Rights | Preview | Issue Date | Title | Author(s) | Type |
closedAccess |  | 2012 | Benzothiazepine CGP37157 and its isosteric 2′-ethyl analogue provide neuroprotection and block cell calcium entry | González-Lafuente, Laura; Egea, Javier; León, Rafael; Martínez-Sanz, F. J.; Monjas, Leticia ; Pérez, Concepción; Merino, Cristina; García-De Diego. Antonio M.; Rodríguez-Franco, María Isabel ; García, Antonio G.; Villarroya, Mercedes; Lopez, Manuela G.; Ríos, Cristóbal de los | artículo |
openAccess |  | 2017 | Enzymatic and solid-phase synthesis of new donepezil-based L- and D-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia | Monjas, Leticia ; Arce, Mariana P. ; León, Rafael; Egea, Javier; Pérez, Concepción; Villarroya, Mercedes; Lopez, Manuela G.; Gil, Carmen ; Conde, Santiago; Rodríguez-Franco, María Isabel  | artículo |
openAccess |  | Sep-2020 | Geochemical behavior of rare earth elements in acid drainages: Modeling achievements and limitations | Lozano, Alba; Ayora, Carlos ; Macías, Francisco; Gimeno, María José; León, Rafael; Auqué, Luis | artículo |
closedAccess |  | 21-May-2020 | Impact of KPC Production and High-Level Meropenem Resistance on All-Cause Mortality of Ventilator-Associated Pneumonia in Association with Klebsiella pneumoniae | Rivera-Espinar, Francisco; Machuca, Isabel; Tejero, Rocío; Rodríguez, Jorge; Mula, Ana; Marfil-Pérez, Eduardo; Cano, Ángela; Gutiérrez-Gutiérrez, Belén; Rodríguez, Marina; Pozo, Juan Carlos; Fuente, Carmen de la; Rodríguez-Baño, Jesús; Martínez-Martínez, Luis; León, Rafael; Torre-Cisneros, Julián | artículo |
closedAccess |  | 2017 | Mortality Associated with Bacteremia Due to Colistin-Resistant Klebsiella pneumoniae with High-Level Meropenem Resistance: Importance of Combination Therapy without Colistin and Carbapenems | Machuca, Isabel; Gutiérrez-Gutiérrez, Belén; Gracia-Ahufinger, Irene; Rivera-Espinar, Francisco; Cano, Ángela; Guzmán-Puche, Julia; Pérez-Nadales, Elena; Natera, Clara; Rodríguez, Marina; León, Rafael; Castón, Juan J.; Rodríguez-López, Fernando; Rodríguez-Baño, Jesús; Torre-Cisneros, Julián | artículo |
openAccess |  | 17-Jul-2020 | Multitarget Virtual Screening for Drug Repurposing in COVID19 | Sorzano, Carlos Óscar S.; Crisman, Enrique; Carazo, José M.; León, Rafael | artículo |
closedAccess | | 2011 | N-Acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer’s disease | González Muñoz, Gema C.; Arce, Mariana P. ; López, Beatriz; López, Beatriz; Romero, Alejandro ; del Barrio, Laura; Martín de Saavedra, María Dolores; Egea, Javier; León, Rafael; Villarroya, Mercedes; López, Manuela G.; García, Antonio G.; Conde, Santiago ; Rodríguez-Franco, María Isabel  | artículo |
closedAccess |  | 2013 | Novel multitarget ligand ITH33/IQM9.21 provides neuroprotection in in vitro and in vivo models related to brain ischemia | Lorrio, Silvia; Gómez-Rangel, Vanessa; Negredo, Pilar; Egea, Javier; León, Rafael; Romero, Alejandro ; Dal-Cim, Tharine.; Villarroya, Mercedes; Rodríguez-Franco, María Isabel ; Conde, Santiago ; Arce, Mariana P. ; Roda, José María; García, Antonio G.; López, Manuela G. | artículo |
closedAccess |  | 2017 | Novel sulfoglycolipid IG20 causes neuroprotection by activating the phase II antioxidant response in rat hippocampal slices | Punzón, Eva; García-Alvarado, F.; Maroto, Marcos; Fernández-Mendívil, Cristina; Michalska, P.; García-Álvarez, Isabel; Arranz-Tagarro, J. A.; Buendía, Izaskun; López, M. G.; León, Rafael; Gandía, Luis; Fernández-Mayoralas, Alfonso ; García, Antonio G. | artículo |
openAccess |  | 3-Jul-2019 | Nrf2 Plays a Protective Role Against Intravascular Hemolysis-Mediated Acute Kidney Injury | Rubio-Navarro, Alfonso; Vázquez-Carballo, Cristina; Guerrero-Hue, Melania; García-Caballero, Cristina; Herencia, Carmen; Gutiérrez, Eduardo; Yuste, Claudia; Sevillano, Ángel; Praga, Manuel; Egea, Javier; Cannata, Pablo; Cortegano, Isabel ; Andrés, Belén de; Gaspar, María Luisa; Cadenas, Susana; Michalska, Patrycja; León, Rafael; Ortiz, Alberto; Egido, Jesús; Moreno, Juan Antonio | artículo |
closedAccess |  | 2013 | Recent advances in the multitarget-directed ligands approach for the treatment of Alzheimer's disease | León, Rafael; Garcia, Antonio G.; Marco-Contelles, José  | artículo |
closedAccess |  | 2016 | The Antioxidant Additive Approach for Alzheimer's Disease Therapy: New Ferulic (Lipoic) Acid Plus Melatonin Modified Tacrines as Cholinesterases Inhibitors, Direct Antioxidants, and Nuclear Factor (Erythroid-Derived 2)-Like 2 Activators | Benchekroun, M.; Romero, A. ; Egea, Javier; León, Rafael; Michalska, P.; Buendía, I.; Jimeno, M. Luisa ; Jun, D.; Janockova, J.; Sepsova, V.; Soukup, O.; Bautista-Aguilera, Óscar M.; Refouvelet, B.; Ouari, O.; Marco-Contelles, José ; Ismaili, L. | artículo |
openAccess |  | 2020 | When It Comes to an End: Oxidative Stress Crosstalk with Protein Aggregation and Neuroinflammation Induce Neurodegeneration | Michalska, P.; León, Rafael | artículo |