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Browsing by Author Iriepa, Isabel

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closedAccessaccesoRestringido.pdf.jpg2020Automated Synthesis of New QuinoxalinetacrinesBautista-Aguilera, Óscar M.; Ismaili, L.; Chioua, Mourad CSIC ORCID ; Iriepa, Isabel; Martínez-Grau, Angeles; Beadle, C. D.; Vetman, T.; López-Muñoz, Francisco; Marco-Contelles, José CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg2018Contilisant, a Tetratarget Small Molecule for Alzheimer's Disease Therapy Combining Cholinesterase, Monoamine Oxidase Inhibition, and H3R Antagonism with S1R Agonism ProfileBautista-Aguilera, Óscar M.; Budni, J.; Mina, F.; Medeiros, E. B.; Deuther-Conrad, W.; Entrena, J. M.; Moraleda, I.; Iriepa, Isabel; López-Muñoz, F.; Marco-Contelles, José CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg2014Design, synthesis, pharmacological evaluation, QSAR analysis, molecular modeling and ADMET of novel donepezil-indolyl hybrids as multipotent cholinesterase/monoamine oxidase inhibitors for the potential treatment of Alzheimer's diseaseBautista-Aguilera, Óscar M.; Esteban, Gerard; Bolea, Irene; Nikolic, Katarina; Agbaba, Danica; Moraleda, Ignacio; Iriepa, Isabel; Samadi, Abdelouahid CSIC ORCID; Soriano, Elena CSIC; Unzeta, Mercedes; Marco-Contelles, José CSIC ORCIDartículo
openAccessJOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY.pdf.jpg2019Donepezil + chromone + melatonin hybrids as promising agents for Alzheimer’s disease therapyPachón-Angona, I.; Refouvelet, B.; Andrýs, R.; Martin, H.; Luzet, V.; Iriepa, Isabel; Moraleda, I.; Diez-Iriepa, Daniel; Oset-Gasque, M. J.; Marco-Contelles, José CSIC ORCID; Musilek, K.; Ismaili, L.artículo
closedAccessaccesoRestringido.pdf.jpg2014Donepezil + propargylamine + 8-hydroxyquinoline hybrids as new multifunctional metal-chelators, ChE and MAO inhibitors for the potential treatment of Alzheimer's diseaseWang, L.; Esteban, Gerard; Ojima, Masaki; Bautista-Aguilera, Óscar M.; Inokuchi, Tsutomu; Moraleda, Ignacio; Iriepa, Isabel; Samadi, Abdelouahid CSIC ORCID; Youdim, Moussa B. H.; Romero, Alejandro CSIC ORCID; Soriano, Elena CSIC; Herrero, Raquel; Fernández Fernández, Ana Patricia CSIC ORCID; Martínez-Murillo, Ricardo CSIC ORCID; Marco-Contelles, José CSIC ORCID; Unzeta, Mercedesartículo
openAccessmolecules-21-00400.pdf.jpg24-Mar-2016Imidazopyranotacrines as Non-Hepatotoxic, Selective Acetylcholinesterase Inhibitors, and Antioxidant Agents for Alzheimer's Disease TherapyBoulebd, Houssem; Ismaili, L.; Bartolini, Manuela; Bouraiou, Abdelmalek; Andrisano, Vincenza; Martin, Hélène; Bonet, Alexandre; Moraleda, Ignacio; Iriepa, Isabel; Chioua, Mourad CSIC ORCID ; Belfaitah, Ali; Marco-Contelles, José CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg1-Jun-2003Infrared analysis and molecular structure of α-aminonitriles derived from 1-azaadamantan-4-oneIriepa, Isabel; Villasante, Francisco Javier; Morreale, Antonio; Gálvez-Ruano, Enrique; Bellanato, Juana CSIC ; Cano, Félix H.artículo
closedAccessaccesoRestringido.pdf.jpg2019Multi-target 1,4-dihydropyridines showing calcium channel blockade and antioxidant capacity for Alzheimer's disease therapyMalek, R.; Maj, M.; Wnorowski, A.; Józwiak, K.; Martin, H.; Iriepa, Isabel; Moraleda, I.; Chabchoub, Fakher; Marco-Contelles, José CSIC ORCID; Ismaili, L.artículo
openAccessDrug Design, Development and Therapy.pdf.jpg2014Multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer’s disease: Design, synthesis, biochemical evaluation, ADMET, molecular modeling, and QSAR analysis of novel donepezil-pyridyl hybridsBautista-Aguilera, Óscar M.; Esteban, Gerard; Chioua, Mourad CSIC ORCID ; Nikolic, Katarina; Agbaba, Danica; Moraleda, Ignacio; Iriepa, Isabel; Soriano, Elena CSIC; Samadi, Abdelouahid CSIC ORCID; Unzeta, Mercedes; Marco-Contelles, José CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg2017Multitarget-Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3R Antagonism for Neurodegenerative DiseasesBautista-Aguilera, Óscar M.; Hagenow, S.; Palomino-Antolin, A.; Farré-Alins, V.; Ismaili, L.; Joffrin, P. L.; Jimeno, M. Luisa; Soukup, O.; Janockova, Jana; Kalinowski, A.; Proschak, E.; Iriepa, Isabel; Moraleda, I.; Schwed, J. S.; Romero Martínez, Alejandro; López-Muñoz, Francisco; Chioua, Mourad CSIC ORCID ; Egea, Javier; Ramsay, R. R.; Marco-Contelles, José CSIC ORCID; Stark, H.artículo
closedAccessaccesoRestringido.pdf.jpg2019Novel Quinolylnitrones Combining Neuroprotective and Antioxidant PropertiesChioua, Mourad CSIC ORCID ; Salgado-Ramos, M.; Diez-Iriepa, Daniel; Escobar-Peso, A.; Iriepa, Isabel; Hadjipavlou-Litina, Dimitra; Martínez-Alonso, Emma; Alcázar, Alberto; Marco-Contelles, José CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg2016Potent anticholinesterasic and neuroprotective pyranotacrines as inhibitors of beta-amyloid aggregation, oxidative stress and tau-phosphorylation for Alzheimer's diseaseGarcía-Font, Nuria; Hayour, H.; Belfaitah, A.; Pedraz, J.; Moraleda, I.; Iriepa, Isabel; Bouraiou, A.; Chioua, Mourad CSIC ORCID ; Marco-Contelles, José CSIC ORCID; Oset-Gasque, M. J.artículo
closedAccessaccesoRestringido.pdf.jpg2015Pyranopyrazolotacrines as nonneurotoxic, Aβ-anti-aggregating and neuroprotective agents for Alzheimer's diseaseChioua, Mourad CSIC ORCID ; Pérez-Peña, Javier; García-Font, Nuria; Moraleda, Ignacio; Iriepa, Isabel; Soriano, Elena CSIC; Marco-Contelles, José CSIC ORCID; Oset-Gasque, María Jesúsartículo
openAccessmolecules-24-01503.pdf.jpg17-Apr-2019QuinoxalineTacrine QT78, a Cholinesterase Inhibitor as a Potential Ligand for Alzheimer’s Disease TherapyRamos, Eva; Palomino-Antolín, Alejandra; Bartolini, Manuela; Iriepa, Isabel; Moraleda, Ignacio; Diez-Iriepa, Daniel; Samadi, Abdelouahid CSIC ORCID; Cortina, Carol V.; Chioua, Mourad CSIC ORCID ; Egea, Javier; Romero, Alejandro CSIC ORCID; Marco-Contelles, José CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg28-May-2001Spectroscopic study of 3-methyl-3-azabicyclo[3.2.1]octan-8α (and β)-olsIriepa, Isabel; Herranz, Maria José; Gálvez-Ruano, Enrique; Bellanato, Juana CSIC artículo
closedAccessaccesoRestringido.pdf.jpg1993Structural and conformational study of 3-methyl-2,4-diphenyl-3-azabicyclo[3.3.1]nonan-9α-olIriepa, Isabel; Sanz-Aparicio, J. CSIC ORCID; Fonseca, Isabel M.; Bellanato, Juana CSIC artículo
closedAccessaccesoRestringido.pdf.jpg1993Structural study of 3-methyl-2,4-diphenyl-3-azabicyclo[3.3.1]nonan-9β- olIriepa, Isabel; Gil-Alberdi, B.; Gálvez-Ruano, Enrique; Torres, R.; Gómez-Sal, Pilar; Bellanato, Juana CSIC artículo
closedAccessaccesoRestringido.pdf.jpg1-Jun-2003Structural study of 3-methyl-3-azabicyclo[3.2.1]octan-8α(and β)-ols by ab initio calculations, NMR and IR spectroscopyIriepa, Isabel; Madrid, A. I.; Morreale, Antonio; Gálvez-Ruano, Enrique; Bellanato, Juana CSIC artículo
closedAccessaccesoRestringido.pdf.jpg25-May-1999Structural, conformational and pharmacological study of some amides derived from 3-methyl-2,4-diphenyl-3-azabicyclo[3.3.1]nonan-9β-amine as potential analgesicsIriepa, Isabel; Gil-Alberdi, B.; Gálvez-Ruano, Enrique; Herranz, Maria José; Bellanato, Juana CSIC ; Carmona, Pedro CSIC; Orjales, Aurelio; Berisa, Agustín; Labeaga, Luisartículo
openAccessJOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY.pdf.jpg2019Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer’s disease therapyDgachi, Youssef; Martin, H.; Martin, Hélène; Malek, R; Jun, D.; Janockova, Jana; Sepsova, Vendula; Soukup, Ondrej; Iriepa, Isabel; Moraleda, Ignacio; Maalej, Enma; Carreiras, M. Carmo; Refouvelet, B.; Chabchoub, Fakher; Marco-Contelles, José CSIC ORCID; Ismaili, Lhassaneartículo