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Browsing by Author Hamel, Ernest

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Showing results 1 to 7 of 7
RightsPreviewIssue DateTitleAuthor(s)Type
closedAccess2007Arylthioindole inhibitors of tubulin polymerization. 3. Biological evaluation, structure-activity relationships and molecular modeling studiesLa Regina, Giuseppe; Edler, Michael C.; Brancale, Andrea; Kandil, Sahar; Coluccia, Antonio; Piscitelli, Francesco; Hamel, Ernest; De Martino, Gabriella; Matesanz, Ruth CSIC ; Díaz, José Fernando CSIC ORCID ; Scovassi, Anna Ivana; Prosperi, Ennio; Lavecchia, Antonio; Novellino, Ettore; Artico, Marino; Silvestri, Romanoartículo
closedAccessaccesoRestringido.pdf.jpg30-Aug-2005Cyclostreptin (FR182877), an Antitumour Tubulin-Polymerizing Agent Deficient in Enhancing Tubulin Assembly Despite Its High Affinity for the Taxoid SiteEdler, Michael C.; Martínez Buey, Rubén CSIC ORCID CVN; Gussio, Rick; Marcus, Adam I.; Vanderwal, Christopher D.; Sorensen, Erik J.; Díaz, José Fernando CSIC ORCID ; Giannakakou, Paraskevi; Hamel, Ernestartículo
openAccesscyclostreptin_Buey.pdf.jpgJan-2007Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sitesMartínez Buey, Rubén CSIC ORCID CVN; Calvo, Enrique; Barasoain, Isabel CSIC ; Pineda, Oriol; Edler, Michael C.; Matesanz, Ruth CSIC ; Cerezo, Gemma; Vanderwal, Christopher D.; Day, Billy W.; Sorensen, Erik J.; López, Juan Antonio; Andreu, José Manuel CSIC ORCID ; Hamel, Ernest; Díaz, José Fernando CSIC ORCID artículo
closedAccessrestringido.pdf.jpgJan-2012Cyclostreptin Derivatives Specifically Target Cellular Tubulin and Further Map the Paclitaxel SiteCalvo, Enrique; Barasoain, Isabel CSIC ; Matesanz, Ruth CSIC ; Pera, Benet CSIC; Camafeita, Emilio; Pineda, Oriol; Hamel, Ernest; Vanderwal, Christopher D.; Andreu, José Manuel CSIC ORCID ; López, Juan Antonio; Díaz, José Fernando CSIC ORCID artículo
closedAccessrestringido.pdf.jpgMar-2008The interaction of a cyclostreptin analogue with the microtubule: The covalent reaction rapidly follows bindingBai, Ruoli; Vanderwal, Christopher D.; Díaz, José Fernando CSIC ORCID ; Hamel, Ernestartículo
closedAccessaccesoRestringido.pdf.jpg1-Jun-2011Zampanolida, un novedoso agente estabilizador de microtubulos quew se une covalentemente al sitio de paclitaxelField, Jessica J.; Pera, Benet CSIC; Canales, Ángeles CSIC ORCID; Zuwerra, D.; Trigili, Chiara CSIC; Kanakkanthara, Arun; Wakefield, St. John; Singh, A. Jonathan; Jiménez-Barbero, Jesús CSIC ORCID; Northcote, Peter; Miller, J.; López, Juan Antonio; Hamel, Ernest; Barasoain, Isabel CSIC ; Altmann, Karl-Heinz; Díaz, José Fernando CSIC ORCID póster de congreso
openAccessField et al 2012_Chemistry and Biology.pdf.jpg22-Jun-2012Zampanolide, a potent new microtubule stabilizing agent, covalently reacts with the taxane luminal site in both tubulin alpha-beta-heterodimers and microtubulesField, Jessica J.; Pera, Benet CSIC; Calvo, Enrique; Canales, Ángeles CSIC ORCID; Zurwerra, Didier; Trigili, Chiara CSIC; Rodríguez-Salarichs, Javier; Matesanz, Ruth CSIC ; Kanakkanthara, Arun; Wakefield, St. John; Singh, A. Jonathan; Jiménez-Barbero, Jesús CSIC ORCID; Northcote, Peter; Miller, John H.; López, Juan Antonio; Hamel, Ernest; Barasoain, Isabel CSIC ; Altmann, Karl-Heinz; Díaz, José Fernando CSIC ORCID artículo