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Browsing by Author García Fernández, José Manuel

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openAccessWO2023073005A1.pdf.jpg4-May-20235-Aminohexahydro-6,7,8-trihydroxy-3H-oxazolo[3,4-a]pyridin-3-one derivatives derivatives as TLR4 modulators for the treatment of immune diseasesGarcía Fernández, José Manuel CSIC ORCID; Ortiz-Mellet, Carmen; González-Cuesta, Manuel; Sánchez-Fernández, Elena M. CSIC ORCID; Chang, Ya-Jen; Lai, Alan Chuan-Yingsolicitud de patente
openAccessEP4174075A1.pdf.jpg3-May-20235-Aminohexahydro-6,7,8-trihydroxy-3H-oxazolo[3,4-a]pyridin-3-one derivatives derivatives as TLR4 modulators for the treatment of immune diseasesGarcía Fernández, José Manuel CSIC ORCID; Ortiz-Mellet, Carmen; González-Cuesta, Manuel; Sánchez-Fernández, Elena M. CSIC ORCID; Chang, Ya-Jen; Lai, Alan Chuan-Yingsolicitud de patente
closedAccess13-May-20096-Amino-6-deoxy-5,6-di-N-(N′-octyliminomethylidene)nojirimycin: Synthesis, Biological Evaluation, and Crystal Structure in Complex with Acid β-GlucosidaseBrumshtein, Boris; Aguilar Moncayo, Matilde; García Moreno, María Isabel; Ortiz-Mellet, Carmen; García Fernández, José Manuel CSIC ORCID; Silman, Israel; Shaaltiel, Yoseph; Aviezer, David; Sussman, Joel L.; Futerman, Anthony H.artículo
closedAccess9-Nov-2010A Fluorescent sp2-Iminosugar With Pharmacological Chaperone Activity for Gaucher Disease: Synthesis and Intracellular Distribution StudiesLuan, Zhuo; Higaki, Katsumi; Aguilar Moncayo, Matilde; Li, Linjing; Ninomiya, Haruaki; Nanba, Eiji; Ohno, Kousaku; García Moreno, María Isabel; Ortiz-Mellet, Carmen; García Fernández, José Manuel CSIC ORCID; Suzuki, Yoshiyukiartículo
openAccesss108842461750033x.pdf.jpg2017A novel potential nanophototherapeutic based on the assembly of an amphiphilic cationic ß-cyclodextrin and an anionic porphyrinMazzaglia, Antonio; Micali, Norberto; Villari, Valentina; Zagami, Roberto; Pennisi, R.M.; Ortiz-Mellet, Carmen; García Fernández, José Manuel CSIC ORCID; Sciortino, M.T.; Scolaro, L.M.artículo
closedAccessaccesoRestringido.pdf.jpgFeb-2016Aerosolized non-viral nucleic acid delivery in the vaginal tract of pigsRemaut, Katrien; Clercq, Evelien de; Andries, Oliwia; Rombouts, Koen; Van Gils, Matthias; Cicchelero, Laetitia; Vandenbussche, Ian; Van Praet, Sarah; Benito, Juan M. CSIC ORCID CVN ; García Fernández, José Manuel CSIC ORCID; Sanders, Niek; Vanrompay, Daisyartículo
openAccessfimmu-12-632132.pdf.jpg2021Anti-Inflammatory (M2) Response Is Induced by a sp2-Iminosugar Glycolipid Sulfoxide in Diabetic RetinopathyCano-Cano, Fátima; Alcalde-Estévez, Elena; Gómez-Jaramillo, Laura; Iturregi, Marta; Sánchez-Fernández, Elena M. CSIC ORCID; García Fernández, José Manuel CSIC ORCID; Ortiz Mellet, Carmen; Campos-Caro, Antonio CSIC ORCID; López-Tinoco, Cristina; Aguilar-Diosdado, Manuel; Valverde, Ángela M. CSIC ORCID ; Arroba, Ana I. CSIC ORCIDartículo
openAccessc5ra02627j.pdf.jpg2015Antileishmanial activity of sp2-iminosugar derivativesSánchez-Fernández, Elena M. CSIC ORCID; Gómez-Pérez, Veronica; García-Hernández, Raquel CSIC ORCID; García Fernández, José Manuel CSIC ORCID; Plata, Gabriela B.; Padrón, José M.; Ortiz-Mellet, Carmen; Catanys, Santiago; Gamarro, Franciscoartículo
openAccessBicyclic (galacto)nojirimycin analogues as glycosidase inhibitors.pdf.jpg2011Bicyclic (galacto)nojirimycin analogues as glycosidase inhibitors: Effect of structural modifications in their pharmacological chaperone potential towards β-glucocerebrosidaseAguilar Moncayo, Matilde; García-Moreno, M. Isabel; Trapero, Ana CSIC ORCID; Egido-Gabás, Meritxell CSIC; Llebaria, Amadeu CSIC ORCID; García Fernández, José Manuel CSIC ORCID; Ortiz-Mellet, Carmenartículo
closedAccessaccesoRestringido.pdf.jpg2013Bicyclic Derivatives of L-Idonojirimycin as Pharmacological Chaperones for Neuronopathic Forms of Gaucher DiseaseAlfonso Palacin, Pilar; Andreu, Vanesa; Pino-Ángeles, Almudena; Moya García, Aurelio; García-Moreno, M. Isabel; Rodríguez, Rey, José C.; Sánchez-Jiménez, Francisca; Pocovi Mieras, Miguel; García Fernández, José Manuel CSIC ORCID; Giraldo, Pilarartículo
openAccessBBA-Gen. Subjects 2017 accepted.pdf.jpg2017Biophysics and protein corona analysis of Janus cyclodextrin-DNA nanocomplexes. Efficient cellular transfection on cancer cellsMartínez-Negro, María; Caracciolo, G.; Palchetti, S.; Pozzi, D.; Capriotti, A.L.; Cavaliere, C.; Laganà, A.; Ortiz-Mellet, Carmen; Benito, Juan M. CSIC ORCID CVN ; García Fernández, José Manuel CSIC ORCID; Aicart, Emilioartículo
openAccessUS2010086648A1-1.pdf.jpg8-Apr-2010Caramels with high content in prebiotic oligosaccharides, procedure of preparation and useRubio Castillo, Enrique Miguel CSIC; Gómez García, Marta; Ortiz-Mellet, Carmen; García Fernández, José Manuel CSIC ORCID; Zarzuelo Zurita, Antonio; Gálvez Peralta, Juan Julio; Duval, Raphaëlsolicitud de patente
openAccess2020Carbohydrate supramolecular chemistry: beyond the multivalent effectGonzález-Cuesta, Manuel; Ortiz Mellet, Carmen; García Fernández, José Manuel CSIC ORCIDartículo
closedAccessaccesoRestringido.pdf.jpg2-Aug-2017Carbon dioxide as a traceless caramelization promotor: preparation of prebiotic difructose dianhydrides (DFAs)-enriched caramels from d -FructoseAudemar, Maite; Atencio-Genes, Loyda; Ortiz-Mellet, Carmen; Jérôme, François; García Fernández, José Manuel CSIC ORCID; Oliveira Vigier, K. deartículo
closedAccessaccesoRestringido.pdf.jpg22-Aug-2018Catalyst-free synthesis of alkylpolyglycosides induced by high-frequency ultrasoundNana Amaniampong, Prince; Clément, Jean-Louis; Gigmes, Didier; Ortiz-Mellet, Carmen; García Fernández, José Manuel CSIC ORCID; Blériot, Yves; Chatel, Gregory; Oliveira Vigier, Karine de; Jérime, Françoisartículo
openAccessCell Uptake Mechanisms of Glycosylated Cationic pDNA-CDs NPs (after revison; accepted).pdf.jpg2015Cell uptake mechanisms of glycosylated cationic pDNA-cyclodextrin nanoparticlesGuilloteau, Nicolas; Bienvenu, Céline; Charrat, Coralie; Jiménez Blanco, José L.; Díaz Moscoso, Alejandro CSIC ORCID ; Ortiz-Mellet, Carmen; García Fernández, José Manuel CSIC ORCID; Vierling, Pierre; Di Giorgio, Christopheartículo
openAccess2021Challenge 7: Advanced TherapiesBachiller, Daniel CSIC ORCID; Serrano, María C. CSIC ORCID ; García Fernández, José Manuel CSIC ORCID; Boscá, Lisardo CSIC ORCID CVN ; Casado, Marta CSIC ORCID ; Bernad, Antonio CSIC ORCID; Álvarez-Dolado, Manuel CSIC ORCID CVN; Villa, Rosa CSIC ORCID ; Nácher, Enrique CSIC ORCID; Sánchez, Ana; Cano González, David A. CSIC ORCID; Veiga, Esteban CSIC ORCID ; Rodríguez, Fernando; Albiol, Francisco Javier; Llosá, Gabriela CSIC ORCID; Ratera, Immaculada; Frade López, José María CSIC ORCID ; Zapata, Manuel CSIC; Tapia, Natalia CSIC ORCID; Merino, Ramón CSIC ORCIDcapítulo de libro
closedAccess14-Oct-2009Chaperone Activity of Bicyclic Nojirimycin Analogues for Gaucher Mutations in Comparison with N-(n-nonyl)DeoxynojirimycinLuan, Zhuo; Higaki, Katsumi; Aguilar Moncayo, Matilde; Ninomiya, Haruaki; Ohno, Kousaku; García Moreno, María Isabel; Ortiz-Mellet, Carmen; García Fernández, José Manuel CSIC ORCID; Suzuki, Yoshiyukiartículo
openAccessChemical_2008.pdf.jpg12-Aug-2008Chemical and Enzymatic Approaches to Carbohydrate-Derived Spiroketals: Di-D-Fructose Dianhydrides (DFAs)García Moreno, María Isabel; Benito, Juan M. CSIC ORCID CVN ; Ortiz-Mellet, Carmen; García Fernández, José Manuel CSIC ORCIDartículo
openAccess2346506_A1.pdf.jpg15-Oct-2010Ciclooligosacáridos anfifílicos policatiónicos y su uso como transportadores molecularesOrtiz-Mellet, Carmen; Méndez-Ardoy, Alejandro CSIC ORCID; Gómez García, Marta; Sevillano Trapero, Natalia; Girón González, María Dolores; Salto González, Rafael; Santoyo-González, F.; García Fernández, José Manuel CSIC ORCIDsolicitud de patente