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RightsPreviewIssue DateTitleAuthor(s)Type
openAccessYruelaI_NatChemBiol_2016.pdf.jpg2016A proactive role of water molecules in acceptor recognition by protein O-fucosyltransferase 2Valero-González, Jessika; Leonhard-Melief, Christina; Lira-Navarrete, Erandi; Jiménez-Osés, Gonzalo CSIC ORCID; Hernández-Ruiz, Cristina; Pallarés, María Carmen; Yruela Guerrero, Inmaculada CSIC ORCID ; Vasudevan,Deepika; Lostao, Anabel; Corzana, Francisco; Takeuchi, Hideyuki; Haltiwanger, Robert S; Hurtado-Guerrero, Ramónartículo
closedAccessaccesoRestringido.pdf.jpg2013Design and synthesis of fungical transglycosidase inhibitorsGomollón-Bel, Fernando CSIC ORCID; Marca, Eduardo CSIC; Hurtado-Guerrero, Ramón; Delso, J. Ignacio; Tejero, Tomás CSIC ORCID; Merino, Pedro CSIC ORCID comunicación de congreso
openAccessCholine_Kinase.pdf.jpg31-Mar-2016Design, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase α1 (ChoKα1)Schiaffino-Ortega, Santiago; Baglioni, Eleonora; Mariotto, Elena; Bortolozzi, Roberta; Serran Aguilera, Lucia; Ríos Marco, Pablo; Carrasco-Jiménez, Maria Paz; Gallo, Miguel A.; Hurtado-Guerrero, Ramón; Marco, Carmen; Basso, Giuseppe; Viola, Giampietro; Entrena, Antonio; López-Cara, Luisa C.artículo
openAccessCytosolic_phosphoenolpyruvate_carboxykinase.pdf.jpg6-Nov-2018Dynamic acetylation of phosphoenolpyruvate carboxykinase toggles enzyme activity between gluconeogenic and anaplerotic reactionsLatorre-Muro, Pedro; Baeza, Josue; Armstrong, Eric A.; Hurtado-Guerrero, Ramón; Corzana, Francisco; Wu, Lindsay E.; Sinclair, David A.; López-Buesa, Pascual; Carrodeguas, José A.; Denu, John M.artículo
openAccessN-acetylphosphoglucosamine_mutase.pdf.jpg16-Aug-2018Evidence for substrate-assisted catalysis in N-acetylphosphoglucosamine mutaseRaimi, Olawale G.; Hurtado-Guerrero, Ramón; van Aalten, D.M.F.artículo
openAccessD0CC04847J.pdf.jpg2021Fucosyltransferase-specific inhibitionvianext generation of fucose mimeticsMartin, Kyle C.; Tricomi, Jacopo; Corzana, Francisco; García-García, Ana; Ceballos-Laita, Laura CSIC ORCID; Hicks,Thomas; Monaco, Serena; Angulo, Jesús CSIC ORCID; Hurtado-Guerrero, Ramón; Richichi, Barbara; Sakstein, Robertartículo
openAccessGenetic_structural_validation.pdf.jpg4-Sep-2013Genetic and structural validation of Aspergillus fumigatus N-acetylphosphoglucosamine mutase as an antifungal targetFang, Wenxia; Du, Ting; Raimi, Olawale G.; Hurtado-Guerrero, Ramón; Mariño, Karina; Albarbarawi, Osama; Ferguson, Michael A. J.; Jin, C.; Aalten, Daan M. F. vanartículo
openAccessAspergillus_fumigatus.pdf.jpg10-Jun-2013Genetic and structural validation of Aspergillus fumigatusUDP-N-acetylglucosamine pyrophosphorylase as an antifungal targetFang, Wenxia; Du, Ting; Raimi, Olawale G.; Hurtado-Guerrero, Ramón; Urbaniak, Michael D.; Ibrahim, Adel F. M.; Ferguson, Michael A. J.; Jin, Cheng Jun; van Aalten, D.M.F.artículo
closedAccessaccesoRestringido.pdf.jpg2016Glycomimetics targeting glycosyltransferases: Synthetic, computational and structural studies of less-polar conjugatesGhirardello, Mattia CSIC ORCID; Rivas, Matilde de las; Lacetera, Alessandra; Delso, J. Ignacio; Lira-Navarrete, Erandi; Tejero, Tomás CSIC ORCID; Martín-Santamaría, Sonsoles CSIC ORCID ; Hurtado-Guerrero, Ramón; Merino, Pedro CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2018Inhibitors against fungal cell wall remodeling enzymesDelso, J. Ignacio; Valero-González, Jessika; Gomollón-Bel, Fernando CSIC ORCID; Castro-López, Jorge; Fang, Wenxia; Navratilova, Iva; Aalten, Daan M. F. van; Tejero, Tomás CSIC ORCID; Merino, Pedro CSIC ORCID ; Hurtado-Guerrero, Ramónartículo
openAccessmolecut3.pdf.jpg2020Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3Rivas, Matilde de las; Paul Daniel, Earnest James; Narimatsu, Yoshiki; Compañón, Ismael; Kato, Kentaro; Hermosilla, Pablo; Thureau, Aurélien; Ceballos-Laita, Laura CSIC ORCID; Coelho, Helena; Bernardó, Pau; Marcelo, Filipa CSIC ORCID; Hansen, Lars; Maeda, Ryota; Lostao, Anabel; Corzana, Francisco; Clausen, Henrik; Gerken, Thomas A.; Hurtado-Guerrero, Ramónartículo
closedAccessaccesoRestringido.pdf.jpg2016New glycomimetics targeting human GalNAc-T2, synthesis, computational and structural studiesGhirardello, Mattia CSIC ORCID; Delso, J. Ignacio; Tejero, Tomás CSIC ORCID; Martín-Santamaría, Sonsoles CSIC ORCID ; Hurtado-Guerrero, Ramón; Merino, Pedro CSIC ORCID póster de congreso
openAccessd1sc04065k.pdf.jpg2021NleB/SseK-catalyzed arginine-glycosylation and enteropathogen virulence are finely tuned by a single variable position contiguous to the catalytic machineryGarcía-García, Ana; Hicks,Thomas; El Qaidi, Samir; Zhu, Congrui; Hardwidge, Philip R.; Angulo, Jesús CSIC ORCID; Hurtado-Guerrero, Ramónartículo
closedAccessaccesoRestringido.pdf.jpg2015Obtención de nuevos inhibidores enzimáticos para transglicosidasas de Aspergillus fumigatus mediante click chemistryGomollón-Bel, Fernando CSIC ORCID; Delso, J. Ignacio; Hurtado-Guerrero, Ramón; Tejero, Tomás CSIC ORCID; Merino, Pedro CSIC ORCID comunicación de congreso
openAccessCholine_kinase.pdf.jpg1-Jun-2015Pharmacophore-Based Virtual Screening to Discover New Active Compounds for Human Choline Kinase α1Serran Aguilera, Lucia; Nuti, Roberto; López-Cara, Luisa C.; Gallo Meza, Miguel Angel; Macchiarulo, Antonio; Entrena, Antonio; Hurtado-Guerrero, Ramónartículo
openAccessaccesoRestringido.pdf.jpg28-Jan-2019Polypeptide GalNAc-Ts: from redundancy to specificityde las Rivas, Matilde; Lira-Navarrete, Erandi; Gerken, T.A.; Hurtado-Guerrero, Ramónartículo
openAccessproteisoluti.pdf.jpg2021Protein O-fucosyltransferase 1 undergoes interdomain flexibility in solutionLira-Navarrete, Erandi; Pallarés, María C.; Castello, Fabio; Ruedas-Rama, Maria J.; Orte, Angel; Lostao, Anabel; Hurtado-Guerrero, Ramónartículo
openAccesstransglycosylase Gas2.pdf.jpg2016Rational design of glycomimetic compounds targeting the Saccharomyces cerevisiae transglycosylase Gas2Delso, J. Ignacio; Valero-González, Jessika; Marca, Eduardo CSIC; Tejero, Tomás CSIC ORCID; Hurtado-Guerrero, Ramón; Merino, Pedro CSIC ORCID artículo
closedAccessaccesoRestringido.pdf.jpg2012Recent progress on fucosyltransferase inhibitorsMerino, Pedro CSIC ORCID ; Tejero, Tomás CSIC ORCID; Delso, J. Ignacio; Hurtado-Guerrero, Ramón; Gómez-SanJuan, Asier; Sádaba, David CSIC ORCIDartículo
openAccessselfactivity.pdf.jpg2021Self-acetylation at the active site of phosphoenolpyruvate carboxykinase (PCK1) controls enzyme activityLatorre-Muro, Pedro; Baeza, Josue; Hurtado-Guerrero, Ramón; Hicks,Thomas; Delso, J. Ignacio; Hernández-Ruiz, Cristina; Velázquez-Campoy, Adrián; Lawton, Alexis J.; Angulo, Jesús CSIC ORCID; Denu, John M.; Carrodeguas, José A.artículo