGE 6 Understanding Mental Disorders.pdf.jpg2021CHALLENGE 6: Exposing the roots of mental disordersLedesma, M. Dolores CSIC ORCID; Bortolozzi, Analía CSIC ORCID; Lucas, J.; Barco, Ángel CSIC ORCID ; Pérez-Otaño, Isabel CSIC ORCID; Perea, Gertrudis CSIC ORCID; Álvarez-Dolado, Manuel CSIC ORCID CVN; Adell, Albert CSIC ORCID ; López-Giménez, Juan F. CSIC ORCID; Rodríguez-Franco, María Isabel CSIC ORCID ; Huertas, Rafael; Crespo-Facorro, Benedicto CSIC ORCID CVN; Vieta, Eduardcapítulo de libro
closedAccessaccesoRestringido.pdf.jpg1994Dephosphorylation of tau protein from Alzheimer's disease patientsSzücs, Kornélia; Ledesma, M. Dolores CSIC ORCID; Dombrádi, Viktor; Gergely, Pál; Ávila, Jesús CSIC ORCID ; Friedrich, Peterartículo
openAccess1-s2.0-S0969996123001559-main.pdf.jpg15-Jun-2023Ellagic acid and its metabolites urolithins A/B ameliorate most common disease phenotypes in cellular and mouse models for lysosomal storage disorders by enhancing extracellular vesicle secretionSoto-Huelin, Beatriz; Babiy, Bohdan; Pastor, Oscar; Díaz-García, Mario; Toledano-Zaragoza, Ana; Frutos, María Dolores; Espín de Gea, Juan Carlos CSIC ORCID ; Tomás Barberán, Francisco CSIC ORCID; Busto, Rebeca; Ledesma, M. Dolores CSIC ORCIDartículo
openAccessimplicadisea.pdf.jpg1992Implication of brain cdc2 and MAP2 kinases in the phosphorylation of tau protein in Alzheimer's diseaseLedesma, M. Dolores CSIC ORCID; Correas, Isabel CSIC ORCID; Ávila, Jesús CSIC ORCID ; Díaz-Nido, Javier CSIC ORCIDartículo
openAccess2015Improvement of biochemical and behavioral defects in the Niemann-Pick type A mouse by intraventricular infusion of MARCKSTrovó, Laura; Stroobants, Stijn; D'Hooge, Rudi; Ledesma, M. Dolores CSIC ORCID; Dotti, Carlos G. CSIC ORCIDartículo
openAccessLedesmaMD_InhibitionofFattyAcid.pdf.jpg14-Sep-2020Inhibition of fatty acid amide hydrolase prevents pathology in neurovisceral acid sphingomyelinase deficiency by rescuing defective endocannabinoid signalingBartoll, Adrián CSIC; Toledano-Zaragoza, Ana; Casas, Josefina CSIC ORCID ; Guzmán, Manuel; Schchman, Edward H; Ledesma, M. Dolores CSIC ORCIDartículo
openAccessemmm.201911776.pdf.jpg2020Inhibition of fatty acid amide hydrolase prevents pathology in neurovisceral acid sphingomyelinase deficiency by rescuing defective endocannabinoid signaling.Bartoll, Adrián CSIC; Toledano‐Zaragoza, Ana; Casas, Josefina CSIC ORCID ; Guzmán, Manuel; Schuchman, Edward H.; Ledesma, M. Dolores CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg1995Isolation of a phosphorylated soluble Tau fraction from Alzheimer's disease brainLedesma, M. Dolores CSIC ORCID; Ávila, Jesús CSIC ORCID ; Correas, Isabel CSIC ORCIDartículo
openAccessbook_1616_com.pdf.jpg2022Libro Blanco Volumen 5: Cerebro, mente y comportamientoMarco de Lucas, Jesús Eugenio; Moreno-Arribas, M. Victoria CSIC ORCID ; Herrera, Eloisa CSIC ORCID ; Esteban, José A. CSIC ORCID; Martí, Elisa CSIC ORCID ; Martínez-Morales, Juan Ramón CSIC ORCID; Menéndez de la Prida, Liset CSIC ORCID ; Reig, Ramón CSIC ORCID; Canals, Santiago CSIC ORCID; Bartumeus, Frederic CSIC ORCID ; Serrano-Saiz, Esther CSIC ORCID ; Santesmases, María Jesús CSIC ORCID ; Sanz Herranz, Yolanda CSIC ORCID; López-Atalaya, José P. CSIC ORCID; Agustí, Ana CSIC ORCID; Ledesma, M. Dolores CSIC ORCID; Bortolozzi, Analía CSIC ORCID; Dotti, Carlos G. CSIC ORCID; Rodríguez Rodríguez, Vicente CSIC ORCID ; Planas, Anna M. CSIC ORCID; Moreno, Juan Camilo CSIC ORCID libro
closedAccessaccesoRestringido.pdf.jpg2012Lipid changes in the aged brain: Effect on synaptic function and neuronal survivalLedesma, M. Dolores CSIC ORCID; Martín, Mauricio G. CSIC ORCID; Dotti, Carlos G. CSIC ORCIDartículo
openAccessLedesmeMD_LipidDymanicsatDentriticSpines.pdf.jpg8-Aug-2014Lipid dynamics at dendritic spinesDotti, Carlos G. CSIC ORCID; Esteban, José A. CSIC ORCID; Ledesma, M. Dolores CSIC ORCIDartículo
openAccessARR 2016.pdf.jpgDec-2016Lysosomal cell death mechanisms in agingGómez-Sintes, Raquel CSIC ORCID ; Ledesma, M. Dolores CSIC ORCID; Boya, Patricia CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2000Microtubule-associated protein-2 located in growth regions of rat hippocampal neurons is highly phosphorylated at its proline-rich regionSánchez Martin, C.; Ledesma, M. Dolores CSIC ORCID; Dotti, Carlos G. CSIC ORCID; Ávila, Jesús CSIC ORCID artículo